Articles tagged with Depression
Indiana University-Purdue University Indianapolis researchers led by Jesse Stewart are conducting a randomized controlled trial to investigate the effect of depression treatment on heart attack risk. The study aims to confirm that treating depression is cardioprotective, lowering cardiovascular disease risk.
A large-scale trial of deep brain stimulation for treatment-resistant depression found no significant reduction in symptoms. The study's results challenge the use of this therapy for depression, but experts suggest alternative approaches may be beneficial.
A recent study has discovered a blood marker that can help identify women at risk for postpartum depression, a debilitating disorder affecting nearly 20% of new mothers. The oxytocin receptor marker is associated with increased risk and may enable early identification and intervention.
A new study suggests that ultra-brief pulse stimulation is almost as effective as standard ECT in treating severe depression, but with significantly fewer cognitive side effects. The treatment has the potential to benefit up to 10,000 Australians who have not responded to first-line treatments.
Researchers at UT Southwestern Medical Center found that increasing cyclic adenosine monophosphate (cAMP) in brain cells can improve stress response and potentially treat depression. The study's findings suggest a new therapeutic target for depression treatment, offering hope for patients who have not responded to existing therapies.
A study from Duke University found that children with even mild psychiatric issues are more likely to face challenges in adulthood, including criminal charges, addictions, and education failures. The research suggests that early interventions can prevent these problems, but many children do not receive the necessary treatment.
A study by Northwestern University found that smartphone sensor data can detect depression with 87% accuracy, analyzing time spent on phones and daily locations. The research uses GPS tracking and algorithms to identify patterns associated with depression, paving the way for passive detection and potential interventions.
A new study aims to increase the accessibility of mental health research in community clinics by developing practical measures for implementing evidence-based practices. The project will explore two methods for integrating measurement-based care into routine clinical work.
A study found that over 82% of people with depression in the general population are not eligible for clinical trials of antidepressant drugs. The trials use strict inclusion and exclusion criteria, which can exclude patients based on age, medical conditions, or severity of depression.
Scientists have identified promising compounds that could treat depression in less than 24 hours while minimizing side effects. The compounds, called GABA-NAMs, target the brain's excitatory and inhibitory communication, restoring balance and relieving symptoms.
Children of depressed mothers who show increased pupil dilation to sad faces are at higher risk of developing depressive symptoms and diagnoses over two years. The study suggests pupillometry could be used as a low-cost tool for pediatricians to identify children at highest risk.
A study published in Gut found that anxiety and depression prior to a water contamination incident increased the severity of gastrointestinal infections and the risk of developing irritable bowel syndrome. Psychological factors can play a key role in preventing long-term complications.
A study of 200 adult men found that those with borderline testosterone levels had a 56% rate of depression and depressive symptoms, highlighting the importance of screening for mental health in this population. The researchers also identified high rates of obesity and low physical activity as contributing factors.
A global study has found that people with recurrent depression have a significantly smaller hippocampus than healthy individuals. The study, involving nearly 9,000 participants, highlights the need for effective treatment at first occurrence, particularly among teenagers and young adults.
Researchers argue that current diagnosis methods for depression are flawed and that understanding 'normal' emotional responses can help inform clinical practice. Increased interaction between fundamental emotion research and practitioner training is necessary to ensure accurate diagnosis and treatment of emotional disorders.
New research suggests that depressed people often choose to increase rather than decrease their sadness in daily life. Studies found that depressed participants preferred sad music and re-watched sad images more frequently than non-depressed individuals. The findings highlight the importance of motivation in regulating emotions.
A randomized trial of daily oral HIV pre-exposure prophylaxis (PrEP) in men and transgender women who have sex with men found no link between Truvada use and depression. Half of participants reported clinically significant depression, highlighting the need for further research on PrEP's impact during vulnerable times.
Researchers have found that artificially reactivating positive memories can suppress the effects of stress-induced depression in mice. The study reveals how brain circuits interact with negative experiences and provides a potential target for therapeutic approaches.
A new study published in Clinical Psychological Science found that women with a past history of depression who pay more attention to angry faces are at greatest risk for developing depression again over the next two years. Researchers used eye-tracking to analyze the attention of 160 women, including those with and without depression, ...
Researchers found shorter telomeres in preschoolers with oppositional defiant behavior, a hallmark of cellular aging. Maternal clinical depression also correlates with telomere length, with children of depressed mothers having shorter telomeres at ages 4 and 5.
Researchers discovered unique white matter injury patterns in patients with concussion-related depression and anxiety, suggesting similar mechanisms to non-trauma dependent depression. Anxiety patients showed diminished fractional anisotropy in the brain's fear modulation region, indicating different treatment targets may be required.
A study of over 69,000 individuals in Sweden found no association between varenicline and increased risks of suicidal behaviours, criminal offending, transport accidents, or psychoses. However, a small increased risk was found in individuals with pre-existing psychiatric disorders during periods of medication.
A new study by Naguib Mechawar's team found that networks of astrocytes are altered specifically in areas of the brain associated with mood regulation. The research also discovered unique properties of astrocytes in subcortical brain regions, which may contribute to depression and suicide.
A pilot study reveals significant early results for the program, with a 28% decrease in depression scores and 12% decrease in anxiety scores among students. The program has also led to a decrease in suicidal thinking and improved mental health outcomes.
A long-term study in Pakistan found that prenatal treatment for depression had no effect on children's emotional and behavioral development. In contrast, maternal depression was linked to worse child outcomes, emphasizing the need for integrated maternal and child health programs.
A new study found that people with a certain genetic variant, short alleles of the gene 5-HTTLPR, displayed greater genuine smiling and laughing while watching cartoons or subtly amusing film clips. The research suggests that this genetic variant may be associated with positive emotional expressions.
Researchers found a modest reduction in depressive symptoms among some surviving spouses of hospice users compared with non-hospice users. Hospice care was associated with improved depression scores for a subgroup of surviving spouses, particularly those who were primary caregivers.
Research presented at Heart Failure 2015 reveals moderate to severe depression is associated with a 5-fold increased risk of all-cause mortality in patients with heart failure. Patients with moderate to severe depression had an 80% lower mortality risk compared to those without or mild depression.
Researchers found individuals with elevated depressive symptoms performed poorly hearing all categories of speech, not just sad speech, in cocktail party-like environments. The study's findings suggest a broader issue with emotion-general deficit in speech perception for those with depression.
A systematic review of six randomised controlled trials found that antidepressants were of benefit for postnatal depression, with 54% of participants reporting 'much improved' symptoms after treatment. Remission rates were also improved, with 49% of participants showing remission compared to 26% in the placebo group.
A new study from the University of Edinburgh found that individuals with high psychological distress were more likely to die from liver disease. The research tracked over 165,000 participants for ten years and controlled for various factors such as alcohol consumption and socioeconomic status.
The UTSW Center for Depression Research and Clinical Care aims to replace the current trial-and-error approach with personalized medicine. Dr. Madhukar Trivedi will lead the center, which will use clinical data and biosignatures to drive precision medicine.
Dr. Madhukar Trivedi, a renowned expert in depression and mood disorders, received the American Psychiatric Association Award for his significant contributions to the field. His research has led to notable advances in treatment strategies and patient outcomes.
The Lancet Diabetes & Endocrinology publishes a series on depression and diabetes, revealing a bi-directional association between the two conditions. The studies also suggest that depression-distress mediates the association between depression and glycaemic control.
A University of Maryland study found that men and women in the US had lower odds of depression diagnoses and better mental health during the Great Recession compared to pre-recession. Women were more likely to be diagnosed with anxiety disorders post-recession, while men experienced less psychological distress.
Women with depression and bipolar disorder performed poorly on a test of cognitive control, which requires sustained concentration. Brain scans showed different levels of activity in the right posterior parietal cortex compared to healthy women.
A new study supports the screening and treatment of depression in brain tumor patients, who are at high risk of depressive symptoms that can impact care outcomes. The authors recommend using reliable screening tools and refer patients with positive results for detailed psychiatric assessment.
Researchers discovered a metabolic signature associated with major depression, including changes in mitochondrial DNA and telomere length. The findings suggest that depression may be linked to the body's response to environmental stressors.
The study found a significant increase in major depression among US adults during the Great Recession, with prevalence rising from 2.33% to 3.79%. Less severe depression also saw a decline in prevalence after 2009-2010. Vulnerable populations such as those living in poverty or with less than a high school education were most affected.
Researchers found that mindfulness-based cognitive therapy (MBCT) is not more effective than maintenance antidepressant medication in preventing depression relapse. However, MBCT may offer similar protection against depressive relapse for people with a history of multiple episodes, with no significant cost difference.
A leading psychiatrist argues that depression is not caused by low serotonin levels and that effective treatments do not raise these levels. The serotonin reuptake inhibiting drug class, popularized in the late 1980s, was marketed despite lacking evidence of its effectiveness.
A large study found that mindfulness-based cognitive therapy (MBCT) is comparable in preventing depression relapse to maintenance antidepressant medication. The therapy may offer a cost-effective and low-cost option for individuals with recurrent depression.
Researchers at UNC School of Medicine found that a low dose of electric current enhances alpha wave oscillations, boosting creativity by 7.4% in healthy adults. The study's results now pave the way for testing this protocol to alleviate symptoms in people with depression.
A study of over 2.4 million Danish citizens found that depression, type 2 diabetes, or both are associated with a higher risk of dementia. Individuals diagnosed with depression or type 2 diabetes alone have an increased risk, while those with both conditions experience the greatest increase in risk.
A wristband that measures motion throughout a 24-hour cycle may help identify patients with major depressive disorder who will respond best to commonly prescribed drugs like Prozac. The study found that night owls are more likely to be depressed and respond to SSRIs.
A new suite of interactive mini-apps called Intellicare provides personalized therapy for depression and anxiety. The app uses a recommender system to suggest tailored apps based on user feedback and preferences.
Research from San Francisco State University reveals that fertility treatment patients are more likely to experience major depressive disorder (MDD) than the general population. A key factor in predicting a patient's risk is whether they have a previous diagnosis of MDD, which is often overlooked by healthcare providers.
A new study suggests that symptoms of depression and insomnia are the strongest predictors of having frequent nightmares. Researchers found a strong connection between well-being and nightmares, particularly in individuals with severe depressive symptoms.
A study of 14,348 Swiss individuals found that those with depressive symptoms have a higher risk of developing physical diseases, especially arthrosis and arthritis. The researchers suggest that lack of interest in physical activity or inflammatory processes may be key factors in this association.
Training pediatric primary care providers improved their confidence and knowledge of adolescent depression, increasing screening frequency. The study found that providers who received training were more likely to identify early signs of depression and discuss treatment options with patients.
A study published in The Journal of Nervous and Mental Disease found that 'religiously integrated' cognitive-behavioral therapy is at least as effective as conventional CBT for treating major depression in chronically ill patients. Highly religious patients showed greater improvement with this approach.
Researchers found that ECT alters the hippocampus and amygdala, structures linked to mood and learning, in patients with major depression. These changes correlated with improved mood and treatment response.
A new peer-to-peer networking tool has been developed to build online support communities and practice therapeutic techniques for depression. The tool, called Panoply, yielded better outcomes in training subjects to use cognitive reappraisal and improving mood in those with severe symptoms.
A new mobile phone app, LifeRhythm, detects depression symptoms by analyzing user behavior such as activity levels and social interactions. The technology has the potential to revolutionize depression diagnosis, providing an objective and automated screening method.
A new study found that anhedonia, the inability to gain pleasure, is associated with more severe depression and worse outcomes in adolescents. Anhedonia severity showed a significant correlation with overall outcomes, including illness severity and episode duration.
A study of 1,052 mothers found that domestic violence was associated with a higher risk of depression and schizophrenia-like psychotic symptoms in women. The research also highlighted the importance of considering childhood abuse as a factor in predicting mental health outcomes.
Military veterans with avoidant coping strategies exhibit higher symptoms of depression and generalized anxiety, but emotional support reduces negative impacts. Problem-focused coping with high emotional support is linked to lower depression and anxiety symptoms.
A study led by the University of Pennsylvania found that roseroot extract may be an effective treatment for mild to moderate major depressive disorder, with fewer side effects than conventional antidepressants. The herbal remedy showed a more favorable risk-to-benefit ratio, suggesting its potential as an alternative therapy option.
Researchers found that hypobaric hypoxia caused increased depression-like behavior in female rats at high altitudes. The study suggests that altitude is an independent risk factor for depression and suicide, and physiological changes triggered by low oxygen may contribute to the issue.
A new project at the University of Illinois is using tablet computers to provide perinatal depression screenings to low-income mothers. The mHealth technology allows women to complete the screening in their preferred language and provides a paperless alternative to traditional screenings.