Articles tagged with Drug Abuse
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A review panel led by Regenstrief Institute Research Scientist Kurt Kroenke found that clinicians, policymakers, and payers are misapplying CDC opioid guidelines, negatively affecting patients. The panel identified challenges with implementing the guidelines, including overly restrictive prescribing policies and burdens on clinicians.
A new program aims to prevent substance abuse among children and parents, offering tailored classes and social norms campaigns to reduce alcohol and e-cigarette use. The initiative, funded at $1.4 million, also provides referrals to support groups and smoking cessation classes.
Researchers identified risks associated with popular alternative treatments like kratom, Imodium, and Xanax, which can cause substantial side effects and high abuse rates. The study also found that 'stacks' or kits combining substances are being used to combat withdrawal symptoms.
The University of Houston College of Pharmacy has opened a new center to educate providers and patients on safe controlled substance prescription use, aiming to optimize pharmacotherapy for pain management. The PREMIER Center will also support the safe disposal of unused medications through a $3.34 million grant.
A study published in PLOS Biology found that oxytocin administration can block excess drinking in alcohol-dependent rats, suggesting a potential novel pharmaceutical intervention for treating alcohol-use disorder. Oxytocin also blocked altered GABA signaling in the brain region affected by alcohol dependence.
A new research project aims to investigate how opioid use is treated in adolescence, a significant public health problem. The study will analyze insurance claims data to identify patterns of opioid use leading up to addiction and long-term treatment outcomes.
A study found that at least six states with high opioid abuse rates have restrictive scopes of practice for nurse practitioners, limiting their ability to prescribe medications like buprenorphine. In less restrictive states, NPs were more likely to receive waivers and access these life-saving medications.
A new study published in Addiction found that medication treatment for opioid use disorder significantly reduces the risk of arrest and incarceration. The research, led by UMass Amherst public health scientist Elizabeth Evans, used data from a large randomized clinical trial to compare the effects of two medications on social outcomes.
A color test developed at University of Technology Sydney can accurately detect all cathinones, a new illicit synthetic drug entering the market every four days. The test is now commercialized and being marketed to police and customs agencies in Europe, offering a solution for detecting new psychoactive substances.
A new computer model, NarcoLogic, reveals that cocaine interdiction strategies actually fuel the spread of trafficking networks. The study suggests that decades of war on drugs have had little effect on reducing cocaine supply or prices, and that increased interdiction will only push traffickers into new areas.
The article discusses the rising trend of heroin abuse in the US, which has led to an increase in surgical complications such as skin and soft tissue infections, septic thrombophlebitis, and mycotic pseudoaneurysms. Rapid recognition and management of these complications are crucial to prevent life-threatening outcomes.
Researchers found that men who stopped using performance-enhancing hormones experienced complete recovery of sperm production and hormone levels within nine to 18 months. However, testicular size remained smaller than normal in some cases. The study provides valuable insights for endocrinologists caring for men affected by androgen abuse.
Researchers have developed a novel method for detecting amphetamine and ketamine in latent fingermarks using nanocarrier-based biological fluorescent probes. The method allows for simultaneous detection of multiple drugs in a single fingerprint, providing a potential solution to combat drug abuse.
A biomedical engineer is developing a therapeutic option that would prevent the opiates from crossing the blood-brain barrier, preventing the high abusers seek. The treatment involves generating an anti-opioid antibody that will arrest the drug in circulation and prevent it from getting to the brain.
Nonmedical prescription drug use leads to 360,000 ED visits in US, mostly benzodiazepines and opioids; young adults under 35 most affected. The study proposes expanding naloxone distribution and implementing screening for polysubstance use.
Hospital admissions for drug-related infective endocarditis increased by 436% at a medical center in the US, with heroin implicated in most cases. Patients who inject drugs are at risk of developing this condition due to contaminated needles introducing bacteria into their bloodstream.
A new study reveals that the menstrual cycle phase may contribute to differences between men and women in cocaine seeking and vulnerability to relapse after quitting. Female rats exhibited stronger cravings for cocaine during estrus, a phase associated with ovulation, compared to non-estrus.
University of Guelph researchers found that environmental cues activate brain areas where memories are processed, making it difficult to counter addiction. This study could have implications for treating drug addiction in humans.
Researchers found that most individuals misusing prescription opioids also use cigarettes, alcohol, marijuana or hard drugs. Those who misuse multiple substances have a greater risk of behavioral problems, mental health issues and treatment needs.
A new study estimates that 3.9 million US adults misused prescription opioids annually, with risk factors including co-occurring substance use disorders and psychological distress. Prescribers should be vigilant about potential misuse among patients prescribed potent opioid medications for long-term use.
Overdoses from opioids in loperamide have increased nationwide, with cardiac failure being a major concern due to the high toxicity of the drug when misused. Misusing non-prescription loperamide can lead to serious consequences, including irregular heartbeat and cardiac arrest.
A study by RAND Corporation finds that OxyContin reformulation in 2010 led to a large rise in hepatitis C infections as drug abusers switched to injectable heroin. States with higher rates of OxyContin misuse prior to the reformulation saw a three-fold increase in hepatitis C infections.
A new study found that most medical marijuana users in the US are treating chronic pain, with 85.5% of patients reporting an evidence-based condition. The study analyzed data from states with legalized medical use of marijuana and found a dramatic increase in patient numbers over time.
A new 'Cascade of Care' framework aims to address gaps in addiction care and monitor treatment outcomes for individuals with opioid use disorder. The model identifies key stages through which people must progress to increase the chance of reaching remission, and emphasizes prevention services targeting populations by risk level.
A new study found that adolescents and young adults in liberal states reported higher past-year cannabis use rates than those in conservative states. However, the rates of cannabis use disorder were significantly lower in liberal states compared to conservative states for ages 12-17 and marginally lower for ages 26 and older.
A new study from Johns Hopkins Bloomberg School of Public Health found that only 36.1% of US outpatient treatment centers offer medication treatment for opioid use disorder, with significant variation among states. Treatment facilities in Medicaid expansion states were more likely to offer medication treatment.
A new clinical review recommends medication-assisted treatment for patients experiencing opioid withdrawal, which can help ease them into longer-term treatment and recovery. Buprenorphine is the preferred medication for most patients, particularly in emergency department settings.
The Second Chance app uses sonar to monitor breathing rate and detect opioid overdose symptoms. It has been shown to accurately identify overdoses 90% of the time and can track movement and breathing from a distance.
DeepSqueak uses deep artificial neural networks to analyze ultrasonic vocalizations, providing a new tool for studying social behavior in rodents. The researchers found that male mice have distinct songs for different stages of courtship, and that they are more complex when sensing a female mouse nearby.
The study analyzed data from over 69,000 ED visits for patients under 18 and found a decrease in opioid prescribing rates from 2006-2010 to 2011-2015. Regional and demographic differences were observed, with higher rates among white patients and those aged 13-17, as well as lower rates among Medicaid recipients.
The 2018 Monitoring the Future survey found a dramatic increase in teen vaping, with over 1 in 10 eighth graders and nearly 20% of high school seniors using nicotine vapes. Meanwhile, opioid misuse has dropped to record lows, with only 3.4% of 12th graders reporting past-year use.
A recent study published in Psychiatric Services found that over 12% of U.S. adults used benzodiazepines in the past year, with misuse accounting for nearly 17% of overall use. Benzodiazepine misuse was strongly associated with opioid and stimulant misuse, highlighting concerns about substance abuse.
A Stanford University School of Medicine study found that teens and young adults who receive their initial opioid prescriptions from dentists are at increased risk for opioid addiction in the following year. The study, which examined nearly 15,000 patients, found that those who received dental opioid prescriptions were more likely to c...
A study from the University of Eastern Finland found that one in five people with Alzheimer's disease use benzodiazepines and opioids concurrently. Prolonged use was linked to lung diseases, osteoporosis, and fractures.
A study found that 73% of drinking occasions occurred at home, while only 9% were at restaurants or bars. Drinking at home was rarely associated with driving after drinking or impaired driving, but still led to substantial numbers of drunken driving events.
Inhalant abuse is a growing concern among teens, particularly those from disadvantaged backgrounds, with up to 125 deaths per year in the US. Deodorant spray contains butane, which can be toxic when inhaled.
Research with mice suggests exercise strengthens resolve against drug addiction by changing peptide levels in the brain. Re-exposure to drug-related cues affects exercise and sedentary mice differently.
A study of older primary care patients found that hospital admission significantly increases the risk of inappropriate prescribing. The research highlights the need for better coordination of care to reduce medication-related harms.
A new study finds significant variation in opioid prescription rates and child removal rates among states, with some states experiencing a positive association between the two.
The Society for Neuroscience presents Dr. Michael Bruchas with the Jacob P. Waletzky Award, recognizing his research on stress biology and opioid signaling in drug addiction. His work has advanced our understanding of neural circuits and cell biology critical to developing new treatments.
Students from lower-income neighborhoods who attended top-performing Los Angeles County high schools were less likely to abuse marijuana. Attending one of these schools was linked to lower marijuana use, fewer peers abusing drugs, and improved academic performance.
A new study in fruit flies reveals that just a few drinks of alcohol can change how memories are formed at the fundamental molecular level. The research found that alcohol hijacks a conserved memory pathway and changes the proteins expressed in neurons, forming cravings.
A new drug test developed at the University of East Anglia can detect four classes of drugs in traces of sweat found in a fingerprint. The Intelligent Fingerprinting Drug Screening System enables rapid detection of amphetamines, cannabis, cocaine, and opiates from a single fingerprint sample.
A recent study found that at-risk teens and young adults are not being tested for hepatitis C, a serious liver infection, despite their risk of contracting it. The study, which analyzed data from over 250,000 youth, suggests that current guidelines underestimate who is at risk for the infection.
Psilocybin researchers propose moving the substance from a Schedule I classification to Schedule IV due to low potential for abuse and harm. This move would facilitate clinical trials and minimize logistical hurdles.
A modified form of blebbistatin appears to be effective in preventing cravings and relapse in people with substance use disorders, including those using multiple drugs. The compound works by breaking down memories linked to methamphetamine use, offering a novel approach to treating addiction.
Researchers at the University of Chicago Medical Center have developed a novel gene therapy approach that protects mice from lethal cocaine doses and reduces drug-seeking behavior. The therapy involves modifying skin grafts to quickly degrade cocaine and has shown promise in preventing addiction and overdose.
Researchers found ADHD patients had a higher risk of developing Parkinson's and Parkinson-like diseases than non-ADHD individuals, especially those prescribed stimulant medications. The study suggests that the long-term health effects of ADHD and its treatment remain understudied.
The study found that more than half of Americans misused their prescription drugs in 2017, with a surge in heroin and fentanyl misuse among patients with substance use disorders. The report also highlights the growing trend of gabapentin misuse and dangerous opioid combinations.
The study examines the prevalence and types of psychoactive substances used in Albania, revealing a significant increase in drug users since 2012. Cannabis is the most commonly used substance, particularly among young people, while heroin and cocaine also show notable usage.
Researchers at Wake Forest School of Medicine discover a safe and non-addictive pain medication called AT-121, which suppressed addictive effects of opioids and produced morphine-like analgesic effects. The compound also blocks abuse potential of prescription opioids like buprenorphine, offering hope to treat pain and opioid abuse.
A new report highlights the complexity of detecting and treating patients at hospital emergency departments for severe drug-related events. The study found that most patients tested positive for multiple substances, with some containing as many as six, complicating overdose diagnosis.
A researcher proposes changes to the MCDHS, including addressing use and abuse separately, collecting input from a broader range of stakeholders, and targeting substance-specific experts. This could lead to a more robust understanding of drug risks and improved public health outcomes.
A new study examines the scope of US state policies targeting drug use during pregnancy, revealing a trend towards punitive laws that limit access to treatment and services for pregnant women. Supportive policies are scarce, with only 12 states having such laws in place as of 2016.
A recent study found that benzodiazepine use is associated with a modestly increased risk of Alzheimer's disease. The research, conducted in the nationwide MEDALZ cohort, suggests that the threshold for prescribing these medications should be high due to their adverse effects and potential risks.
A recent survey conducted by the Center for Health, Work & Environment found that 13% of veterinarians in Colorado had seen a client intentionally injure or abuse an animal to obtain prescription painkillers. The study's results highlight the need for better training and surveillance to address opioid misuse among pet owners.
Researchers at NYU Abu Dhabi have developed a method to create microfluidic probes using 3D printing, which provides an effective and inexpensive technique for studying cancer cells. The new approach enables scientists to fabricate probes that can deliver reagents in a localized manner, allowing for targeted cell culture and analysis.
A new poll by U-M/AARP National Poll on Healthy Aging reveals that 74% of older adults support limiting opioid prescription amounts, while many struggle with safe storage and disposal of unused pills. The findings highlight the need for better counseling and resources to combat the opioid epidemic among this critical demographic.
New research reveals that gut hormones play a crucial role in addiction treatment, with ghrelin and GLP-1 analogs showing promise in reducing cravings. The study suggests that medications affecting these hormones could be repurposed to help manage drug craving and relapse.
Researchers at the University of Texas Medical Branch developed a treatment that reduces drug-seeking behaviors in rats by restoring serotonin signaling. This finding offers new hope for treating drug addiction and related health issues such as depression and schizophrenia.