Articles tagged with Drug Abuse
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Researchers at NYU Abu Dhabi have developed a new technique to preserve human cells using filter paper, offering advantages over traditional methods. The method requires less storage space and allows for easy loading and efficient freezing of cells, with viability rates comparable to conventional methods.
Researchers found that opioid dependence leads to permanent neuro-adaptations in the central nucleus of the amygdala, affecting pain transmission and GABA receptor activation. Normalizing nociceptin levels resulted in reduced opioid consumption, suggesting the peptide as a promising target for opioid use disorder treatment.
A study found that one in 18 physicians received pharmaceutical marketing for stimulant medications, often in the form of food or beverage. The study suggests that subtle marketing tactics may contribute to the increasing prescribing and misuse of these medications.
The U-MATTER program uses a deflection approach, directing people with opioid use disorders towards treatment and services. The initiative has seen positive outcomes, including 71 individuals receiving full clinical intake assessments and 40 committing to long-term treatment.
A study of over 4 million Medicaid claims records found that less than a third of adolescents and young adults who survived nonfatal opioid overdoses received timely follow-up addiction treatment. Only 1 in 54 youths received standard-of-care counseling and medications recommended by the American Academy of Pediatrics.
Research from University of Pennsylvania and Georgetown suggests drug-associated mortality is double the initially reported number. Drug use decreased life expectancy after age 15 by 1.4 years for men and 0.7 years for women, with West Virginia and other states experiencing high rates.
A new study found that Medicaid expansion was associated with a six percent lower rate of total opioid overdose deaths, as well as lower rates of death involving heroin and synthetic opioids. However, unexpectedly, an 11 percent increase in methadone overdose mortality was observed with Medicaid expansion.
The Geographic Variation in Addiction Treatment (GATE) study aims to identify factors influencing opioid medication use among individuals with opioid use disorder in the criminal justice system. The study will investigate how personal networks, structural factors, and geographic location shape treatment decisions.
A study published in Drug and Alcohol Dependence found that federal data undercounted overdose deaths caused by opioids and cocaine, with benzodiazepines underreported by 45% and amphetamines by 17%. The study suggests that the use of different reporting methods may be contributing to the disparity.
A study by researchers at UC San Francisco found that fewer than half of California pharmacies provided correct disposal instructions for antibiotics and opioids. Only 10% followed the FDA's recommended takeback programs. Improving disposal practices requires better education and expanded programs to ensure patient safety.
A recent study found that only 11% of California pharmacies have a drug take-back program, and even fewer provide accurate information on safe disposal methods. The lack of clear guidelines can lead to misuse and accidental poisonings, highlighting the need for improved education and resources.
A University of Michigan study found that prompt disposal of leftover medications improved when parents received a disposal packet and tailored online messages. The study suggests that easy disposal and risk education can significantly reduce the number of parents keeping leftover opioids for their children.
Clinicians are advised to screen, counsel and treat youth for vaping using well-studied models and youth-friendly terminology. The guidelines emphasize the importance of identifying relapse, providing positive reinforcement and revisiting treatment plans for effective cessation.
The 2019 Monitoring the Future (MTF) survey found that vaping of marijuana has more than doubled in the past two years, with past month use nearly tripling. Daily marijuana vaping also increased, reported at 3.5% among 12th graders. Overall, marijuana remains the most commonly used illicit drug by adolescents.
A national study found a significant rise in teens taking and overdosing on benzodiazepines, commonly prescribed anxiety medications. The rate of exposure among adolescents increased by 54% between 2000 and 2015, with nearly half of all reported exposures documented as intentional abuse or misuse.
Researchers at UCSF-Kaiser Permanente found that primary care patients with 'unhealthy alcohol use' were 15% more likely to take benzodiazepines than moderate drinkers and nondrinkers. This increased risk was associated with a higher likelihood of overdose, accidents, falls, and exacerbation of psychiatric conditions.
Researchers at Stanford University School of Medicine have identified a specific brain chemical, serotonin, responsible for the social behavior-enhancing effects of MDMA. The study suggests that novel treatments targeting this pathway may alleviate symptoms of psychiatric disorders marked by social awkwardness and withdrawal.
In an effort to curb opioid misuse, Massachusetts physician assistant programs have adopted a cross-institutional partnership to ensure safe prescribing practices. The initiative aims to educate students on the prevention and management of prescription drug misuse, following a consensus-building process among nine PA programs.
A new UCLA-led study suggests chronic opioid treatment may raise the risk of post-traumatic stress disorder (PTSD) in individuals who are likely to experience severe emotional stress. Researchers found that mice given morphine before and after a traumatic event showed enhanced fear learning, indicating increased PTSD susceptibility.
A recent study highlights a 'worrying' increase in misuse of gabapentin and baclofen medications in the US, coinciding with a decline in opioid prescriptions. The analysis found significant rises in intentional suspected suicide attempts and hospital admissions related to these non-opioid medications.
A new study found that cancer survivors are at risk of developing opioid addictions, with rates varying by cancer type and patient history. The research highlights the importance of identifying patients at risk of opioid-related problems to provide alternative pain management strategies.
A new study from Florida State University found that ketamine can decrease alcohol consumption in male rats with high-alcohol intake, with the effect lasting for at least three weeks. This discovery offers a promising tool in treating depression and potentially reducing alcohol use disorder in men.
A new study by Emory University researchers found a nearly 15% increase in drug abuse treatment admissions and a 6% increase in overdose deaths since Craigslist's founding. Online platforms like Craigslist provide anonymity, driving previously unaffected populations into the market.
A single dose of intravenous ketamine was found to have relatively mild and short-lasting side effects in patients with treatment-resistant depression. The most common side effect was feeling strange or loopy, which peaked within an hour and resolved within two hours.
The Erythroxylum genus has been stigmatized due to its association with cocaine, but a new review article reveals its potential use in traditional medicine and modern medicine. The genus encompasses over 230 species, including E. coca, which has been used for thousands of years.
Researchers found that patients who stopped using meth experienced a 43% improvement in their heart's pumping ability, while those who continued to use the drug saw a 4% worsening. These findings suggest that addressing meth abuse can lead to significant improvements in heart failure treatment.
A new USC study reveals that mint is the most popular flavor among U.S. teens who vape, contradicting previous studies that linked fruit flavors to teen vaping. The findings cast doubt on the effectiveness of JUUL's voluntary product removal and federal regulations aimed at reducing youth vaping.
A recent study by NYU College of Global Public Health found that construction workers are the most likely profession to misuse opioids and cocaine. The researchers analyzed data from over 293,000 participants and discovered a strong link between physical demands of construction work and substance use.
Opioid overdose deaths in Connecticut more than doubled between 2012 and 2018, driven by increased use of multiple drugs. The study found that fentanyl-related deaths often involved at least one other drug, highlighting the need for new prevention and intervention strategies.
Researchers discovered a link between SETD1A gene mutations and schizophrenia risk in mice. Restoring the gene's function reversed behavioral and neuronal abnormalities, suggesting potential treatment strategies.
Researchers aim to develop a new compound, SBI-553, to treat opioid-use disorders with limited effectiveness. The compound has shown promise in preclinical testing, reducing addictive behaviors and improving safety profiles.
The Temple research team will investigate the mechanism by which HIV infection leads to greater sensitivity to pain and reduced effectiveness of opioid therapeutics. The study aims to understand how chronic inflammation promotes cross-desensitization of opioid receptors, resulting in elevated pain sensitivity.
A new study suggests that up to 90% of people in treatment for addiction have a history of alcohol overdose, often combined with other substance use. The study's findings emphasize the importance of addressing alcohol use as a risk factor for severe overdose events.
The National Institutes of Health (NIH) has awarded McLean Hospital nearly $1 billion to address the national opioid crisis through scientific solutions and evidence-based treatments. The hospital will explore ways to improve outcomes for patients using medications like buprenorphine and naltrexone to treat opioid use disorder.
The prevalence of past month nicotine vaping among teens has more than doubled since 2017, reaching alarming rates. The National Institute on Drug Abuse reports that 25% of 12th graders and 20% of 10th graders now vape nicotine within the past month.
A study found that young adults in the US report high rates of non-medical prescription drug use, binge drinking, and illicit drug use. Researchers recommend a multilevel approach to address potential harms related to polysubstance use throughout the life course.
A new study suggests that opioid treatment medications can increase the number of teens who remain in treatment and decrease their opioid use. Medications like methadone, buprenorphine, and naltrexone have shown promise in treating severe opioid use disorder in adolescents.
Scientists at Scripps Research Institute have identified brain cells that suppress drug cravings, which could lead to improved addiction treatments. The discovery sheds new light on how the brain responds to environmental cues that prevent relapse, providing hope for more effective medicines in the future.
A new study by Weill Cornell Medicine found that states with comprehensive prescription drug monitoring program mandates saw a 8.92% reduction in opioid prescriptions and 17.75% fewer emergency department visits compared to those with weak or no mandates.
A new medication that boosts endocannabinoids in the brain shows promise to treat post-traumatic stress disorder (PTSD) by enhancing fear extinction learning. The study found that participants who received the FAAH inhibitor remembered fear extinction memory better, offering hope for a new treatment.
Researchers found strong evidence that cannabis alleviates pain, with users experiencing a significant drop in pain suffering after consumption. The study highlights the potential of cannabis as a safe and effective alternative to opioids for treating chronic pain.
A new study published in the American Journal of Public Health found that 88% of past-12-month prescription opioid users used the drugs only as prescribed by a physician, while 4% misused them. Prescription-only misusers were more likely to be depressed and have higher rates of substance use disorder and benzodiazepine misuse.
A study by UMass Amherst researcher Elizabeth Evans found that individuals who perceived buprenorphine as unacceptable were least likely to use the medication during follow-up. The study also identified common reasons people disliking buprenorphine, such as negative physical reactions and side effects.
A team of researchers at Scripps Research Institute has discovered an anti-opioid pathway that counteracts the effects of opioids on neuronal firing. The discovery could lead to the development of new pain medications with less potential for abuse and overdose.
Researchers at Cornell Tech developed a new clinical model to respond systematically to digital threats against victims of intimate partner violence. The model includes a technology assessment questionnaire, technograph diagram, and ISDi spyware scanning tool to help counselors pinpoint online abuse and protect victims' safety.
Researchers created a community-focused drug abuse monitoring system called DrugTracker, which analyzes social media posts and geospatial data to detect trends and changes in the landscape. The system helps organizations identify drug abuse risk behaviors and allocate resources effectively.
A recent study found that nearly 11% of high school seniors reported misusing prescription drugs in the past year, with 44% relying on multiple sources. This increases the risk of substance use disorders and other issues.
The practice of microdosing psychedelic drugs to enhance mood and productivity lacks robust scientific evidence. Despite reports of positive experiences, the team presents a lack of controlled studies, uncertain doses, and safety concerns, highlighting the need for rigorous research.
Research found that more physicians receiving industry money prescribed brand-name gabapentin, increasing concerns about its potential for abuse. Gabapentin prescriptions have tripled in the US since 2002.
Most large health systems have active stewardship programs to prevent opioid misuse, with pharmacists playing a key role in detection and strategy development. Pharmacists also play a major role in drug therapy monitoring and patient education.
A new poll suggests that many grandparents are storing their medications in easy-to-reach places, posing a risk of accidental poisoning or intentional misuse. The poll found that nearly 80% of grandparents keep their medications in the same place as usual when their grandchildren visit, and 72% store them in purses or bags.
A University of Cincinnati researcher is conducting an omics analysis of synthetic opioids and HIV to better understand their interactions. The study aims to develop new therapies for individuals battling addiction and living with HIV.
A new study found significant issues with non-medical use of alprazolam in the UK, particularly among younger adults. The estimated national prevalence of lifetime and recent use was 0.32% and 1.30%, respectively.
Research suggests that most people initiate opioid use through recreational means due to peer influence, rather than medical prescriptions. The study found that 56% of interviewees began using opioids recreationally first.
Researchers found US dentists prescribe 37 times more opioids than UK counterparts in 2016, a peak year in the US opioid crisis. The study emphasizes the importance of adopting national guidelines for treating dental pain and promoting judicious opioid prescribing among US dentists.
A recent study shows a dramatic rise in opioid overdose deaths among American veterans, mainly caused by heroin and synthetic opioids. The research emphasizes the need to provide care to veterans with non-prescription opioid use disorder, independent of prescription opioid use.
A recent study published in the Journal of the American Dental Association found that patients who received comprehensive oral care as part of their substance use disorder treatment had a significant increase in completing their treatment programs. The results show that participants who underwent FLOSS (Facilitating a Lifetime of Oral ...
A 14-year-old high school student developed a novel technology to prevent opioid pill tampering, earning the top prize at the Intel International Science and Engineering Fair. The project, called Tampr-X, uses a protein matrix-based substance that discourages crushing or melting for misuse.
Researchers at the University of Virginia have identified a possible new drug target for reducing chronic pain and inflammation. A naturally occurring enzyme called diacylglycerol lipase-beta (DAGL?) has been found to produce chemical signals that control inflammation, making it a viable target for non-addictive pain relief.
A new study found that weight loss medications are extremely lowly used among eligible veterans, with only about one percent receiving treatment. Barriers such as insurance coverage, age, and ethnicity drive underuse of these medications, highlighting the need for additional research to better understand obstacles.