A new study reveals that genes from soil bacteria were transferred to algae through horizontal gene transfer, allowing early life to move from water to land. This process, known as terrestrialization, marked a crucial event in the evolution of life on Earth.
New research from Ohio State University finds a fundamental flaw in Bluetooth Low Energy devices' communication with mobile apps, leaving them vulnerable to fingerprinting attacks and unauthorized access. The study identified over 5,800 Bluetooth devices, with 94.6% of them able to be 'fingerprinted' and 7.4% vulnerable to hacking.
Researchers analyzed DNA data from 513 pairs of males living in Belgium and the Netherlands to explore paternity questions over 500 years. The study found that EPP events were more common among lower socioeconomic classes and densely populated cities.
Researchers found that parents of children with CHD want individualized, formal psychosocial support to mitigate stress and improve long-term outcomes. The study outlines ways to optimize mental health for parents and supports positive child outcomes.
Researchers found increased variability in electrical 'resetting' between heartbeats in people with HIV, linked to virus levels and increasing risk of sudden cardiac deaths. The study suggests that this measure could be used to assess risk and identify ways to intervene.
The study reveals that bacteria have multiple oxidases, with cytochrome bd oxidase playing a crucial role in energy production and stress protection. The novel findings provide insights into the development of new antimicrobials targeting pathogens.
Recent advancements in wearable and implantable hemodialysis devices have the potential to revolutionize treatment for patients with kidney failure. These devices aim to provide a more patient-friendly alternative to traditional hemodialysis, allowing patients to lead healthier lives.
Researchers at Saint Louis University have developed a way to program built-in controls in microfluidic networks, enabling the creation of miniaturized chemical laboratories on a chip. This technology has potential applications in point-of-care diagnostics, field research, and even space exploration.
A Northwestern University study combines 3D climate modeling with chemistry to explore the habitability of planets around M dwarf stars. The research finds that only planets orbiting active stars lose significant water to vaporization, making them less likely to sustain life.
Integral Molecular to receive up to $5.5 million from NIAID to study antibody responses to Zika, Marburg and EEV viruses. The company's Shotgun Mutagenesis technology will aid in the discovery of vaccines and therapeutics against these deadly viruses.
The Singapore Diabetes Study in Nephropathy and other Microvascular Complications (DYNAMO) aims to reduce DKD prevalence in Singapore by 30% over five years. The study, led by Professor Thomas Coffman, uses a multi-pronged approach to better understand the disease biology and risk factors behind DKD.
Researchers from MIPT explored microRNA interactions with mRNA in two human cell lines, finding that microRNA does not strongly regulate all genes and its regulation potential does not directly depend on its expression level. The study also identified differences between microRNA interactions in the two cell lines.
A new optical switch developed by the NIST team can route light at speeds of 20 billionths of a second, making it ideal for quantum computing and high-performance computing. The device uses a miniature racetrack to redirect light signals with low signal loss.
Researchers at Rice University developed bottlebrush copolymers to refine surface coatings, making them more waterproof or conductive. The polymers' migration to top and bottom of thin films can effectively decouple properties of bulk coating from exposed surfaces.
UK researchers found significant increases in spring, autumn, and winter precipitation in upland areas, with winter increases consistent with national climate models. The study suggests caution is required when making assumptions on climate impacts based on climate models.
Researchers warn that Africa's Lake Victoria could dry up in the next 500 years due to climate change, posing a significant threat to 40 million people. The lake's water levels are projected to decline rapidly if temperature changes and precipitation patterns shift
Scientists at UCSF discovered that blocking the activity of MMP9 can prevent breast cancer from spreading to distant organs. The researchers found that MMP9 helps create a hospitable environment for cancer cells to form new tumors by remodeling healthy tissue and transforming it into safe havens.
Researchers at FSU's High-Performance Materials Institute have developed a thin heat shield for high-speed aircraft using carbon nanotubes, known as 'buckypaper.' The material is lightweight, flexible, and durable, protecting the aircraft from intense heat while reducing weight.
Researchers found that typhoons and eutrophic surface sea waters may be significant sources of dissolved organic nitrogen (ON) in wet deposition. Approximately one-third of total ON wet deposition was attributed to the co-occurrence of intense events like typhoons and strong rainfall.
A new analysis finds that large drug manufacturers would still be the most profitable industry sector even with $1 trillion in lower sales. This is despite the pharmaceutical industry having among the highest profit margins and returns of any industry group. The researchers found that large drug companies could lose significant revenue...
Researchers have discovered that blocking MCL1 protein can eliminate melanoma cells more effectively, even in late-stage cancers. Combining MCL1 antagonist AZD5991 with existing treatments like vemurafenib has a 'double whammy' effect against cancer cells.
A new study conducted at the University of Georgia found that feelings of neighborhood pride and interactions with tourists influence residents' attitudes towards short-term vacation rentals. The study, which surveyed residents in Savannah, Georgia, suggests that well-designed regulations can foster support for these types of rentals.
A study published in Scientific Reports reveals the dopamine D2 receptor plays a crucial role in modulating Wnt expression and controlling cell proliferation, which may lead to new therapeutics for nephrology, endocrinology, and psychiatry. The findings also have implications for the development of precision medicine.
Researchers successfully simulated every atom of a light-harvesting structure in a photosynthetic bacterium, revealing how it converts sunlight into chemical energy. The study confirms physics drives biology at the atomic scale, informing future studies of complex energy-generating organelles.
Recent studies found that smokers and hypertensive individuals have better chances to survive subarachnoid hemorrhage than non-smokers and those with normal blood pressures. However, a new Finnish study included patients who died before reaching hospital wards and showed the opposite - that these groups are more likely to die from brai...
A global study reveals that bicarbonate use among aquatic plants is linked to local geology and concentration levels. Many freshwater plants have evolved to use bicarbonate for photosynthesis due to low dissolved CO2 in water.
Researchers analyzed over 65 years of records and data on hatchery-origin Chinook salmon in the Salish Sea, finding that larger fish are being released but still vulnerable to predators. The study suggests a narrow two-week window of release may lead to 'boom or bust' dynamics, affecting sustainability.
Researchers at Children's National Hospital aim to use mesenchymal stromal cells collected from bone marrow to promote brain growth and repair in newborns undergoing cardiac surgery for congenital heart disease. The NIH-funded trial seeks to determine the safety of this treatment and set the stage for a Phase 2 efficacy trial.
The Texas Advanced Computing Center will develop a meta-portal to provide access to analytics tools and data sets for researchers studying the biological characteristics underlying acute-to-chronic pain transition. Researchers aim to identify biomarkers that can predict chronic pain for medical and public health use.
A new study projects that urban expansion will trigger 'extra' warming due to the urban heat island effect, increasing extreme heat risks for half of the world's future urban population. The study forecasts temperatures may rise up to 3 degrees C in some locations, particularly in tropical regions.
A new study reveals that intestinal stretch sensors uniquely stop hungry mice from wanting to eat, contradicting long-held assumptions about how we feel full. Researchers mapped the molecular and anatomical identities of vagal sensory cell types innervating the stomach and intestine, discovering that these stretch receptors are more po...
Researchers discovered that SNAP, a nitric oxide donor, overcomes TMZ resistance in glioblastoma multiforme (GBM) cells by reducing MGMT protein stability. This finding offers a potential strategy to improve treatment outcomes for patients with GBM.
A new study published in Scientific Reports found that short-term sugar consumption increases the risk of colitis and worsens symptoms in mice. Madsen's research revealed that high-sugar diets feed 'bad' microbes, leading to inflammation and immune system problems.
Researchers found that prostate cancer bone metastases produce high levels of TGF-β, which crowds out helpful T cells needed for effective treatment. Combining anti-TGF-β with checkpoint inhibitors may reverse resistance and improve outcomes.
A new solar power generator prototype developed by Ben-Gurion University of the Negev and US research teams will be deployed on a NASA flight to the International Space Station. The compact system could provide unprecedented watt per kilogram of power, critical to lowering costs for private space flight.
Researchers found that participants who demonstrated a game face showed improved performance in cognitive tasks, such as completing a black-and-white mandala puzzle, with an average gain of 20 percent. Additionally, the study found that game face may aid in better recovery from stress after physical challenges.
A new study found that even slight impairments in hearing can lead to decreased cognitive function, with the largest decline occurring in those whose hearing was just starting to become impaired. The researchers suggest that treating hearing loss could reduce dementia incidence by up to 9%.
Researchers successfully produce pure polynitrogen by zapping sodium azide with a jet of plasma in liquid nitrogen, opening a new avenue for stable production. The substance is stable at atmospheric pressure and temperatures up to -50 Celsius.
Scientists at Vienna University of Technology have developed a new thermoelectric material with a ZT value of 5 to 6, generating electrical current very efficiently from temperature differences. This enables sensors and small processors to supply themselves with energy wirelessly.
Research highlights the disproportionate impact of diabetes on women, with a higher risk of cardiovascular death and heart failure compared to men. Healthy lifestyle habits and glucose-lowering treatment are crucial in preventing these complications.
The J.M.K. Innovation Prize recognizes 10 non-profit and mission-driven organizations addressing pressing challenges through social innovation, providing up to $175,000 in funding over three years. The award aims to shine a spotlight on innovators tackling issues in under-resourced parts of America.
A new study by Yale researchers found that physicians rate EHR systems poorly, with an average score of 45, leading to increased frustration and burnout. The study suggests that the steep learning curve and lack of intuitive design contribute to this outcome, affecting specialties such as dermatology and general surgery.
A pilot study at Children's National Hospital found that direct-to-patient telemedicine cardiology follow-ups can safely reduce the need for in-person visits. The virtual care approach enabled doctors to extend their reach and improve patient care without unnecessary transport or lost time from work.
Researchers at FEFU developed a method to synthesize biologically active derivatives of fascaplysin, a compound found in sea sponges. The new compounds, including 14-bromoreticulatine and 3,10-dibromofascaplysin, show selective effects on cancer cells, particularly Pseudomonas Aeruginosa bacteria and human prostate cancer cells.
Researchers at NTU Singapore found that gut microbes can alter the ageing process by increasing neurogenesis and regulating energy metabolism. The discovery highlights a potential food-based treatment to slow down ageing, using butyrate produced by microbial fermentation of dietary fibres.
A team of scientists used satellite data to augment measurements of a 2017 North Korean nuclear test, estimating its yield to be between 245 and 271 kilotonnes. The study demonstrates the value of space-borne InSAR data for measuring underground nuclear tests with greater precision than conventional seismic methods.
A study by UMass Amherst researchers found that the 2008 parity law increased Medicaid acceptance rates for substance use disorder treatment centers by more than 10 percentage points. The increase was attributed to an 8.4% boost in 2009, with higher acceptance rates in the Northeast and lower rates in the South and Southeast.
Chemists at the University of Tokyo mapped an artificial molecular self-assembly pathway that forms a spherical cage and an ultrathin sheet, exhibiting primitive qualities of a 'smart' material. The research team hopes to design molecules that can self-assemble and reorganize independently under environmental conditions.
Researchers at TGen and USC have diagnosed two sisters with progressive spastic paraplegia due to an extremely rare genetic variant in the AP4S1 gene. The team used advanced precision medicine techniques, including whole-blood mRNA sequencing, to identify the variant, which had been previously overlooked.
New research reveals that chromatin dynamics regulate the entire herpes virus genome's expression during infection. The discovery sheds light on the interplay between the virus and host cells, potentially leading to more effective treatments.
A Rutgers University study found that women exposed to stress and plastic additives during late pregnancy are at increased risk of premature birth. The research suggests that the third trimester is a critical window for this risk, with higher levels of phthalates in urine and reported stress during pregnancy also linked to preterm births.
This study analyzes the performance of Russian and foreign- owned banks from 2004 to 2015, finding that state-owned banks excel during economic crises but lag behind in profit efficiency. In contrast, foreign-owned banks thrive in stable periods, thanks to better management practices.
A new study found that certain urban areas have significantly higher rates of heroin use among high school students, with Latina and white girls in Duval County, Florida, showing the highest figures for non-medical prescription opioid misuse. The findings underscore the need for tailored services to address adolescent opioid abuse.
A new study by Norwegian University of Science and Technology finds that children who can recognize 19 letters are more likely to break the reading code. Parents can support their children's reading development by practicing letter sounds and encouraging independent reading.
Magnetic reconnection near the solar surface generates solar spicules, which channel hot plasma into the corona. The study reveals that energy released from magnetic field realignment triggers enhanced spicular activity, causing local heating of the upper atmosphere.
Researchers found that inhibiting the integrated stress response (ISR) reversed memory deficits in a mouse model of Down syndrome. The study suggests that modulating ISR networks may help treat Down syndrome and other disorders resulting from disruption of this network.
A study found that bots are more successful in certain human-machine interactions when they hide their non-human identity, but cooperation rates decrease when transparency is required. This has implications for the use of bots in help desks and other scenarios where efficiency is key.
Researchers developed a new systematic analysis method that uses machine learning to integrate computational model with experimental results, providing atomic-level data on carbon surface chemistry. This allows for better understanding of carbon-based materials without human-induced bias.
Researchers at Princess Margaret Cancer Centre have identified new protein targets for drug development against prostate cancer by analyzing noncoding DNA regions. These regions, previously thought to be 'junk' DNA, were found to harbor important regulatory elements that determine gene expression.
A pre-clinical study suggests that bisphenol-s (BPS) and bisphenol-f (BPF), structural analogues of bisphenol-a (BPA), have less impact on heart electrical function, making them potentially safer for vulnerable populations. This finding could lead to the development of alternative medical products.
Researchers developed a promising methodology for monitoring postoperative abdominal aortic aneurysm progression using CTA image registration and biomechanical strain analysis. The approach correlates with patient long-term prognosis, offering a new tool for assessing post-EVAR risk of rupture.
A team of astronomers used ALMA to study the structure of dense gas in N159, a bustling star formation region in the LMC. The observations found fan-shaped filaments of gas extending to the north with pivots in the southernmost points, similar shapes and ages of baby stars in two regions separated by 150 light-years.
NASA's AIRS instrument detected coldest cloud top temperatures as cold as minus 63 degrees Fahrenheit around Fengshen's center, suggesting a strong storm. Forecasters expect Fengshen to continue strengthening and reach typhoon status, with maximum sustained winds near 65 mph.
A Michigan State University study found that intelligence was the strongest predictor of skill acquisition in beginner pianists, followed by music aptitude. In contrast, growth mindset had little impact on piano performance.
The Suomi NPP satellite identified strong storms in Tropical Cyclone Kalmaegi using infrared light, with cloud top temperatures as cold as minus 80 degrees Fahrenheit. Wind shear is preventing the storm from consolidating, allowing it to maintain a tropical depression status.
Researchers developed a faster and stronger rabies vaccine by adding B cell activating factor (BAFF) to an existing inactivated virus-based vaccine. This new approach enhanced the immune system's response, increasing virus-neutralizing antibodies quickly and significantly.
The National Science Foundation grant will support the development of an open knowledge network to provide better information for agencies managing wildfires, water quality, and biodiversity conservation. The team aims to create automated methods to collect and share relevant information, improving decision-making processes.
A recent study found that 17% of sexual minorities experienced discrimination in the previous year, with higher rates among males and older adults. The researchers aim to raise awareness about the need for continued work to reduce discrimination and promote inclusive policies.
Researchers developed a computational model, Combined Essentiality Scoring (CES), to accurately identify essential genes in cancer cells. The model predicts cancer essential genes with higher accuracy than existing methods and suggests two predicted genes as potential drug targets for breast cancer and leukemia.
Researchers demonstrate that thin films of amorphous aluminum oxide glass can be permanently bent and pulled under high stress without breaking. The flawless material's high plasticity is linked to its density, with key criteria needed to identify other ductile oxide glasses.
Patients with inflammatory bowel disease are more likely to develop Parkinson's disease due to shared underlying inflammation. While the risk is small, early detection and intervention may be crucial in slowing or stopping PD progression.
Researchers tested a two-step task to train people to rely on goal-oriented behaviors, but found no substantial change in behavior or brain activity. The study suggests that the task's methodological drawbacks make it unsuitable for training purposes.
Researchers have solved a critical piece of the puzzle by showing how insulin interacts with its receptor at a second binding site. This new understanding will allow researchers to design improved treatments for insulin-related disorders, such as diabetes.
A new study published in Blood Advances found that patients receiving multidisciplinary, holistic evaluation before undergoing transplantation have improved outcomes and survival rates. The team-based approach coordinated recommendations from various care providers and created individualized treatment plans.
A new study reveals a 16% decline in the relationship between binge drinking and depressive symptoms among high schoolers from 1991 to 2018. The decline is even more pronounced among girls, with a 25% decrease in the association.
A new report reveals that Americans have consistently trusted scientists over the past several decades, with a majority expressing confidence in scientific institutions. Despite concerns about science becoming partisan, recent surveys show stable trust levels, particularly among Democrats and Republicans alike.
Researchers have developed a new method to observe changes in molecular chirality during chemical reactions in real time. They used femtosecond laser pulses with tailor-made polarization to follow the disappearance of chirality after bond breakage.
A new study led by Australian National University researchers casts doubt on China's reported organ donation numbers, suggesting they may be falsified using a simple mathematical formula. The study found anomalies in the data that are difficult to explain, raising the possibility of deliberate manipulation.
Researchers developed nanoparticles that can deliver immunostimulants via inhalation to induce systemic immune response against lung cancer. The treatment converted cold tumors to hot, immune-responsive tumors and showed significant regression of tumors in both lungs and prolonged survival of mice.
Researchers identified genetic variations in non-coding enhancer regions of specific brain cell types, such as microglia, which may play a role in disease risk. The study provides new insights into how genes are regulated in individual cell types and has significant implications for understanding neurological conditions.
Researchers found that racialized sexual discrimination emerges in online communities and mobile apps, perpetuating stereotypes and shame among men of color. A new scale developed to measure its impact may help better understand the well-being of ethnic minorities.
Using waste heat helps reduce the cost of producing hydrogen, a key step towards cleaner energy. Researchers developed an approach that uses low-grade waste heat to produce hydrogen, with potential for lower production costs and increased efficiency.
A Yale professor and his team discovered an abrupt 60-year megadrought that led to the collapse of the Neo-Assyrian Empire. The drought weakened the empire's agricultural base, allowing neighboring forces like the Babylonians to conquer Nineveh in three months.
A Norwegian University of Science and Technology study found that increasing cardiorespiratory fitness can halve the risk of getting dementia. Participants with poor fitness in the 1980s who improved it within a decade lived two years longer without dementia.
A recent study found that the autocatalysis of water enhances the formation of COOH intermediate through proton transfer, accelerating CO generation while hindering methanol synthesis. The research also revealed that high initial partial pressure of water inhibits CO2 conversion due to excessive OH* coverage.
A new study found that genetic variants influence the benefits of broccoli on kidney health, suggesting tailored dietary interventions. Individuals with a specific gene variant (GSTM1) who consume cruciferous vegetables may experience improved kidney function.
Researchers have developed a compact, room temperature, widely tunable terahertz laser that outperforms existing sources. The laser offers high power and wide tuning range in a robust design, unlocking new applications in science and technology.
The Erythroxylum genus has been stigmatized due to its association with cocaine, but a new review article reveals its potential use in traditional medicine and modern medicine. The genus encompasses over 230 species, including E. coca, which has been used for thousands of years.
A new study published in the American Journal of Public Health estimates that 171,900 Canadians injected drugs in 2016, with a 30-per-cent increase from 2011. The study also found wide variations in service coverage across provinces and territories.
A genome-wide gene deletion study on malaria parasites identified hundreds of new targets for disease control. The study, led by the University of Bern, used a malaria mouse model to systematically screen the parasite's genome and identify essential metabolic pathways.
A global team of computer scientists developed Write-A-Video, a new tool that generates videos from themed text. Novice users can produce quality video montages in a simple and user-friendly manner without requiring professional skills.
A KAIST research team has developed a gallium-based metal complex enabling the rapid chiral analysis of alcohols using nuclear magnetic resonance spectroscopy. This new method can determine enantiomeric excess within minutes, benefiting researchers in organic chemistry and the pharmaceutical industry.
Researchers examined over 500 vaccine-related ads on Facebook and found that a small group of anti-vaccine ad buyers targeted specific audiences, while pro-vaccination ads were often rejected due to Facebook's policies. The study highlights the need for social media platforms to balance free speech with public health concerns.
A team of researchers from Ben-Gurion University has developed an innovative approach to kill mosquito larvae by delivering bacteria into the male mosquito's gut during mating. The method uses natural bacteria that produce a toxin only lethal to mosquito larvae, resulting in a targeted and effective biological pest control solution.
New research reveals MICU1 protein's role in maintaining muscle size and function, repairing damaged fibers, and regulating calcium balance. Loss of MICU1 disrupts calcium uptake, leading to muscle fatigue, weakness, and atrophy, highlighting its potential as a therapeutic target for neuromuscular diseases.
A team of researchers identified protective antibodies against severe malaria in children, paving the way for a potential vaccine. The discovery uses genomic sequencing and machine learning to pinpoint specific proteins and antibodies that provide immunity.
Researchers have developed a new multilayered complex that displays high-performance near-infrared electrochromism. The complex, prepared by layer-by-layer coordination assembly on metal oxide substrates, exhibits two reversible redox waves and excellent electrochromic performance with a contrast ratio of up to 56% at 1150 nm.
A new antibody treatment has shown promising results in a small pilot study, allowing participants with severe peanut allergies to eat a modest amount of peanut protein within 15 days. The treatment's effects lasted for up to 45 days, providing a potential breakthrough for food allergy treatments.
The grant will fund a conference and policy brief development to address the challenges faced by autistic individuals in the justice system. Autistic individuals are at increased risk of negative outcomes due to lack of understanding and inadequate support.
A new study found that nearly two-thirds of infants and almost all toddlers consumed added sugars in their daily diets, primarily in flavored yogurts and fruit drinks. The widespread intake points to a serious problem, as early eating patterns can lead to negative health conditions such as cavities, obesity, and elevated blood pressure.
Researchers have identified patterns of epigenetic molecules on sperm DNA that can indicate male infertility. A new diagnostic approach could provide doctors with a reliable method to screen men for infertility, saving couples time and effort in finding suitable treatment options.
A new study warns against a rush to exploit deep seafloor resources, emphasizing the importance of conservation of ecosystems. The international community is urged to develop a legal framework that considers the common heritage of mankind status, ensuring sustainable use of marine biodiversity.
Researchers at Arizona State University found that some aquatic plants depend on the landscape for carbon through bicarbonate extraction, not just atmospheric CO2. This discovery highlights the importance of understanding how freshwater ecosystems function and respond to environmental changes.
A new study by Anglia Ruskin University finds that crows in larger social groups have lower parasite loads and are healthier. The research reveals a correlation between sociability and health, suggesting that strong social bonds reduce stress levels and make crows less susceptible to parasites.
Researchers calculated that over 30 years, around 200,000 tonnes of micro rubber accumulated in Switzerland's environment. Tire abrasion is the primary source of micro rubber, responsible for 97% of particles released.
Research led by the Universitat Autonoma de Barcelona found that Alpine rock axeheads were a crucial component of pan-European exchange networks, with some rocks traveling over 1000 kilometres. The study's results suggest that the rocks' exceptional durability and resistance to friction made them highly valued for their production value.
Researchers found that linguistic similarity between the learner's first language and Dutch accounted for 50% of explained variance in learners' proficiency. This suggests that language instruction tailored to a learner's first language can be more effective, corroborating an important insight from research on teaching adults
Researchers at the University of Münster have developed a novel method to build three-dimensional scaffolds from flat aromatics using light. The method utilizes a photocatalyst to facilitate an energy-transfer catalyzed intramolecular [4+2] cycloaddition, resulting in the creation of dehydroisoquinuclidines and other valuable structures.
Researchers found that patients who received nudges had better adherence (80%) compared to those in the control arm. Nudges supported patient decisions without restricting options.
A new screening approach for retinopathy of prematurity (ROP) has been developed, adding slow weight gain to existing criteria. The method was tested in a large prospective study and found to correctly predict ROP cases while reducing unnecessary examinations by nearly a third.
A recent study found that providing more context about a drug's efficacy can improve physicians' knowledge but reduce enthusiasm for prescribing it. The researchers also discovered that company-sponsored information about off-label uses can increase prescription rates.
Researchers used CRISPR gene editing to study butterfly wing patterns, finding that similar patterns evolved through different genetic pathways despite shared environmental pressures. The study reveals the complex interplay between chance and history in shaping evolutionary outcomes.
Researchers found climate change and turf seaweed contributing to the transformation of seafloor landscapes, with shrub-like seaweed dominating lower areas. This shift could impact species habitats and the food web, specifically affecting mid-trophic level species like cunner.
Research in rats reveals that brain-wave bursts, like earthquakes, are necessary for healthy sleep. These non-equilibrium dynamics and criticality underlie sleep micro-architecture, governing spontaneous transitions between sleep stages.
Researchers at Baylor College of Medicine discovered that the Zika virus protein NS4A disrupts brain growth by hijacking a pathway that regulates the generation of new neurons. The study found that overexpression of Zika protein NS4A causes microcephaly in flies by inhibiting the function of ANKLE2, a cell cycle regulator.
Researchers at University of Queensland have discovered markers in blood that differentiate benign moles from melanoma, as well as detect cancer spread to other areas. The blood test may monitor very early signs of the disease, allowing for better screening of patients with eye naevi.
Researchers analyzed 1418 galaxies and found small ones spin differently than large ones. The alignment changes as galaxies collide and merge with others, gaining mass. The study offers insight into the deep structure of the universe and how galaxies form.
Researchers are studying brain aging and dementia in 500 individuals born in 1946, using detailed assessments and brain scans to identify risk factors. The goal is to develop better preventative health strategies and improve clinical trials.
A new economic study by USC researchers suggests that breakthrough treatments for wet age-related macular degeneration (wAMD) offer significant patient benefits and societal value. The treatments generate $5.1 to $8.2 billion in patient benefits, translating to $0.9 to $3.0 billion in societal value over three years.
UNC Lineberger researchers have discovered a method to identify triple negative breast cancer tumors that will respond to immunotherapy. The findings, published in the journal Cell, could help guide patients to the right treatments and lead to new approaches to make drugs work in cancers that don't initially respond.
Researchers suggest that exercising before, during, and after treatment, like NASA astronauts, could reduce muscle mass loss, bone demineralization, and heart problems. Cancer patients may benefit from a similar routine to counteract long-term side effects of treatments.
Researchers developed an image-processing algorithm to analyze satellite images of arctic ice floes, revealing long-term ocean movement dynamics. The technique improves understanding of sea ice transport, its interactions with ocean currents, and the impact on climate change.
Researchers at Eindhoven University of Technology have developed a new platinum-nickel catalyst that accelerates chemical reactions 20 times more effectively than traditional platinum-based catalysts. This breakthrough has significant implications for the storage and conversion of hydrogen, a promising source of sustainable energy.
A peer-reviewed commentary warns of widening HIV infection disparities among Hispanics/Latinos, with the highest increase seen in gay and bisexual men aged 25-34. The article advocates for targeted investment in stigma reduction, treatment accessibility, behavioral interventions, and community leadership engagement to address the crisis.
Researchers at Lehigh University's P.C. Rossin College of Engineering and Applied Science are designing a more efficient tidal turbine using a $250,000 NSF grant. They will test different fairing shapes in a water tunnel facility equipped with an active grid turbulence generator to reduce energy loss and increase renewable energy power.
Researchers found altered immune responses and sex-specific brain abnormalities in healthy pig offspring infected with Zika virus in-utero. The study suggests new strategies to prevent long-term effects of Zika infection.
Researchers have successfully created a new one-way street for light by cooling photons to a Bose-Einstein condensate. This process causes the light to collect in optical valleys from which it can no longer return, effectively irreversibly dividing the light beam. The findings could be of interest for future quantum communication.
The study estimates that preserving 270 million hectares of native vegetation yields Brazil USD 1.5 trillion per year in ecosystem services such as crop pollination, pest control, and water security. This research supports the importance of Legal Reserves and Permanent Conservation Areas in maintaining environmental services.
Scientists have developed a compact device that produces terahertz waves by spinning nitrous oxide molecules, offering precise control over wireless communication distances. The technology has the potential to revolutionize applications in radar, spectroscopy, and medical imaging.
New studies in Cell journal use Tara Oceans samples to assess plankton diversity, revealing a gradient of diversity along latitudes. Transcriptome study also explores microbial community gene expression and adaptations to environmental conditions.
The study found that T-DM1 resulted in a third of patients experiencing objective response and nearly 40% continuing treatment for at least six months. Patients with central nervous system metastases had shorter progression-free survival rates, highlighting the need for inclusion in randomized trials.
A team of researchers has revealed a new state of matter where Cooper pairs enable electricity to flow with some resistance. This finding challenges current theories and requires further investigation. The discovery was made using a technique that involves patterning a thin-film superconductor with arrays of tiny holes.
A new grant from the Foundation for Food and Agriculture Research aims to map the Asian longhorned tick's spread and provide farmers with mitigation strategies. The project involves a tick-surveillance network and will enhance awareness about the pest, empowering stakeholders to make informed decisions.
Scientists cultivate chemical reactions similar to those found on Earth, using a novel strategy to study the origin of life. The system appears to consume its raw materials, forming feedback loops and self-propagating networks.
A recent study found that mitochondrial damage-associated molecular patterns (mtDAMPs) are released by DCD hearts following warm ischemia, correlating with subsequent contractile recovery. The research team aims to investigate the role of mtDAMPs in inflammatory responses and recovery of contractile function in cardiac grafts.
Researchers mapped opioid overdose death locations in Flint, Mich., finding three clusters with high concentrations in poorer neighborhoods. Only a small percentage of available treatment centers were located in these areas, highlighting the need for targeted resource allocation.
A study found that home-visiting by trained community workers during and after pregnancy can improve mother-child interactions. Mothers who received home visits displayed more maternal sensitivity, had harmonious interactions with their children, and had happier children at three years post-birth.
A study found a consistent association between state Prescription Drug Monitoring program adoption and death rates from heroin poisoning. States with Proactive PDMPs reported a 6% reduction in heroin poisoning mortality by the third year.
A new Stanford-led study provides a framework for environmental education programs to maximize impact. The research highlights four key facets: focusing on locally relevant issues, collaborating with experts, incorporating action-oriented learning strategies, and measuring outcomes. By implementing these principles, citizens can make m...
Research studies reveal that planktonic species diversity and functions change significantly according to latitude, with a peak around the equator and a decline towards the poles. These findings have strong ecological, environmental, and economic implications for ocean health and sustainability.
A new experimental approach captures how soil ecosystems respond to multiple drivers, revealing shifts in soil properties and microbial communities. The study's results could help identify dangerous factor combinations and tipping points for soil ecosystems in the future.
A novel method uses subcellular fractionation to quantify unconjugated AONs in nuclei, showing proportional relationship with target gene knockdown. Researchers report their results in Nucleic Acid Therapeutics, highlighting the importance of accurately quantifying oligonucleotides in therapeutic applications.
A new study by George Washington University's Amanda J. Visek found that girls and boys alike rank trying their best and working hard as key to having fun in youth sports, while winning is ranked 40th in importance. The study also uncovered small yet intriguing differences in fun priorities depending on age or gender.
Researchers discovered that Crohn's disease-associated bacteria can switch between replicating and non-growing states within macrophages to tolerate antibiotics. This stress response allows a reservoir of antibiotic-tolerant bacteria to survive in the host and cause long-term inflammation and irritation.
Researchers at Worcester Polytechnic Institute have created a wearable baby oxygen monitor that measures blood oxygen levels wirelessly and accurately. The device has the potential to improve healthcare outcomes for sick infants and adults with respiratory conditions.
Researchers discovered that cells with extra chromosome 21 in DS mice activated a biological circuit that detects stress and tamps down protein production, leading to cognitive impairments. By targeting this stress response, scientists were able to reverse learning and memory deficits in the mouse model.