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Healthy vascular fat during menopause may stave off dementia later in life

Researchers found that women with higher-quality cardiovascular fat during midlife had stronger long-term memory and lower inflammation, while those with lower-quality fat had worsening working memory. The study suggests that taking care of heart health during menopause may protect brain health and reduce dementia risk.

SourceUniversity of Pittsburgh·JournalAlzheimer s & Dementia·TypeObservational study·DateJun 5, 2023

Discovery of neurons that recognize others

Researchers at the Institute for Basic Science have identified specific neurons in the hippocampus that allow us to recognize individual social counterparts and update their value through interactions. The dorsal CA1 region plays a crucial role in this process, enabling long-term memories of individuals to be formed.

SourceInstitute for Basic Science·JournalNature Communications·TypeExperimental study·DateJun 1, 2023

Association between heart attack and cognition

A recent study of 30,465 adults without a history of heart attack or dementia found that those who experienced an MI had a faster rate of decline in global cognition, memory, and executive function compared to those without an MI. The study suggests that preventing heart attacks may be crucial for maintaining long-term brain health.

SourceJAMA Network·JournalJAMA Neurology·DateMay 30, 2023

Exposure to World Trade Center dust exacerbates cognitive impairment in an animal model of Alzheimer’s

Researchers found that mice exposed to WTCPM dust exhibit impaired spatial recognition and memory, as well as changes in genes related to immune-inflammatory responses. The study suggests a peripheral-brain immune inflammatory 'cross-talking' mechanism that may increase cognitive decline risk.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalJournal of Alzheimer’s Disease·TypeRandomized controlled/clinical trial·DateJan 17, 2023

Long-term memory in temperature series: the “forgetfulness” of state-of-the-art climate models in equatorial and coastal regions

Researchers found significant biases in climate models' simulation of long-term memory in temperature series, especially in equatorial and coastal regions. This may be due to imperfectly simulated coupled processes between oceans and atmosphere, leading to uncertainty in regional climate change predictions.

SourceInstitute of Atmospheric Physics, Chinese Academy of Sciences·JournalAtmospheric and Oceanic Science Letters·DateNov 9, 2022

During sleep, one brain region teaches another, converting novel data into enduring memories

Researchers used a neural network model to study how brain regions interact during sleep. They found that the hippocampus and neocortex work together to convert fleeting information into long-term memory. The findings suggest that alternating between REM and slow-wave sleep stages is crucial for strong memory formation.

SourceUniversity of Pennsylvania·JournalProceedings of the National Academy of Sciences·DateOct 24, 2022

How the smell of food can enable “time travel”

Researchers at Lancaster University found that 3D printed flavor-based cues can stimulate rich sensory accounts and strong emotional connections in older adults, recalling memories from their youth. This technology has potential applications for dementia care, allowing individuals to relive cherished moments through the power of smell.

SourceLancaster University·JournalHuman-Computer Interaction·TypeExperimental study·DateOct 5, 2022

Long-term memories a matter of order—not just repetition

A study by neuroscientists at New York University reveals that the brain's machinery interacts in nuanced ways to form long-term memories. The researchers found that neurons can sense not only repetition but also the order of repeated experiences, allowing them to discriminate between different patterns and build memories.

SourceNew York University·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateSep 26, 2022

Physical consequences improve motor learning

Research published in eNeuro found that physical consequences, such as slipping, can improve motor learning by refining movement responses to mistakes. Participants who experienced a slip improved their ability to adjust steps to new situations, demonstrating better generalization of learned skills.

SourceSociety for Neuroscience·JournaleNeuro·TypeExperimental study·DateMay 23, 2022

How can a protein help us remember?

Researchers have discovered the Apterous protein's crucial role in retaining memories through its interaction with the Chi cofactor and regulation of neurotransmitters. In fruit flies, Ap plays a double role in long-term memory consolidation, highlighting potential new treatment approaches for memory-related disorders.

SourceTokyo Metropolitan University·JournalPLOS Biology·DateDec 11, 2021

Prions may channel RNA’s messages

Researchers at Rice University have discovered a new mechanism by which prions can regulate protein synthesis in cells. The model proposes that prion aggregates and their monomers play a role in channeling RNA messages into new proteins, forming organized protein synthesis factories. This discovery has implications for our understandin...

SourceRice University·JournalProceedings of the National Academy of Sciences·TypeComputational simulation/modeling·DateNov 15, 2021

How neurons form long-term memories

Neuroscientists at Harvard Medical School have identified a critical gene, Fos, that allows neurons to rewire inputs from other neurons, enabling networks of disparate neurons to coordinate activity. This mechanism is thought to be essential for memory consolidation and recall.

SourceHarvard Medical School·JournalNature·DateDec 9, 2020

Puzzled otters learn from each other

Researchers observed Asian short-clawed otters solving food puzzles twice, several months apart, with the otters solving it 69% faster on average. This suggests a capacity for long-term memory and provides evidence of 'social learning,' where one otter's solution is quickly adopted by its closest friends.

SourceUniversity of Exeter·JournalRoyal Society Open Science·DateNov 10, 2020

New electronic skin can react to pain like human skin

Researchers at RMIT University have developed electronic artificial skin that senses pain instantly, mimicking the body's near-instant feedback response. The prototype device combines three technologies to deliver key features of the skin's sensing capability in electronic form.

SourceRMIT University·JournalAdvanced Intelligent Systems·DateSep 1, 2020

Memory boost with just one look

Researchers at HRL Laboratories found that targeted transcranial electrical stimulation during slow-wave sleep can improve metamemories of specific episodes by nearly 20% after just one viewing. This non-invasive approach may benefit patients with learning and memory deficits, as well as those with PTSD.

SourceHRL Laboratories·JournalFrontiers in Neuroscience·DateJan 14, 2020

Using light to learn

Research in fruit flies found that environmental light exposure activates light-sensitive neurons, triggering the production of memory maintenance proteins. This study suggests that long-term memories require active maintenance through natural lighting conditions.