Articles tagged with Long Term Memory
Scientists at the University of Florida have discovered that long-term memories are formed through experience-dependent changes in protein sets, which undergo reorganization to encode the brain's circuitry. This finding provides insight into the brain's plasticity and has potential implications for understanding neurological disorders.
Research found that experiencing three or more concussions is linked with worsened brain function in later life. Participants who reported multiple concussions showed significant cognitive decline, particularly in attention and complex task completion.
A study found that people can recall the location of over 100 objects on a grid with high accuracy, even after removing all images. Additionally, participants localized 60-80% of old items to within +/-10% of their correct time.
Researchers found that mice exposed to WTCPM dust exhibit impaired spatial recognition and memory, as well as changes in genes related to immune-inflammatory responses. The study suggests a peripheral-brain immune inflammatory 'cross-talking' mechanism that may increase cognitive decline risk.
Researchers found that remote fear memories are permanently stored in connections between memory neurons in the prefrontal cortex. The study suggests that a dysregulation of fear memory consolidation can lead to chronic maladaptive fear in PTSD, affecting about 6% of the population.
A team led by UMass Amherst scientist Margaret Stratton is studying the calcium-sensitive protein CaMKII to understand long-term memory and its potential therapeutic applications. The research has far-reaching implications for treating neurologic diseases, cardiac dysfunction, and infertility.
Researchers at MIT have discovered that the adult brain contains millions of silent synapses, which may explain how the brain forms new memories without modifying existing connections. These inactive connections can be recruited to help form new memories when important new information is presented.
Researchers found significant biases in climate models' simulation of long-term memory in temperature series, especially in equatorial and coastal regions. This may be due to imperfectly simulated coupled processes between oceans and atmosphere, leading to uncertainty in regional climate change predictions.
Researchers created a detailed map of the hippocampus's connections to the rest of the brain, finding fewer links with frontal lobes but more with visual networks. This discovery may change how we think about human memory and cognition, potentially shedding light on why some primates excel at certain memory tasks.
A new theory by UMass Amherst sleep scientist Rebecca Spencer suggests that young children's brain development, not age, determines when and why they stop napping. The hippocampus, a memory area of the brain, plays a critical role in nap transitions.
Researchers used a neural network model to study how brain regions interact during sleep. They found that the hippocampus and neocortex work together to convert fleeting information into long-term memory. The findings suggest that alternating between REM and slow-wave sleep stages is crucial for strong memory formation.
Researchers at Lancaster University found that 3D printed flavor-based cues can stimulate rich sensory accounts and strong emotional connections in older adults, recalling memories from their youth. This technology has potential applications for dementia care, allowing individuals to relive cherished moments through the power of smell.
A study by neuroscientists at New York University reveals that the brain's machinery interacts in nuanced ways to form long-term memories. The researchers found that neurons can sense not only repetition but also the order of repeated experiences, allowing them to discriminate between different patterns and build memories.
Scientists found that adolescent rats consuming low-calorie sweeteners like saccharin and stevia exhibited long-term impairments in memory. The researchers used real-life conditions and multiple low-calorie sweeteners to determine the effects on brain function and reward-motivated behavior.
Research by Tohoku University scientists found that contextual fear conditioning alters genes associated with the synapse in microglia, indicating a new mechanism linking microglia and neuronal activity related to fear conditioning. This non-immune communication may play a key role in fear memory consolidation and extinction.
A new Canadian study has found that older people with insomnia are at greater risk of developing memory decline and long-term cognitive impairment such as dementia. Insomnia was specifically related to worse memory performance compared to those with some insomnia symptoms alone or no sleep problems.
Researchers found that frog-eating bats could recognize ringtones indicating a food reward up to four years later. The bats learned to associate specific tones with rewards and were able to recall these associations even after long periods of time.
Researchers found that frog-eating bats trained to associate a phone ringtone with a tasty treat could remember what they learned for up to four years in the wild. The study, led by May Dixon at Ohio State University, used 49 bats and introduced three other ringtones without food rewards.
Research published in eNeuro found that physical consequences, such as slipping, can improve motor learning by refining movement responses to mistakes. Participants who experienced a slip improved their ability to adjust steps to new situations, demonstrating better generalization of learned skills.
Researchers at the University of Iowa have identified a fundamental biochemical mechanism underlying memory storage, which is impaired in Alzheimer's disease models. The study reveals that restoring this protein folding mechanism reverses memory impairment in mouse models.
Researchers have discovered the Apterous protein's crucial role in retaining memories through its interaction with the Chi cofactor and regulation of neurotransmitters. In fruit flies, Ap plays a double role in long-term memory consolidation, highlighting potential new treatment approaches for memory-related disorders.
Researchers at Rice University have discovered a new mechanism by which prions can regulate protein synthesis in cells. The model proposes that prion aggregates and their monomers play a role in channeling RNA messages into new proteins, forming organized protein synthesis factories. This discovery has implications for our understandin...
Researchers found that a balance between dopamine D2 receptors and RGS is crucial for normal long-term memory formation. An imbalance in these molecules is thought to contribute to the development of schizophrenia and dystonia.
A new study reveals that some gifted dogs can learn up to 12 new toy names in just one week and remember them for at least two months. The researchers tested these talented dogs as part of the Genius Dog Challenge, a series of live broadcasted experiments.
Researchers discovered that a brain area traditionally thought to specialize in old habits also plays a role in learning new actions. The study found that the dorsolateral striatum is involved in consolidating action learning immediately after the new action has been learned.
Researchers have identified a population of neurons in the brain's temporal pole region that collectively remembers familiar faces, including those of loved ones. This discovery sheds new light on how our brains process and remember faces, with potential implications for understanding conditions like prosopagnosia.
A new Northwestern University study reveals that the hippocampus is not just essential for long-term memory but also supports short-term memory and guides decision-making. The findings suggest that the hippocampus uses short-term memory to inform where we look, priming our visual system to learn and reevaluate our environment on the fly.
A study from King's College London found that intermittent fasting increased Klotho gene expression and promoted adult hippocampal neurogenesis in mice, leading to improved long-term memory retention. The researchers hope to replicate the study with human participants to further explore the effects of IF.
Researchers have identified a specific brain region that facilitates recovery from long-term traumatic memories, known as the nucleus reuniens. By enhancing its activity, they found that long-lasting traumatic memories can be facilitated towards safety.
A shared set of brain regions play an important role in controlling the successful retrieval of weak memories, according to a new University of York study. The research may have implications for treating memory disorders like dementia and developing more advanced artificial intelligence systems.
Early childhood memory abilities predict the strength of future brain connections, while the strength of early brain connections predicts future memory acuity. This study highlights the complex relationship between brain function and ability during development.
A new study by Tokyo Medical and Dental University researchers suggests that melatonin and its metabolite AMK promote long-term memories in mice and shield them from cognitive decline. In the study, young and aging mice were able to form and recall memories after receiving doses of melatonin and AMK.
Neuroscientists at Harvard Medical School have identified a critical gene, Fos, that allows neurons to rewire inputs from other neurons, enabling networks of disparate neurons to coordinate activity. This mechanism is thought to be essential for memory consolidation and recall.
A three-year grant has been awarded to Montclair State University and Kessler Foundation researchers to explore treatments for long-term memory impairments in individuals with traumatic brain injury. The study aims to develop innovative treatment strategies directed at process-specific remediation of cognitive and neural mechanisms und...
Scientists at the University of Basel have identified a key protein regulating long-term memory, found to decline with age. By studying roundworms, they discovered that a molecule called MPS-2 plays a central role in intact long-term memory and is also involved in age-related memory loss.
Researchers observed Asian short-clawed otters solving food puzzles twice, several months apart, with the otters solving it 69% faster on average. This suggests a capacity for long-term memory and provides evidence of 'social learning,' where one otter's solution is quickly adopted by its closest friends.
Researchers have identified a new key player in long-term memory formation, the connection between mossy cells and granule cells in the hippocampus. This discovery sheds light on how new environments are processed and stored in the brain.
Researchers at RMIT University have developed electronic artificial skin that senses pain instantly, mimicking the body's near-instant feedback response. The prototype device combines three technologies to deliver key features of the skin's sensing capability in electronic form.
Scientists at Tokyo Metropolitan University have discovered that traumatic memories can be erased in Drosophila flies when exposed to environmental light. The team identified the molecular mechanism responsible for this effect, which involves the regulation of proteins in the brain.
Research by University of Kent found that moderate intensity exercise, such as brisk walking or cycling, significantly benefits long-term memory performance. The study suggests that moderate exercise is a more effective approach than highly strenuous exercise for improving memory.
A new study found that testing enhances both memory and the ability to make inferences about subject matter. The researchers tested participants with either rote restudy or testing, and found that testing improved long-term memory and inference over a period of 25 days.
A study in mice reveals that new nerve insulation, myelin, plays a critical role in laying down long-lasting emotional memories. Increased myelin formation is necessary for the consolidation and maintenance of fear memories, which could lead to new treatments for post-traumatic stress disorder.
Researchers at HRL Laboratories found that targeted transcranial electrical stimulation during slow-wave sleep can improve metamemories of specific episodes by nearly 20% after just one viewing. This non-invasive approach may benefit patients with learning and memory deficits, as well as those with PTSD.
Research in fruit flies found that environmental light exposure activates light-sensitive neurons, triggering the production of memory maintenance proteins. This study suggests that long-term memories require active maintenance through natural lighting conditions.
A study from Scripps Research reveals that memories are stored in two forms: intermediate-term memory and protein-synthesis dependent long-term memory. Silencing specific genes, Ras and Raf, enhances intermediate-term memories while eliminating long-term memory performance.
A team of neuroscientists suggests that the sensation of a 'food coma' after eating may be linked to the formation of long-term memories. In a study on brain activity in Aplysia californica, sea slugs, researchers found that insulin-like molecules play a crucial role in both metabolic and neurotropic functions.
Researchers aim to develop treatments for behavioral symptoms of chronic stress and depression by understanding and controlling memory. Beier's project explores neuronal plasticity and synaptic protein interactions to engineer molecular reagents for selective modulation of memories.
A study published in Nature Communications elucidated transcription factors and enzymes controlling brain processes through DNA methylation, shedding light on long-term memory storage. This research has significant implications for understanding Alzheimer's disease and potentially enhancing learning.
Scientists have detailed the structure of calcium-calmodulin-dependent kinase II (CaMKII), a key protein involved in encoding memories. The study reveals how CaMKII binds to actin filaments, forming rigid bundles that support dendritic spines and enable cognitive functions.
Drosophila melanogaster forms a stable long-term memory for its body size and reach after hatching from the pupal case. The insects learn to estimate distance across gaps by linking visual information with their body size, retaining this knowledge for life.
A recent study in mouse neurons reveals how the protein CPEB3 primes neurons to store long-term memories. P bodies, specialized isolation chambers within neurons, contain dormant CPEB3 and transfer it to synapses, where it strengthens connections and stabilizes memories.
A Johns Hopkins University study reveals that older adults with weaker brain connections experience interference, making it harder to access long-term memories. The research highlights the importance of suppressing irrelevant information for optimal cognitive function.
Researchers found that snails can store and recall two unrelated memories but struggle with similar ones. They discovered an overlapping mechanism causing proactive interference, leading to the loss of older memories. Practicing interweaving and learning different topics can help retain more information.
A breakthrough study reveals the anterior cingulate cortex plays a crucial role in synchronizing brain waves to retrieve long-term memories after two weeks. This discovery could lead to new treatments for Alzheimer's disease and other forms of dementia by understanding how our brains process and access older memories.
Researchers at U of T discovered the human hippocampus is sensitive to time information on short timescales, helping bind together information about time when forming long-term memories. The study builds on a previous rodent study that found 'time cells' in the hippocampus.
Researchers found that blue whales' migration patterns are driven by the timing of spring phytoplankton blooms and their ability to remember stable foraging sites. This allows them to optimize food tracking and forage in areas with higher long-term productivity.
Researchers at the University of Tokyo found that histamine improved people's long-term memory test scores, especially for those with poor memories. The study showed mice could recognize toys they'd seen as long as 28 days ago after receiving a medication that increases histamine in the brain.
Researchers found that engram neurons, responsible for long-term memory, are formed through a transcriptional cycling process involving MAPK and CREB. This discovery has implications for understanding the mechanisms of learning and improving memory, as well as developing treatments for memory impairment.
A study published in Psychological Science found that exploring objects through touch generates durable memories, even when participants don't intend to memorize details. Participants recalled objects with high accuracy after just one week, challenging existing cognitive and neural models of memory storage.
Research on GHB users found associations with negative emotions identification, altered brain processes during verbal long-term memory and working memory, lower IQ, and increased stress and anxiety. Brain scans revealed changes in brain activity and connectivity between memory-related pathways.