Articles tagged with Long Term Memory
A study published in Cell reveals that lactate from astrocytes plays a crucial role in forming and maintaining long-term memories. The findings have significant implications for treating Alzheimer's disease, dementia, and diabetes.
Researchers at the NIH have discovered that increasing activity of brain enzyme PKMzeta enhances long-term memories in rats, while decreasing it erases them. This finding has significant implications for treating debilitating emotional memories and enhancing faltering memories in disorders of aging.
Astrocytes are essential for making long-term memories, and their dysfunction can lead to amnesia. Long-term memory formation depends on the delivery of lactate from astrocytes into neurons.
Mount Sinai researchers have identified insulin-like growth factor II (IGF-II) as a potential therapeutic target for enhancing long-term memory and preventing its loss. IGF-II, a gene expressed during brain development that declines with aging, was found to improve long-term memory in rats by promoting stable LTP.
Researchers at MIT's Picower Institute of Learning and Memory discovered that relatively minor details are sometimes linked to long-term memories. They found that irrelevant information that follows a relevant event is more likely to be integrated into long-term memory, and that this can occur within an hour and a half after the event.
A University of Iowa study reveals that young men vary in their ability to remember sexual cues, with good-looking women being more easily recalled. Men with a history of serious relationships perform better, while those with higher aggression scores do worse.
A new study in Applied Cognitive Psychology found that college-aged men can accurately remember a woman's initial sexual interest based on visual cues. The study suggests that tracking and remembering a partner's emotions may play a role in the initiation and maintenance of serious romantic relationships.
Researchers from UCI and Scripps discovered that myosin II proteins play a critical role in synaptic plasticity and learning, suggesting new therapeutic targets for memory-related disorders. This finding adds an unexpected dimension to the story of how memories are encoded.
Research at Princeton University found that caloric restriction impairs long-term memory in early adulthood but does not further decline it with age. In contrast, reducing insulin signaling improves learning ability and maintains it better with age. The study has implications for treating cognitive decline associated with aging.
Researchers found that longevity treatments have different impacts on learning and memory in C. elegans, a nematode species. Dietary restriction improved early adult memory but declined with age, while reduced Insulin/IGF-1 signaling enhanced memory performance but failed to preserve it with age.
A new study found that smoking, but not past alcohol abuse, may impair mental function in women. Women who had ever been addicted to smoking scored lower on cognitive tests than their nonsmoking counterparts.
Researchers have discovered that the brain's hippocampus replay process is a complex cognitive function that helps animals learn and maintain their internal representation of the world. This process involves replaying experiences, even those previously unencountered, to create connections within the cognitive map.
A new study published in Journal of Consumer Research reveals that scent significantly enhances recall of product information, with scented products remembered better than unscented ones. The researchers found that product scent is more effective at enhancing memory for product-related information than ambient scent.
Researchers at Karolinska Institutet have discovered a mechanism that controls the brain's ability to create lasting memories. The study found that signalling via the nogo receptor 1 plays a key part in this process, enabling the conversion of short-term memories into long-term ones.
Researchers discovered two distinct short-term memory networks: one independent of the hippocampus and another dependent on it, which are impaired alongside long-term memory. Patients with impaired long-term memory have a significant short-term memory burden.
Neuroscientists have identified a protein called SHP-2 phosphatase that controls the spacing effect, which enhances long-term memory by adjusting rest intervals. The study found that manipulating SHP-2 phosphatase activity can reverse memory deficits in mutants with Noonan's syndrome.
Reijmers is investigating the proteins involved in long-term memory storage, with potential applications in treating diseases like Alzheimer's. His research aims to understand the mechanisms of memory and apply them to various fields, including addiction, epilepsy, and spinal cord regeneration.
A recent CSHL study has found that fruit flies require the same gene, rutabaga, for short- and long-term memories but in different circuits. Short-term memory is initiated in the gamma lobe, while long-term memory is established in the alpha-beta lobe.
Researchers have discovered that actin reorganization in two stages is controlled by different pathways, making it easy to encode new memories but hard to hold onto them. The Rho-ROCK pathway initiates cytoskeletal changes, while the Rac-PAK pathway solidifies them, leading to heightened synapse sensitivity and memory persistence.
A study by McGill University researchers has captured an image of a mechanism underlying long-term memory formation. New proteins are made locally at the synapse, increasing synaptic strength and reinforcing memories.
A study on rats reveals that neural replay of past experiences occurs both during and after wakefulness, forming long-term memories more accurately. The hippocampus replays events in peppered bursts, often involving different settings, suggesting elements of past experience are constantly reactivated.
Researchers have discovered that calcium modulation affects long-term memory specifically while leaving learning and short-term memory intact. The study found that increased calcium levels during learning led to stronger responses to olfactory stimuli associated with food, indicating improved memory performance.
Researchers at UT Southwestern Medical Center discovered two biochemical signals promoting the development of memory cells in immune cells. These signals, interferon alpha and IL-12, play distinct roles in driving immediate and long-term immunity.
A team led by Li-Huei Tsai has pinpointed the exact gene responsible for reversing Alzheimer's-like symptoms in mice. The researchers found that drugs targeting HDAC2 reverse cognitive function and boost memory formation, offering new hope for treating neurodegenerative diseases.
Researchers found that consuming fat-rich foods enhances memory consolidation, triggering long-term memories of the activity. OEA, a compound produced in the small intestine, plays a key role in this process.
A team of Dutch researchers successfully reduced the fear response in human volunteers using beta-blocker propranolol. The treatment weakened fear memories, allowing them to be erased from long-term memory. This breakthrough has implications for treating anxiety disorders and offers a new approach to intervention.
A new study by Nicole Votolato Montgomery and H. Rao Unnava found that consumers tend to favor vacations with improved outcomes over those with worsened outcomes when evaluated immediately, but reverse preferences emerge after a delay.
SUNY Downstate researchers discovered that the PKMzeta molecule stores complex memories while leaving other brain functions intact. This finding suggests that targeting specific debilitating memories with PKMzeta erasure could be effective in treating conditions like depression, anxiety, and addictions.
A Canadian scientist has made a significant breakthrough in treating intellectual disabilities by manipulating the genes of fruit flies. The research found that disrupting a specific gene called FMR1 leads to long-term memory loss, and that a class of drugs can help restore memories.
A Baylor College of Medicine neuroscientist has identified a single molecule that can affect memory, with findings showing that reducing activity of a key protein increases the expression of genes and proteins needed for long-lasting memories. The study also reveals that short exposure to experiences creates long-term memories.
Dr. Mauro Costa-Mattioli has discovered a type of molecular switch in mice that determines whether a long-term memory is formed from an experience, improving spatial memory and synaptic connections. His research holds hope for developing new therapies for age-related memory loss and Alzheimer's Disease.
A study by Duke University Medical Center reveals that strong emotions and scents create lasting memories even when we're asleep. The researchers found that noradrenaline and odor cues are essential for memory formation, leading to changes in behavior upon waking.
A University of Haifa research team has identified a protein, PSD-95, crucial for stabilizing long-term memories. The study found that inducing PSD-95 production during memory creation is necessary for memory retention, while its absence does not affect existing memories.
Researchers have discovered that the blood-boosting effects of erythropoietin are not related to its impact on cognition. Instead, EPO directly influences neurons in the brain, improving memory and cognitive function. The findings may lead to new treatments for neurodegenerative diseases.
Researchers have discovered a complex process in the brain that regulates synaptic connections during learning and memory, involving a specific presynaptic protein regulated by postsynaptic calcium. This understanding may lead to interventions for human brain disorders and age-related memory loss.
Octopus brains utilize activity-dependent long-term synaptic potentiation (LTP) to store and recall memories, with findings suggesting a segregation of short and long-term memory systems. This process is comparable to that discovered in vertebrate brains, yet operates differently due to the octopus's unique brain anatomy.
Researchers found that honeybees use their right and left antennae to store different types of memories. Short-term memory is linked to the right antenna, while long-term learning relies on the left antenna. This lateralization may aid bees in learning new odours without interference from existing memories.
Nautilus pompilus demonstrated short-term memory lasting up to an hour before fading away, but remembering it again after 6 hours. The living fossil's memory was comparable to that of modern cephalopods, challenging the assumption that complex brains are necessary for memory.
Researchers found that phytochemical-rich foods like blueberries improve spatial working memory tasks within three weeks. The enhancement is attributed to flavonoids, which stimulate neuronal regeneration and improve cellular communications.
Researchers find working memory retains only a few high-resolution images for a short period, similar to a high-resolution camera. This limited capacity is linked to intelligence and fluid thinking abilities.
A study at NYU and Weizmann Institute of Science identified brain activation patterns linked to long-term memories by simulating everyday experiences. The researchers found activity in new areas, including the temporal pole, STG, mPFC, and TPJ, which have been implicated in social cognition.
Researchers found that PKMzeta is necessary for storing long-term memories in the neocortex, a part of the brain responsible for higher-level cognitive functions. Persistent phosphorylation by PKMzeta is crucial for storing these memories.
Scientists found that long-term memories require a miniature molecular machine to maintain, which must be constantly active. Jamming this 'machine' can briefly erase memories, suggesting potential future treatments for memory problems.
Researchers challenge long-held assumption that new protein synthesis is necessary for recording memories in long-term storage. Brain chemistry changes caused by protein synthesis inhibitors can disrupt memory formation instead.
Researchers at Johns Hopkins Medicine have discovered a new biochemical mechanism for memory storage, involving persistent changes in slow nerve currents. The discovery may also link memory and addiction, with potential implications for treating conditions such as epilepsy and diseases of memory.
Brandeis University researchers have identified CaMKII as a key molecule in memory storage, allowing them to induce and biochemically erase memory in rat hippocampus slices. This discovery holds promise for treating Alzheimer's and epilepsy by weakening overly strengthened synapses.
Researchers found that enriched environments improved learning and memory in mice with neurodegeneration due to p25 activation. The animals showed significant gains on memory tests and recovered long-term memories weeks after training. However, no evidence of new neuron growth was observed.
Researchers found that sleep enforces the temporal sequence in memories by replaying experiences in a forward direction. This process enhances word recall when students were asked to reproduce learned words in the correct order.
A gene mutation in mice results in enhanced long-term memory, pointing to a potential target for developing a drug to treat memory loss. The mutation affects the phosphorylation of a protein involved in regulating gene expression, leading to improved performance in memory tests.
A team of researchers from Baylor College of Medicine has found a key component in the formation of long-term memory in fruit flies. The study showed that increased calcium influx into mushroom body neurons parallels the creation of new synapses associated with long-term memory, and can be blocked by specific laboratory techniques.
Researchers challenge long-held theory of memory storage by discovering the neocortex drives dialogue between old and new brain regions during deep sleep. The study uses single-cell recordings to show synchronized communication, suggesting a reversal in traditional understanding of memory consolidation.
Researchers at the Salk Institute found that fisetin stimulates signaling pathways that enhance long-term memory in healthy mice. Fisetin was shown to induce differentiation of neural cells and activate a signaling pathway involved in memory formation, called long-term potentiation.
Researchers have found that proteins essential for brain growth during development are equally important for forming long-term memories. Growth factors like BDNF play a critical role in retaining long-term memory by binding to specific receptors in the brain, and their absence can block this process.
Scientists at SUNY Downstate Medical Center discovered a molecular mechanism maintaining memories in the brain by inhibiting a specific enzyme, protein kinase M zeta. This finding may have applications in treating chronic pain and memory loss conditions such as post-traumatic stress disorder.
A new study offers insights into the role of the hippocampus in forming and recalling memories, particularly for working memory. The researchers found that the hippocampus plays a crucial role in connecting related pieces of information, but not necessarily in long-term memory.
Researchers at University College London discovered that brain activity before an event is linked to memory recall. The study used EEG scans to show that preparing the brain for a task can enhance long-term memory, and that this preparation can be done by being 'in the right frame of mind' and staying alert between cues.
A team of scientists found that electric fish can store memories through the activation of ion channels called TRP channels, which remain active for a long time. This discovery could help researchers better understand memory formation and neural disorders like epilepsy in humans.
Activation of protein kinase A (PKA) solidifies fear memory in the brain, according to Yale researchers. The study found that selective PKA activation enhances reconsolidation and strengthens previously established fearful memories.
Researchers found a biochemical pathway, called RISC, that facilitates protein synthesis at synapses during learning, enabling long-term memory formation. By manipulating this pathway, scientists increased flies' memory and altered their behavioral responses to stimuli.
Researchers in Montreal have made a groundbreaking discovery about the genetic basis of memory. They found that the GCN2 protein inhibits long-term memory storage, preventing new information from being stored for extended periods.