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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Level-headed: Economics experiment finds taste for equality

A new study published in Nature found that participants in a game were willing to reduce their own earnings to increase another player's income, demonstrating a preference for economic equality. The results suggest that egalitarian motives underlie human cooperation and reciprocity.

Dairy, fruits and veggies may help smokers quit

A study found that dairy products, non-caffeinated beverages, and fruits/vegetables can worsen the taste of cigarettes. Researchers propose a 'Quit Smoking Diet' or alternative treatments to deter smoking.

Personalized diets may offer relief to advanced cancer patients

Researchers at the University of Alberta found that advanced cancer patients experience unique and persistent taste and smell abnormalities, leading to malnutrition and poor quality of life. A personalized diet tailored to an individual's needs may improve their quality of life.

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Molecules under the hammer

Dutch researcher Rajesh S. Pillai developed a new method to visualize the microstructure of food and lipid droplets in cells using short infrared laser pulses. This technique has high promise for research into fat storage and diseases related to disrupted lipid metabolism.

More than meets the tongue

A recent study by JoAndrea Hoegg and Joseph W. Alba found that the color of a drink can significantly affect how it tastes, with tint dominating taste perception over other attributes.

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Tastes great! Study shows brain's response to pleasing -- and changing -- tastes

Researchers tracked brain activity in rats while they tasted water, salt water, and sugar water, finding that a formerly disliked taste became pleasurable when the rats were deprived of salt. This study provides new insights into how the brain processes pleasure and has implications for understanding eating disorders and addiction.

Honey bee chemoreceptors found for smell and taste

Researchers found that honey bees have 170 odorant receptors, compared to 62 in fruit flies and 79 in mosquitoes. This allows them to detect pheromones, find food, and communicate with each other through subtle olfactory cues.

Black tea soothes away stress

A study by University College London researchers found that black tea consumption reduced cortisol levels and blood platelet activation after stressful events. The study, published in Psychopharmacology, suggests that drinking black tea may speed up recovery from daily stresses.

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Researchers examine why food tastes bad to chemotherapy recipients

A research team led by Virginia Tech professor Andrea Dietrich aims to identify the cause of metallic flavors in chemotherapy patients and develop preventive methods. The study will also explore the role of antioxidants and investigate the relationship between metal ions and health outcomes.

Bitter taste identifies poisons in foods

Bitter taste perception varies among individuals due to genetic differences, influencing the detection of toxins like glucosinolates in vegetables. This study establishes a link between bitter taste receptors and toxin detection, providing insights into evolutionary mechanisms.

Researchers identify the cells and receptor for sensing sour taste

Researchers identified the cells and receptor responsible for sour taste, a primary gateway in all mammals for detecting spoiled food sources. The PKD2L1 receptor is found in a subpopulation of taste receptor cells on the tongue that do not function for sweet, bitter, or umami taste.

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Scientists solve sour taste proteins

Researchers identified PKD1L3 and PKD2L1 proteins in human taste buds responsible for detecting sour tastes. The discovery could lead to developing ways to alter the perception of sour tastes, such as in children's medicines or health foods that currently taste sweet.

Dr. McCluskey receives top honor for young taste researchers

Dr. McCluskey receives the Ajinomoto Award for Young Investigators in Gustation for her work on taste bud regeneration and its relation to the immune system. She aims to understand how macrophages, a type of immune cell, affect neural function in injured nerves.

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New groundbreaking findings in taste, smell and chemical irritation

Researchers present new discoveries on topics ranging from molecular biology to clinical diagnosis and treatment of smell and taste disorders. Key findings include zebrafish exhibiting robust light responses, flavor and fragrance scientists working to uncover basic science behind sensory delights.

Sweet chemistry: Symposium explores sugar alternatives, science of taste

Researchers are developing new artificial sweeteners and non-calorie sweetness enhancers to reduce health risks associated with high sugar consumption. The ACS symposium highlights potential breakthroughs in treating taste disorders, identifying supertasters at risk of colon cancer, and creating safe natural sweeteners.

HortResearch science reveals the natural potential of apples

Researchers at HortResearch have completed public release of world's most extensive apple DNA sequences, unlocking secrets of taste, health and color. The release comprises over 50,000 apple gene sequences, enabling fruit breeders to create new varieties tailored to consumer tastes and industry demand.

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Living taste cells produced outside the body

Researchers have successfully created living taste cells in a lab culture, opening new avenues for understanding the sense of taste and potentially treating disorders. The breakthrough could lead to new insights into how basal cells turn into functional taste cells.

Taste gene may play role in smoking

A recent study published in Nicotine and Tobacco Research found a significant link between genetic variations in the PTC gene and smoking behavior. Smokers with reduced bitterness sensitivity were more likely to smoke for taste, while those with a specific less common genetic variant were 20% less likely to smoke.

Great (taste) expectations: Study shows brain anticipates taste, shifts gears

A team of University of Wisconsin-Madison scientists reports that the brain can be rewired in anticipation of sensory input to respond in prescribed ways. By manipulating expectancy, the brain code for tastes is activated less when a cue suggests a lesser taste, and the perception of the taste matches the prediction.

Think your friends know you pretty well? Think again

A study by Andrew D. Gershoff and Gita Johar found that people overestimate their closest friends' knowledge of their tastes and preferences, leading to less accurate recommendations. The researchers suggest that this overestimation is driven by a desire to maintain self-image and protect relationships.

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How taste response is hard-wired into the brain

The study reveals that specific cells in fly brains detect distinct tastes, with separate neurons responding to sweet and bitter substances. This discovery suggests a model of taste encoding in the brain where dedicated neural circuits dictate behavioral outputs.

A spoonful of sugar makes some kids feel good

Researchers found that sweet taste's analgesic efficacy is influenced by how much a child likes sweets and their weight status. In the study, sucrose preferences were determined for 198 children, with those who preferred higher levels of sweetness experiencing reduced pain when consuming sweet tastes.

Salty taste preference linked to birth weight

Research found that infant birth weight is inversely related to salty taste acceptance, suggesting a lasting influence on flavor and food preferences. The study's results could inform programs aimed at reducing salt intake, which is linked to high blood pressure.

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Nose odors and mouth odors: The brain distinguishes

Researchers found that brain responds differently to odors introduced through the nose versus the mouth, with distinct brain regions activated. The study suggests that olfactory referral illusion is robust and cognitively impenetrable, and may play a role in flavor perception.

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Bitter or sweet? The same taste bud can tell the difference

Researchers at Ohio State University found that neuropeptide Y (NPY) and cholecystokinin (CCK) peptides trigger different responses in taste bud cells, helping the brain distinguish between bitter and sweet tastes. The study's findings provide new insights into how our brains process taste information.

Good, bad and indifferent

A study published in Journal of Consumer Research reveals how consumers evaluate an experience by drawing connections between positive and negative events. The research suggests that people find comfort in ambivalence when a bad experience is compared immediately to a good one, providing valuable insights for marketing professionals.

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Brain center shows there is accounting for taste

Researchers found that brain center's neurons encoded learning associated with taste stimuli, revealing different circuitry for processing rewarding and aversive stimuli. The study supports the idea that individual NAc neurons play a role in aversion and Pavlovian learning.

Children's taste sensitivity and food choices influenced by taste gene

Researchers found that genetic variation in the TAS2R38 gene affects bitter taste sensitivity in children, influencing their food preferences. Children with a bitter-sensitive allele prefer sweeter tastes, while those with two bitter-insensitive alleles tend towards vegetable consumption.

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Dartmouth researcher mines Amazon.com to measure literary tastes

A Dartmouth researcher uses Amazon.com book ratings and reviews to study literary tastes, finding patterns in how readers react to different books. The analysis reveals predictable regularities in taste, including high grades for classics and books with large fan bases.

What colour is that sound?

Professor Daphne Maurer's research found that infants perceive sounds as colors and associate certain feelings with tastes. As individuals develop, these connections are often inhibited, leading people with synesthesia to experience the world differently.

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GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

Vegetable lovers should be viewed as different from fruit aficionados

A study by Brian Wansink found that vegetable enthusiasts eat more spicy foods, drink wine with dinner, and cook elaborate meals. Fruit lovers prefer sweets, are less adventurous in the kitchen, and eat desserts after dinner. Tailoring healthy eating recommendations to these groups can be more effective.

Coke versus Pepsi: It's all in the head

A recent study found that Coke preference is influenced by brand knowledge and activates specific brain regions, including the hippocampus. This discovery highlights the role of cultural messages in shaping taste perception and has important implications for understanding obesity and other health issues related to sugared colas.

Toward a better understanding of taste and smell impairments

A multidisciplinary team is investigating the impact of inflammation on taste and smell function, with potential therapeutic interventions for chemosensory dysfunction. The studies aim to improve diagnosis and treatment targeting for patients with conditions like chronic rhinosinusitis and radiation-induced taste loss.

One taste of growth protein and nerve cells want more

In a breakthrough study, Johns Hopkins scientists identified that nerve cells use target-derived cues and proteins like NGF to guide them to their final targets. The research sheds new light on the complex process of nerve growth and cell targeting during development.

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A fly's taste experience is much like our own

A study by UC Berkeley neuroscientists found that fruit flies have taste receptors similar to humans, with four types devoted to sweet and bitter flavors. The researchers mapped the taste receptor nerve cells into the brain, revealing a map both of location and type of taste.

Flies may taste bitter better, first map of insect 'tongue' reveals

Researchers at Duke University Medical Center found that flies have distinct combinations of bitter-sensitive nerve cells on their tongue, allowing them to discern among different bitter tastes. This unique ability might enable flies to select the best food item among multiple suboptimal choices.

The preference for sweetened foods may decline after exercise

A study found that exercise can reduce the preference for sweetened fluids in rats, with a temporary increase in perception of sweetness after consumption. The researchers suggest that this could lead to the development of foods and supplements that meet post-exercise nutritional needs.

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First flavors form a lasting impression

A study found that infants fed protein hydrolysate formula for seven months developed a taste preference for the formula, while those fed standard milk-based formula rejected it. Early flavor exposure influences long-term food choices.

Food tastes stronger when you're hungry

Research suggests that hunger increases sensitivity to sugar and salt, as the body tries to consume food. However, this effect does not apply to bitter tastes, which may be more related to detecting toxins.

On the tip

USC neuroscientist Emily Liman founds that calcium acts as a bridge for taste cells to send signals to the brain about what's been tasted. The study reveals new details on how the sense of taste works and could lead to the development of better artificial sweeteners or additives.

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Researchers define molecular basis of human 'sweet tooth'

Researchers have discovered that specific receptor molecules on the tongue trigger taste cells to transmit signals to the brain, governing sweet and umami tastes. The study's findings suggest individual variations in 'sweet tooth' responses may stem from subtle genetic differences in these receptors.

Processing with flavonoids can mean tastier, heart healthy food

A new study from Penn State finds that flavonoids at heart-healthy levels do not automatically increase bitterness but can promote good flavor development and palatability in some food products. The presence of flavonoids was shown to limit the generation of off-flavors in heated food, including ultrapasteurized milk.

U. Iowa study adds to understanding of salt-taste

Researchers at U. Iowa identified two ion channel genes that detect low salt concentrations in fruit flies, a model organism for studying human salt-sensing mechanisms. Disrupting these genes impaired the ability of young flies to detect low salt, highlighting their role in the detection of salt.

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