Johns Hopkins researchers have identified two genetic mutations that may cause or contribute to nearly half of all non-inherited cases of ALS. The mutations involve a glutamate transporter protein, EAAT2, which normally deactivates and recycles glutamate, leading to increased paralysis and death in two to five years.
The world's first Dynamic Voltage Restorer (DVR) has entered commercial service on Duke Power's system, correcting a severe voltage sag at Orian Rugs in South Carolina. The DVR uses advanced power electronics to rapidly inject energy onto the line and restore 100% voltage within 30 cycles.
Researchers found that naked mole-rats prefer to recruit family members to new food sources rather than eating them themselves. The rodents use a unique recruitment chirp and chemical trails to guide their kin to the food, even in pitch-black tunnels.
SRI International will operate a 150-foot parabolic reflector antenna to test UHF communication signals from the Mars Global Surveyor spacecraft. The team will analyze received signals in real-time and send simulated signals to check the UHF link for future Mars missions.
Researchers found two production-boosting genes, YLD1 and YLD2, in wild rice O. rufipogon that improved crop yields by 15-17% when combined with domesticated varieties. The study aims to reverse genetic erosion and selectively enrich the genetic base of crop plants.
The discovery of EUV emissions in the Coma cluster suggests a large cloud of cooler matter, totaling up to 10 trillion of our Suns, which could help clear up a major problem with these galactic groupings. The findings also hint at the presence of normal baryonic matter instead of dark matter or exotic particles.
Scientists at Yerkes Primate Research Center of Emory University found that cocaine significantly alters the activity of nearly 20 genes in the brain, many of which have never been identified. The changes occur during transcription and may have serious long-lasting consequences for addiction.
Scientists have identified a major gene, HPC-1, that predisposes men to prostate cancer, located on chromosome 1. The gene is believed to contribute to at least a third of familial prostate cancer cases.
A study in rats found that natural estrogen levels provide significant neuroprotection against stroke damage, sparing up to three times more brain tissue than male counterparts. Researchers are now investigating the optimal dose of estrogen for this effect and its potential as a brain-protective therapy.
Researchers have exposed the precise interactions between antibiotics and bacterial ribosomes, revealing a 'lock-and-key' system that sheds light on antibiotic effectiveness and resistance. The study highlights the importance of targeting RNA in cells and provides potential strategies for designing new, less toxic drugs.