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Science News for April 6, 1998


Structure Of Tumor Necrosis Factor-Alpha-Converting Enzyme Solved - Milestone Toward Rational Drug Design For Rheumatoid Arthritis And Endotoxic Shock

Researchers solved the crystal structure of human tumor necrosis factor-alpha-converting enzyme (TACE), revealing its unique features and providing insights into its role in inflammatory diseases. The study's findings have significant implications for developing targeted therapies for rheumatoid arthritis and septic shock.

SourceMax-Planck-Gesellschaft·JournalProceedings of the National Academy of Sciences·DateApr 6, 1998