Scientists from Ligand Pharmaceuticals Incorporated have discovered two novel non-steroidal progestin compounds, (S)-LG120746 and (S)-LG120747, that selectively stimulate tissues within the body. These compounds demonstrate a protective activity in the uterus without concomitant stimulation of breast-cell growth.
A University of North Carolina at Chapel Hill study found that St. John's Wort can cut alcohol consumption in laboratory animals by up to 50 percent. The herb's active ingredient, hypericin, may prove effective in the fight against alcoholism without causing side effects.
Researchers at University of Chicago and Johns Hopkins Medical Institutions identify genetic regions on chromosomes 1p, 3q, and 4q that appear to contain genes triggering the onset of inflammatory bowel disease. The study confirms the role of previously localized gene IBD1 in concert with another disease gene on chromosome 1.
A new computer program called POMPOUS has been developed to predict genetic markers with high accuracy, accelerating the discovery of gene function and reducing costs. The program has identified over 13,000 markers on the human genome, enabling researchers to analyze and identify genes more efficiently.
A Cornell University study reveals that 6.4 million homes have modifications to accommodate elderly residents' physical limitations. The most common types of modifications include bathroom grab bars and wheelchair ramps, with 60% of homes with someone over 90 modified for mobility.
A study found that modafinil significantly improved the quality of life for patients with narcolepsy, reducing daytime sleepiness and increasing productivity. The medication provided sustained benefits over an extended period without debilitating side effects.
At the Institute of Food Technologists' annual meeting, Cornell's 'Wrapidos' took top honors for its leak-proof and moisture barrier design. The snack, consisting of shaped pita pockets wrapped around three sides with an open side for stuffing, was inspired by a mother-daughter duo's request for a mess-free snacking solution.
The largest generation of adolescents is at risk of premarital pregnancy, STDs, and adverse health effects. Key findings include increased time between first intercourse and marriage, low contraceptive use among teens, and the influence of peers and partners on adolescent sexuality.
Researchers warn that antidepressants can lead to dental cavities and oral infections by reducing saliva production. Saliva is essential for cleaning teeth and remineralizing them. Dentists should be informed about the risks of antidepressant use to prevent these issues.