Researchers at UNC-CH have developed a gene therapy method that targets specific types of cells, avoiding the less effective 'shotgun' approach. The technique successfully corrects genetic defects in primitive stem cells, which can be used to treat inherited blood disorders like hemophilia and non-inherited illnesses such as cancer.
Researchers found an immune molecule that kills damaged cells indirectly by closing receptors to a life-saving protein, shedding new insight on neurodegenerative diseases such as Alzheimer's and stroke. The findings could lead to targeted treatments for brain injuries and diseases involving neurodegeneration.
Researchers are using naturally occurring microbes to clean radioactively contaminated walls and ceilings at a shut down reactor in the UK. The technology removes surface contamination through a microbial decontamination process, significantly reducing waste treatment costs and improving personnel safety.
Researchers at the University of Iowa have identified a complex domino effect that causes cardiomyopathy in limb-girdle muscular dystrophy (LGMD). The study suggests that drug therapy targeting vascular smooth muscle could prevent or stabilize cardiomyopathy in some cases of LGMD.
A Harvard Medical School study reveals that physician guidelines for estrogen replacement therapy fail to address women's concerns and needs. Researchers found that patients value healthcare provider opinions, media influences, and friend opinions when making decisions about hormone replacement therapy.
Researchers have identified a structural anomaly in the Taq DNA polymerase enzyme that hampers its performance in DNA sequencing. By modifying this anomaly, scientists created an improved version of the enzyme, which increases sequencing speed and reduces errors.
A recent study found that the majority of nurses in hospitals and nursing homes are ill-prepared to care for the elderly, with many having no formal training in gerontology. The study calls for increased geriatric education in nursing programs to ensure optimal care for older adults, who account for a growing share of healthcare needs.
Andrew Hamilton, an organic chemist at Yale University, is being honored with the American Chemical Society's Arthur C. Cope Scholar Award for his work on designing molecules that can control cell growth in cancer treatment. His research focuses on targeting a protein called Ras, which accounts for over 30% of all cancers.
Researchers at Washington University School of Medicine have identified a potential new approach to treating glaucoma by inhibiting an enzyme that produces excessive nitric oxide, leading to cell damage. The study found that rats with elevated eye pressure lost less than 10% of their retinal ganglion cells when treated with the inhibitor.
The American Association for the Advancement of Science (AAAS) is hosting a public forum to gather public comment on stem cell research recommendations. The event will feature a panel discussion with experts from various fields, including science, ethics, and policy.