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Science News for June 8, 1999


Postmenopausal hormone replacement therapy linked to increased risk for certain types of rarely occurring breast cancer

A study by Northwestern University and the Mayo Clinic found that postmenopausal hormone replacement therapy increases the risk for specific types of breast cancer with favorable prognoses, particularly invasive ductal or lobular carcinoma. The risk is higher among women who used hormone replacement therapy for five or fewer years.

SourceNorthwestern University·JournalJAMA·DateJun 8, 1999

New mechanism explains Alzheimer's damage

Researchers found a new mechanism explaining how Alzheimer's disease damages the brain by producing hydrogen peroxide from oxygen, a toxic agent that can cause brain damage. The discovery provides a potential target for new drugs to treat Alzheimer's, which affects four million Americans.

SourceAmerican Chemical Society·JournalThe Journal of Biochemistry·DateJun 8, 1999

Cedars-Sinai Medical Center study identifies for the first time a molecular mechanism behind hormonal response to stress

A Cedars-Sinai Medical Center study has discovered a molecular mechanism behind hormonal responses to stress, involving leukemia inhibitory factor (LIF) and its regulation of the pituitary gland. This finding provides new insights into the body's response to stress and sepsis.

SourceCedars-Sinai Medical Center·JournalProceedings of the National Academy of Sciences·DateJun 8, 1999