Researchers at UNC Health Care have identified the crystal structure of a key protein interaction involved in cancer cell spread. This discovery aims to develop targeted therapies against invasive cancer cells with minimal side effects.
Jonathan Scheuer, pioneer in marine natural products research, is being honored for his work on developing treatments for incurable diseases. His research has led to the discovery of compounds like Kahalalide F, a potential cancer treatment.
University at Buffalo chemists found that nitric oxide is highly reactive with ethanol, making it a potentially more insidious pollutant. The study's findings provide new insights into how solvation affects chemical reactions and could help scientists better tailor lab experiments.
A growing global problem: Bacterial resistance to antibiotics is on the rise, with penicillin and macrolide antibiotics showing high levels of resistance. Telithromycin, a new ketolide antibiotic, has shown promise in combating treatment-resistant respiratory tract infections.
A recent UT Southwestern Medical Center study found that substituting regular margarine for butter can lower LDL cholesterol levels by up to 11% in adults and 9% in children. The study also confirmed that a margarine-based diet is healthier than a butter-based diet, reducing heart-disease risk.
A comprehensive study found that women who underwent tubal sterilization have no greater risk of menstrual abnormalities than those who did not. However, the study also reported a secondary finding of reduced menstrual pain and bleeding among sterilized women, which may be due to chance or unknown factors.
A new study led by UCSF researchers suggests that prescribing beta-blockers to most people who have had heart attacks could save seven times more years of life than mammography screening over 20 years. The study projects 4,000 lives saved and 3,500 averted heart attacks at a reasonable cost.
A study analyzing health data from nearly 3,000 patients found that obesity is associated with lower physical functioning levels and worse perceptions of health. Patients with higher BMI values were also limited in basic activities due to their weight, according to lead author David A. Katz.
Ecologists developed a new mathematical model that uses just a few factors to capture the essentials of predator-prey battles, predicting population cycles and dynamics. The model was tested in a laboratory microcosm with single-celled algae and microscopic animals, showing results consistent with predictions.
A Phase II study demonstrates the efficacy of non-surgical radiologic intervention using heat in treating kidney cancers. Dr. Jonathan Lewin has successfully 'ablated' tumors in six patients with no recurrence, surpassing the normal three- to-six-month recurrence rate.
The Human Genome project has a limited representation of global genetic diversity due to an inadequate sample size from sub-Saharan Africa. This exclusion ignores the worldwide genetic variation and evolutionary history of the human species, according to anthropologist Todd R Disotell.
A new technique called constraint-induced movement (CIM) therapy has been shown to improve motor functions in stroke patients, even after 14 days. CIM therapy encourages use of the impaired arm and has been found to improve overall arm strength and coordination.