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Science News for February 14, 2000


Study: exercise, even without weight loss, is good for the heart

A recent study by Duke University researchers found that moderate exercise alone can improve cholesterol levels and reduce body fat in mildly obese people, regardless of weight loss. The study showed significant improvements in cardiovascular risk factors, including a decrease in LDL cholesterol and an increase in HDL cholesterol.

SourceDuke University Medical Center·JournalJournal of Clinical Exercise Physiology·DateFeb 14, 2000

UCSF study finds genetic link between initial early stage breast cancer cells and disease recurrences

A recent study by UCSF researchers has found a strong genetic link between early stage, non-invasive breast cancer cells and disease recurrences. The study suggests that second tumors are caused by residual cells left over from the primary lesion, highlighting the importance of wide surgical margins to prevent recurrence.

SourceUniversity of California - San Francisco·JournalJNCI Journal of the National Cancer Institute·DateFeb 14, 2000

Swaziland to educate and assist people living with HIV/AIDS with grant to train Swaziland's 2,500 community health and social welfare motivators

The program will develop a curriculum for Community Health and Social Welfare Development Motivators to provide basic nursing tasks and support behavioral change in families and communities. The initiative aims to reduce stigma associated with HIV/AIDS and expand upon the work of various public and private organizations.

Too much fat in heart cells can cause heart failure, researchers find diabetes drug may help

A study of genetically obese rats revealed that an overabundance of fat can collect in heart cells and cause them to die, leading to heart failure. The researchers found that a diabetes drug prevents this damage by oxidizing the fat so it burns up rather than accumulating and causing heart-cell death.

SourceUT Southwestern Medical Center·JournalProceedings of the National Academy of Sciences·DateFeb 14, 2000

Should people with type 2 diabetes get their eyes screened every year? New study says it's not necessary for most patients

Researchers suggest that a significant majority of people with type 2 diabetes derive little additional benefit from annual eye screening. Instead, every other year or even every third year screening is nearly as beneficial and more cost-effective. This finding could lead to a shift in recommendations for optimal screening intervals.

New treatment approach might prevent serious complications of liver disease

Researchers identified a new treatment approach that could prevent life-threatening complications of alpha-1-antitrypsin deficiency. A drug called 4-phenylbutyric acid (PBA) improved secretion of mutant protein, increasing levels by 20% to 50%. This approach may also help patients with other diseases such as Alzheimer's and Parkinson's.

SourceWashU Medicine·JournalProceedings of the National Academy of Sciences·DateFeb 14, 2000