Researchers found that mice lacking centromere protein B (CENP-B) suffer from reproductive failure due to defects in the uterus. The study suggests CENP-B plays a role in cell divisions that remodel the uterine lining during estrus and pregnancy.
A new study led by UCSF scientists found that giving patients more oxygen during and after anesthesia can cut the rate of surgical wound infections in half. The increased oxygen improves immune cells' ability to fight infections, reducing hospitalization time and costs.
Researchers at Thomas Jefferson University have used gene therapy to replace a damaged Rb2 gene with a healthy version, dramatically shrinking lung cancer tumors in mice. The study provides direct evidence that Rb2 is a tumor suppressor and demonstrates its potential as a target for human gene therapy trials.
A two-year public service project will screen people in 14 western NC counties for hemochromatosis, a genetic illness causing excessive iron absorption. The project aims to increase awareness and identify individuals at risk before chronic health conditions develop.
The new guidelines take into account the availability of new anti-retroviral drugs and expanded therapy choices. Recommendations include initiating therapy based on viral load and CD4 cell count, choosing individualized regimens, and monitoring treatment response with CD4 and HIV RNA levels.
A study by Washington University's Air Quality Laboratory found that rural vehicles emit between 200-300 milligrams of particulate matter per mile traveled, while urban vehicles emit between 30-40 milligrams. This measurement, known as ppvm, could help environmental agencies better address air quality challenges.
Researchers at Oregon Health & Science University have successfully cloned an identical monkey named Tetra using embryo splitting. This breakthrough method shows promise for accelerating discoveries in human diseases like Alzheimer's, AIDS, and cancer.
Researchers successfully engineered a genetic toggle switch to control the activity of genes between stable on and off states. The toggle represents core technology for genetic control devices with potential applications in diabetes, biological warfare agent detection, and cell-based computing.
Researchers at the University of Toronto have found a cellular communication method in the brain that could lead to improved treatments for schizophrenia and addiction. The study demonstrated how proteins can modify each other's function, including the ability of neurons to accept or reject dopamine and other neurochemicals.
Rescuers can locate avalanche victims four times faster using a robotic swarm search technique. Researchers at Sandia National Laboratories developed a computer program that enables humans to find buried skiers using mini-robots and simple radio equipment.
Methylnaltrexone reverses opioid-induced constipation in over 90% of patients, providing relief from debilitating symptoms. The drug is designed to block morphine's effects on gut motility without interfering with pain relief.
A new study links human breast cancer to the mouse mammary tumor virus, proposing that humans acquire the virus from infected mice. The authors found a similar viral sequence between human breast cancer and mouse mammary tumor virus, suggesting a potential preventive vaccine.