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Science News Archive 2001 - Page 43


Page 43 of 47

Fertility experts urge clinics to consider ‘natural cycle’ IVF instead of routine use of ovarian stimulants

A study by UK fertility experts found that natural cycle IVF can achieve comparable results to conventional treatment in 60-70% of cases, while reducing costs and risks. The approach is suitable for women with regular menstrual cycles and fallopian tube problems, but not for those with irregular ovulation or ICSI requirements.

Untangling prostaglandin signaling

A study by Stock et al. reveals that genetic disruption of the PGE2 receptor EP1 significantly reduces pain behavior and blood pressure responses to inflammation. The findings suggest that NSAID treatment's analgesic effect can be explained by inhibition of signaling through this single receptor type.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJan 30, 2001

O.R. study suggests safety benefits from free flight routings.

A preliminary study published in Operations Research found that free flight routing could lead to a significant reduction in mid-air collision risk, with a potential safety dividend of up to 69%. The study also suggests that shortened flight paths could result in reduced fuel consumption and increased flight frequencies.

Gene study to unlock causes of stroke

Researchers will examine genetic factors that might predispose people to ischaemic stroke, using a novel molecular strategy and data from 500 patients. The study aims to identify genes involved in stroke and develop new treatments, which could increase protection against subsequent strokes.

Novel route to lupus-like disease in mice

Researchers at Howard Hughes Medical Institute have identified a link between faulty glycan construction and the onset of autoimmune diseases like lupus. Knocking out a gene involved in modifying sugar molecules on cell surfaces led to mice developing lupus-like abnormalities, including inflamed kidneys and autoreactive antibodies.

SourceHoward Hughes Medical Institute·JournalProceedings of the National Academy of Sciences·DateJan 29, 2001

Cancer's penchant for developing drug resistance is a result of chromosome reassortment, UC Berkeley scientist proposes

A UC Berkeley scientist proposes that chromosome reassortment, rather than genetic mutations, is the cause of cancer's tendency to develop drug resistance. This theory suggests aneuploid cells, with abnormal numbers of chromosomes, are more prone to producing drug-resistant cancer cells.

SourceUniversity of California - Berkeley·JournalProceedings of the National Academy of Sciences·DateJan 28, 2001

Mouse provides clues about chronic pain

A protein called NR2B makes mice more aware of minor pain for longer periods of time, a phenomenon that mimics what happens in people with chronic pain. The researchers suggest that interfering with NR2B in humans might be a strategy for treating chronic pain.

SourceWashU Medicine·JournalNature Neuroscience·DateJan 27, 2001

Age matters when exercising in hot climates

Research by Penn State specialist Dr. W. Larry Kenney highlights the strain on older hearts when exercising in heat stress, increasing mortality rates among those over 65. Regular exercise and hydration countermeasures can mitigate effects, but individual factors like fitness level and medication impact thermoregulation.