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Science News for August 27, 2001


Does chromosome 4 hold the secret to human longevity?

A genome-wide study of 308 long-lived individuals revealed a significant correlation between allele sharing on chromosome 4 and longevity. This suggests that the region may contain genes influencing human lifespan, with potential applications in preventing age-associated diseases such as heart disease and Alzheimer's disease.

SourceHoward Hughes Medical Institute·JournalProceedings of the National Academy of Sciences·DateAug 27, 2001

First-ever published study of moderate to severe Alzheimer's disease patients taking Aricept (r) shows significant treatment benefits in cognition, daily living activities and behavior

A 24-week study found consistent benefits of ARICEPT in patient function, cognition, behavior, and activities of daily living. The medication showed statistically significant overall improvement vs. placebo in behavioral disturbances associated with Alzheimer's disease.

SourcePorter Novelli·JournalNeurology·DateAug 27, 2001