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Science News for January 11, 2001


Researchers design new way to squelch errant enzymes

Scientists have developed a novel approach to inhibit protein kinase enzymes, which play a crucial role in triggering cancers, hardening of the arteries, and autoimmune diseases. The researchers' bisubstrate analogs effectively prevent these enzymes from working, offering a promising therapeutic strategy for various diseases.

SourceJohns Hopkins Medicine·JournalNature Structural & Molecular Biology·DateJan 11, 2001

Stalking a Parkinson’s protein

Researchers have discovered a crucial genetic element that regulates alpha-synuclein protein activity, which is involved in both inherited and non-inherited forms of Parkinson's disease. By identifying this element, scientists hope to gain insights into the underlying mechanisms of the devastating disease.

SourceCold Spring Harbor Laboratory·JournalGenome Research·DateJan 11, 2001