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Science News for December 17, 2002


Other highlights of the December 18 JNCI

Researchers investigated the association between alcohol consumption and lung cancer risk, finding no statistically significant link. The Journal of National Cancer Institute also published studies on body surface area-based dosing for anticancer drugs and carbohydrate binding protein's potential to inhibit tumor growth.

SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateDec 17, 2002

NHLBI study finds traditional diuretics work better than newer medicines for treating hypertension

A recent NHLBI study found that traditional diuretics are more effective than newer antihypertensive medications in treating high blood pressure and preventing cardiovascular events. The study, which involved over 42,000 participants, showed that diuretics reduced the risk of heart attacks and strokes by 34% compared to the other groups.

Increased bone mass in a calcitonin knockout mouse full of surprises

Researchers discovered that calcitonin knockout mice have greater bone mass and increased bone formation, suggesting a novel function for the calcitonin gene product. This finding has implications for preventing bone loss associated with estrogen deficiency, potentially leading to new treatments for post-menopausal osteoporosis.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateDec 17, 2002

JCI table of contents, December 15, 2002

Research reveals that mice without the calcitonin gene exhibit greater bone mass and formation, suggesting a novel function for this hormone. This discovery opens up new avenues for preventing bone loss associated with estrogen deficiency.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateDec 17, 2002