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Science News for December 23, 2002


World Trade Center dust analysis offers good news for New Yorkers

Researchers analyzed debris from the collapsed towers and found no high levels of pesticides, polychlorinated biphenyls or other persistent organic pollutants. The study estimated that 100-1000 tons of polycyclic aromatic hydrocarbons were present in lower Manhattan dust, but these particles were too large to be inhaled deeply.

SourceAmerican Chemical Society·JournalEnvironmental Science & Technology·DateDec 23, 2002

Cell division required, twice before fat cells mature

Cell division is necessary for fat cells to mature, according to a new study. The researchers found that primitive fat cells need to divide at least twice before they can store fat, and that interfering with this process could prevent the formation of new fat cells.

SourceJohns Hopkins Medicine·JournalProceedings of the National Academy of Sciences·DateDec 23, 2002
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Simpler therapies may help improve outcomes for HIV patients

A study found that HIV patients with cognitive impairment who took medications three times a day had lower adherence rates than those on simpler schedules. Researchers suggest giving simpler dosing to help patients stick to their medication schedules.

SourceAmerican Academy of Neurology·JournalNeurology·DateDec 23, 2002

UCLA/Caltech scientists develop new gene therapy approach

Researchers have successfully created a delivery system using a vehicle derived from HIV itself to introduce synthetic siRNAs into human cells. This approach aims to prevent HIV infection by knocking out the CCR5 receptor, which is found on T-cells and plays a role in immune function.

SourceUniversity of California - Los Angeles·JournalProceedings of the National Academy of Sciences·DateDec 23, 2002

Easier drug schedules help cognitively impaired HIV patients

A study of 137 adults with HIV found that simplifying their medication regimens can significantly improve adherence, particularly for those with memory and attention problems. The study suggests a two-way relationship between missed doses and disease progression, highlighting the need for more effective treatment strategies.

SourceVeterans Affairs Research Communications·JournalNeurology·DateDec 23, 2002

Neuropsychiatric lupus research receives a boost

New studies aim to improve diagnosis and treatment for patients with Neuropsychiatric-SLE, a major cause of death among people with lupus. Researchers will investigate the underlying causes of NP-SLE using new tools and approaches.

SourceNIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases·DateDec 23, 2002

USC researchers use gene therapy to prompt mouse cells to produce human collagen

USC researchers have successfully used gene therapy to prompt mouse cells to produce human collagen, a crucial step towards treating patients with dystrophic epidermolysis bullosa. This breakthrough could lead to the development of new treatments for this debilitating skin condition, which causes blisters and permanent scars.

SourceUniversity of Southern California·JournalNature Genetics·DateDec 23, 2002
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