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Science News for February 6, 2002


Duke researchers identify the mechanisms by which drug combinations kill fungal infections

Researchers at Duke University Medical Center have traced cellular pathways that enhance the action of antifungal drugs used to treat fungal infections in people with compromised immune systems. Combining fluconazole with cyclosporin or FK506 was found to potently kill fungal cells, and the team elucidated the molecular targets involved.

SourceDuke University Medical Center·JournalThe EMBO Journal·DateFeb 6, 2002

American Thoracic Society Journal news tips for February (first issue)

A new study found that caregivers with higher perceived stress levels had infants who experienced more wheezing episodes during the first 14 months of life. Additionally, exposure to German cockroach allergen was associated with increased risk of asthma attacks in susceptible children. Researchers also developed a molecular model of th...

SourceAmerican Thoracic Society·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateFeb 6, 2002

Potential allergy vaccine boosts hope for sufferers

Researchers at the University of Melbourne have developed a potential allergy vaccine using a modified rye grass protein that reduces allergenic response while boosting immune system. The vaccine, delivered in its pure form, may significantly reduce risk of anaphylactic shock and increase immunotherapy efficacy.

SourceUniversity of Melbourne·JournalEuropean Journal of Immunology·DateFeb 6, 2002