A meta-analysis by Ohio State University researchers found that higher CO2 levels increase crop yields, but decrease the nutritional value of crops. While plants grown in high-CO2 conditions produce more seeds and individual seed weight, they contain less nitrogen.
A team from U-M School of Nursing developed HANDS, a program to track nurses' observations and treatments. The system aims to provide healthcare professionals with a holistic view of patients' conditions.
A Yale University study found that a 6-month exercise program improved muscle strength, balance, and mobility in physically frail elderly people. The program also reduced disability scores by 45% and nursing home use among participants.
The Leukemia & Lymphoma Society has awarded a $7 million grant to Fred Hutchinson Cancer Center researchers to develop new, more tolerable and effective therapies for blood cancers. The project aims to harness the immune system to selectively target cancer cells using immune cells or antibodies armed with toxic agents.
The Lancet Oncology editorial discusses the EPA's 10-year report on diesel exhaust fumes' toxic effects, emphasizing public health implications. The article also reviews mathematical models identifying breast cancer risk factors and explores chemoprevention strategies.
Researchers at Duke University Medical Center found that using Doppler technology to guide fluid administration during major surgery improves outcomes. Patients who received Doppler-guided care experienced shorter hospital stays, faster recovery, and less postoperative nausea and vomiting compared to those who received conventional care.
The study identifies five insulin-like peptides that regulate mosquito life cycle and disease transmission, providing new targets for genetic interference. The discovery could lead to the development of more effective control methods against malaria.
Sporn's groundbreaking research on chemoprevention has revolutionized the field of cancer prevention, exploring novel approaches to prevent or treat cancer. His work has led to strategies with vast potential for reducing cancer incidence and death, and continues to inspire new directions in cancer prevention research.
The Fenniri team has discovered a new class of nanotubes formed from synthetic organic molecules, enabling complete control over their formation and properties. These nanotubes can be customized to possess different physical and chemical properties, making them suitable for various industrial applications.
Researchers have identified a specific gene mutation that confers chloroquine resistance in Plasmodium falciparum malaria parasites, allowing scientists to develop targeted treatments, and also increasing susceptibility to artemisinin and quinine.
A new web-based database provides researchers with access to the Plasmodium genome, enabling them to examine chromosome organization, scan for genes and predict protein structures. The database aims to speed up research and discovery in malaria combat, leveraging global collaboration among diverse scientists.
Researchers have identified 276 G protein-coupled receptors in the Anopheles mosquito genome, including 155 external chemosensory receptors that allow female mosquitoes to detect humans and other mammals by taste or smell. The discovery provides a new approach to studying mosquitoes and reducing the spread of malaria and other diseases.
The consortium will analyze patient records to identify clusters of health complaints associated with bioterror agents. The system aims to detect unusual increases in people contacting help lines or primary care doctors, enabling a rapid response to public health officials.
Researchers discovered a blocking enzyme that reduces anxiety without sedation, improving cognitive abilities and alertness. The study suggests a new route for treating anxiety without the side effects of existing anti-anxiety drugs.
The Institute for Genomic Research has published a paper analyzing the genome of Plasmodium falciparum, a malaria parasite. The analysis identified about 200 genes producing proteins involved in immune evasion and revealed metabolic pathways, including enzymes that could be targeted by chemotherapy.
The newly-sequenced Anopheles gambiae genome holds promise for developing new insecticides, transmission-blocking vaccines, and mosquito repellants. Researchers identified genes involved in the mosquito's ability to host the malaria parasite and located targets for new insecticides.
Researchers have found genes in Anopheles mosquitoes that enable them to resist infection by the deadly malaria parasite. The discovery could lead to new strategies to prevent malaria transmission by spreading the parasite-blocking genes among mosquito populations.
Scientists study emesis in genetically engineered mice lacking specific PDE4 subtypes and infer that inhibition of PDE4D mediates nausea. The discovery could lead to the development of selective PDE4 inhibitors with anti-inflammatory effects, reducing side effects in humans.
Researchers at Cold Spring Harbor Laboratory found that visual stimulation causes neurons to sprout new branches, a process that requires increased activity of certain proteins and decreased activity of others. The study provides insights into how visual stimulation guides the development of normal brain architecture.
Studying genetically engineered mice that lack specific PDE4 subtypes, researchers found that inhibition of PDE4D mediates much of the emetic response. The study aims to develop subtype-specific inhibitors effective in airways without affecting other tissues.
Mice lacking a specific gene have reduced anxious behavior and increased sensitivity to brain's own endogenous neurosteroids. The findings suggest PKCe as a possible target for developing novel therapeutics for anxiety treatment.
A new UCSD study found that counseling services provided through state-funded quitlines significantly increase abstinence rates at 1, 3, 6 and 12 months. The research suggests that these programs can help a higher number of long-term quitters compared to those who do not use such services.
Researchers have discovered transposable elements in the malaria mosquito genome, which can be used to introduce new genes to block disease transmission. These elements can also serve as markers to distinguish between populations of mosquitoes with varying resistance levels.
A study of nearly 133,500 female California teachers found a 51% higher rate of breast cancer and 72% greater risk of endometrial cancer compared to comparable women. Researchers believe lifestyle and environmental factors may contribute to the increased risk.
A team of scientists has discovered that an Antarctic ice stream has reversed its flow over the past 250 years, a phenomenon that may be linked to long-term climate change. The study reveals that changes in the ice sheet's configuration have led to a shift in the flow direction, potentially impacting global sea levels.
A team of researchers from Vanderbilt University identified 276 genes in the Anopheles gambiae genome that code for G-protein-coupled receptors essential to the mosquito's senses. The study found 79 genes involved in its sense of smell and 72 in its taste, shedding light on the insect's strong preference for human hosts.
Scientists have identified a potential new target in the brain for anxiety-reducing medications, which may provide less disruptive alternatives to existing sedatives. By inhibiting a specific enzyme protein kinase C (PKC-epsilon), researchers hope to develop new treatments that can modulate GABA function without addictive side effects.
A study published in The New England Journal of Medicine found that a prehabilitation program improved balance, muscle strength, and mobility in physically frail elderly individuals. The program, which included physical therapy and resistance band exercises, significantly reduced disability scores compared to a health education group.
A new computer model suggests that regular visual inspections every five years can save lives and reduce costs compared to DNA testing or traditional Pap smears. In Thailand, where cervical cancer is a major public health concern, this low-tech screening strategy could be an effective and affordable solution.
Researchers have successfully synthesized clusters of fluorine-containing dendritic polymers that organize into tiny supramolecular cylinders. These nanocylinders display promising optoelectronic properties and can be used as donor- or acceptor groups, enabling the creation of novel electronic devices.
Researchers at Memorial Sloan Kettering Cancer Center discovered that cancer cells containing high levels of Myc protein cannot activate p21 gene production, leading to cell death. The study's findings suggest a potential strategy to increase chemotherapy effectiveness by favoring apoptosis over citostasis.
Two robotic gliders, Slocum Glider and Seaglider, will be tested operationally off Southern California this winter. The gliders harness changes in buoyancy or temperature layers to collect data on ocean currents, salinity, and biological sounds.