A novel gene therapy technique developed by Stanford researchers allows for the integration of large genes into human chromosomes, enabling continuous production of proteins. This technique has the potential to treat a variety of diseases, including Duchenne's muscular dystrophy and cystic fibrosis.
Researchers have identified a genetic link between macrophage scavenger receptor-1 (MSR1) and increased risk of prostate cancer. MSR1 mutations were found in approximately 12.5% of African American men with prostate cancer, compared to 1.8% without the disease.
The study identified specific genes regulated by Nrf2 in response to sulforaphane, a compound found in broccoli that can annihilate a broad spectrum of carcinogens. By understanding how this process works, researchers may develop new cancer preventive agents.
A research team led by Wake Forest and Johns Hopkins universities found that mutations in the MSR1 gene are associated with an increased risk of aggressive prostate cancer, particularly in African-American men. The study identified seven potentially important mutations of the MSR1 gene, including one that leads to rapid metastasis.
A recent study found that almost 33,000 pregnant women were involved in car crashes every year between 1995 and 1999. The researchers also discovered that younger women, aged 20-29, are more likely to be involved in car crashes during their peak childbearing years.