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Science News for December 29, 2003


Anthrax toxin inhibitor identified

Researchers at Harvard Medical School have identified an anthrax toxin inhibitor that could lead to more effective therapy for the deadly agent. The discovery, made using a 'mixture-based peptide library' technique, reveals new approaches to design better inhibitors that might prove effective in clinical use.

SourceHarvard Medical School·JournalNature Structural & Molecular Biology·DateDec 29, 2003

Smart materials for a next-gen vehicle

The Office of Naval Research is developing new materials to increase the survivability of future Marine Corps vehicles. Six contractors have developed new material concepts, with three selected for Phase 2 contracts. Lightweight high-strength composite materials and embedded sensors will be integrated into a vehicle demonstrator.

SourceOffice of Naval Research·DateDec 29, 2003

Navy enlists microbes to cut costs

The Navy is using microorganisms to produce a key missile propellant, butanetriol, which could reduce production costs and environmental impact. The process involves modifying bacteria to convert sugars into the synthetic material, allowing for a more efficient and environmentally friendly alternative.

SourceOffice of Naval Research·JournalJournal of the American Chemical Society·DateDec 29, 2003

'Smart bomb' delivery destroys tumors in mice

Scientists have developed a method that uses allicin, found in garlic, to selectively kill cancer cells in mice. The method involves injecting an antibody and enzyme combination that targets specific receptors on cancer cells, triggering the production of lethal allicin molecules that destroy tumors while leaving healthy cells intact.

SourceAmerican Committee for the Weizmann Institute of Science·JournalMolecular Cancer Therapeutics·DateDec 29, 2003
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Genetic master switch sends bacteria toward 'seafood dinner'

Researchers identified a genetic master switch that controls bacterial consumption of chitin, a key component of ocean debris. The discovery sheds light on the process by which bacteria break down tough material and turn it into food, preserving ecological balance in the ocean.

SourceJohns Hopkins University·JournalProceedings of the National Academy of Sciences·DateDec 29, 2003

Blog, Blog, Blog

The Navy is testing a blog as part of the Defense Acquisition Incentive-Net Centricity (RAI-NC) initiative to speed up the exchange of information on new defense technologies. The pilot program, developed by Traction Software, enables users to post proprietary data and distribute general information among team members.

SourceOffice of Naval Research·DateDec 29, 2003

Midlife brain crisis spawns late-life Alzheimer's

A novel model of human brain aging identifies midlife breakdown of myelin as a key factor in the onset of Alzheimer's disease later in life. Lifestyle changes, hormone replacement therapy, education, and treatment with common medications may help prevent myelin degradation.

SourceUniversity of California - Los Angeles·JournalNeurobiology of Aging·DateDec 29, 2003

New study identifies inhibitor of anthrax toxin

Researchers have identified a potential inhibitor of anthrax toxin, which could lead to more effective therapy for the deadly agent. The study's findings suggest that combining antibiotics and protease inhibitor drugs may provide a cost-effective solution for treating inhalational anthrax.

SourceBeth Israel Deaconess Medical Center·JournalNature Structural & Molecular Biology·DateDec 29, 2003
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