Researchers at UIC College of Medicine identified 57 genes involved in cell proliferation, including some not previously known to play a role in cancer cell growth. The study found that certain fragments inhibited the multiplication of breast cancer cells by shutting down genes necessary for cell growth.
Researchers propose alternative testing methods, such as heat-denatured p24 antigen tests and flow cytometric quantitation of CD4 T-cells, to measure progress in the war against HIV/AIDS. These affordable alternatives provide an indication of treatment response and help public health officials assess the effectiveness of their efforts.
A mandated food additive to combat high fetal development risks may inadvertently harm seniors due to low levels of vitamin B-12. The condition, which affects nearly half of US deaths annually, has been linked to cardiovascular diseases and mental confusion in some cases.
A new study investigates the relationship between pain and selected medications, using genotyping to predict clinical outcomes and adjust drug therapy. By analyzing plasma concentrations of analgesics metabolized by CYP2D6, researchers aim to improve pain management therapy and reduce adverse effects.
RHESSI observations show that microflares, tiny explosive events on the sun, provide a significant portion of heat in the corona. The satellite's findings suggest that microflares could be key to understanding solar flares and coronal mass ejections, which affect Earth's space weather.
A new study shows that a derivative of green algae Chlorella pyrenoidosa improves the body's immune response to influenza vaccines. The study found significant increases in antibody responses after supplementation with two different doses of the extract, with no adverse effects reported.
The CDC recommends testing C-reactive protein levels in patients with intermediate risk of cardiovascular disease, and in those with acute coronary syndromes or stable coronary disease. The guidelines also emphasize the importance of standardizing laboratory test results to accurately measure hsCRP levels.
Researchers highlight the growing concern of male osteoporosis, emphasizing genetic predispositions and secondary risk factors such as alcohol consumption and malnutrition. Dr. Rosen recommends early bone density testing for men over 55 with unexplained height loss or fracture history to identify potential treatment options.
The US is struggling with chronic poverty, slow economic growth, and insecure access to healthcare, ranking 27th globally. Africa is in dire straits, with many countries facing concentrated poverty, weak institutions, and repeated economic failure.
The authors conclude that bodychecking should be banned in hockey until players are at least age 17 or 18 years old due to increased concussion and injury risks. Most physical growth occurs during this period, making it a critical time for protecting young athletes.
A novel coronavirus has been confirmed as the primary causal agent of SARS, according to a study. The virus was found to infect the lower respiratory tract, leading to severe lung damage and disease symptoms. The discovery was made through laboratory studies of patients and experimental infections in macaques.
Researchers used banded water snakes to compare traditional testing methods with nonlethal samples, finding promise in laser ablation for conservation-minded eco-toxicological studies. The study was conducted at SREL on the Savannah River Site, partially funded by a grant from DOE.
Lab Tests Online offers a comprehensive resource for patients seeking information on lab tests, including explanations of test results and personalized responses from clinical laboratory scientists. The site also integrates with other reputable sources like NIH's Medline Plus.
Animal studies found major malformations in the epididymis, a leading deformity caused by antiandrogen chemicals disrupting fetal reproductive development. Exposures to DBP and linuron during critical windows of in utero development can lead to infertility and testicular atrophy.
Early detection and treatment of allergies can prevent serious complications and modify the progression of pediatric allergies. A specific IgE blood test can accurately diagnose atopy and guide treatment, including avoidance therapy and medication.
A recent study published in the Canadian Medical Association Journal investigated the effects of a Chlorella-derived dietary supplement on immune function and influenza vaccination. The results showed no significant increase in antibody response to the flu vaccine overall, although some increase was seen in participants aged 50 to 55.
A study by the American Academy of Neurology found that black children, particularly boys, have a higher risk of stroke compared to their white counterparts. The annual stroke incidence rate among children was 2.3 strokes per 100,000, with ischemic stroke accounting for 51% of cases.
Astronomers have discovered four massive stellar clusters with stars as massive as 120 solar masses in the Milky Way's W49 molecular cloud. This reveals the true sources of enormous energy powering a giant HII region, solving decades of speculation.
The completed genomic sequence of Fusarium graminearum, a fungus causing widespread damage to wheat and barley crops, offers a roadmap for developing new control methods. Researchers will focus on understanding gene function to unravel mechanisms to combat this devastating pathogen.
Researchers at Johns Hopkins University successfully redesigned software for the FUSE satellite's gyroscopes, enabling precise control and reducing reliance on faulty components. The new system has shown improved performance, even surpassing traditional methods in certain situations.
A new test method aims to predict which early-stage cancer patients are at high risk for relapse, allowing for more precise treatment decisions. By analyzing apoptosis proteins in patient tumors, researchers hope to identify molecular and genetic signatures that indicate the likelihood of cancer recurrence.
Researchers have identified new serum biomarkers for ovarian cancer, which may be used in conjunction with existing methods such as CA125 marker and ultrasound to improve diagnosis. These newly discovered markers show promise in detecting the disease at an early stage, leading to better treatment outcomes.
A three-week training program based on National Reading Panel principles improved brain activation patterns and reading performance in children with dyslexia. Dyslexic children showed significant improvements after the program, demonstrating that instruction can strengthen existing brain circuits rather than rewiring them.
The growing trend of consumer ordering lab tests is driven by convenience and a desire for control over healthcare. Key findings include that middle-aged or younger groups are most interested in DAT, with income brackets, health status, and insurance playing significant roles in adoption.
A new bead-array test can identify the 25 most common cystic fibrosis mutations in just 15 seconds, enabling potential parents to make informed decisions about conception and treatment options. The test requires only genomic DNA from a patient and uses a single reaction to screen for all 31 CF mutations.
A study found that HIV treatment costs increased significantly between 1995 and 2001, driven by the use of highly active antiretroviral therapy (HAART). Despite this, overall medical care costs remained relatively stable during the same period.
A blood test could identify biological markers that indicate the onset of a heart attack or stroke, leading to life-saving intervention. Researchers are developing a diagnostic tool using 'sick cells' markers, which may be available in three to five years.
A team of researchers analyzed ancient DNA from Joseph Merrick, aka the Elephant Man, to uncover the cause of his severe deformities. The study revealed that Merrick likely suffered from Proteus syndrome, while some experts suggest he may have had both Proteus syndrome and neurofibromatosis.
Pediatric food allergies affect 6-8% of infants/children, primarily milk. Diagnosis involves a complete work-up, including history, physical, laboratory evaluation, and biopsy. Treatment includes elimination diets, oral challenge testing, and treatment for severe reactions.
Researchers at Scripps Research Institute identify a single protein called Trif that associates with different receptors to detect pathogens, triggering immune reactions. The protein could be a potential target for intervening in diseases like sepsis.
Established educational websites dominate the e-learning market, prioritizing branding over content and interactivity. Despite potential for growth in home learning, government testing imperatives hinder innovation and competition.
Researchers discovered Trif, a critical transducer protein in the innate immune system, which mediates signals from both bacterial and viral infections. The protein's role sparks inflammation, making it an attractive target for drugs designed to combat runaway inflammation characteristic of infectious diseases.
Research by Debra Fischer and Jeff Valenti found a correlation between star metal abundance and planet formation, with metal-rich stars having a 20% chance of harboring planets. The data suggest that a threshold metallicity exists, favoring the formation of planetary systems in stars with higher initial metal content.
adidas introduces the JETCONCEPT bodysuit, which uses riblets to channel water and reduce drag, resulting in up to 3% increase in swimming performance. The suit was developed using technology from commercial aircraft, focusing on form drag rather than friction drag.
A new underground lab design has been completed by a collaborative project between the University of Washington and other institutions. The proposal establishes a main laboratory 7,400 feet deep and includes important operations on lower levels, with a focus on earth science and homeland security activities.
A recent US study found that parents' income and education significantly influence their teenager's likelihood of smoking. Adolescents from lower-income families, with less-educated parents, face a higher risk of smoking. The study suggests that tailoring smoking cessation programs for adults with low incomes or educational levels coul...
The Von Liebig Center has awarded funding to six University of California, San Diego (UCSD) faculty projects, focusing on commercializing innovative technologies. Two projects in the Bioengineering department aim to improve cooling fan efficiency and detect infectious agents using electric field-induced fluctuation methods.
Researchers are exploring alternative methods to conventional medical care for treating women's health issues, antibiotic-resistant infections, melanomas, and coronary heart disease. Nutritional and botanical therapies are being investigated as potential alternatives to traditional treatments.
A study led by Dr Jane Seymour found that older adults feel poorly informed about life-prolonging technologies, highlighting the need for better communication and public education. Participants emphasized trust, family involvement, and comfort as essential components of dignified end-of-life care.
Dr. Gonsalves' research discovery led to the development of enhanced papaya varieties resistant to ringspot virus, now widely planted and valued at over $14 million annually. His work has significantly impacted Hawaii's papaya production, saving the industry from devastating losses.
Researchers have identified key genes controlling skeleton development, including Hox10 and Hox11. These paralogous genes orchestrate construction of ribs, spine, and limb bones, with knocking out all forms revealing dramatic effects on development.
A UK study found no overall increased risk of death among women who used oral contraceptives, suggesting a potential lower mortality rate compared to non-users. Smoking was associated with a higher risk of death from all causes, particularly in heavy smokers.
A joint U.S.-Georgian team aims to develop a novel treatment against bacterial pathogens causing salmonella infection. The grant supports phage therapy research to prevent massive outbreaks and address growing antibiotic resistance.
Scientists at Vanderbilt University Medical Center have identified a new compound that activates glucokinase, an enzyme that regulates blood sugar levels. The compound has shown promise in improving insulin secretion and glucose usage in animals with diabetes, paving the way for potential clinical trials.
A gene variant appears to increase the risk of depression following stressful life events, according to a new study. People with the short version of the serotonin transporter gene were more likely to develop depression if they experienced multiple stressful life events.
The WHO 2003-2008 programme focuses on controlling HIV/AIDS, with a goal of 3 million people in developing countries receiving antiretroviral treatment by 2005. The initiative also aims to strengthen health systems and secure political backing for investment.
Researchers found that a specific gene variant interacts with stressful events to predict depression risk, with individuals carrying a short allele more vulnerable to depression after stress. The study's findings suggest new potential treatments and diagnostic techniques for millions of people worldwide affected by depression.
A recent study suggests that reducing the seizure-free interval from 12 to three months does not significantly increase total crashes. The researchers found that seizures-related crashes increased by 11, while deaths due to seizure-related crashes decreased.
A protein called PPAR-alpha is critical to this process, and the liver plays a key role in explaining the high incidence of diabetes and hypertension in obese individuals. The study suggests that understanding how steroids cause side effects may help prevent these disorders.
Researchers from Ames Laboratory aim to create efficient and selective nanocatalysts using mesoporous materials with controlled nanopores. The goal is to improve the selectivity of current mesoporous materials, which often require costly separation techniques.
A long-term study found that patients with leukoaraiosis, a condition characterized by scattered loss of white matter in the brain, were 1.5 times more likely to have a stroke than those without the condition. The risk was even higher for multiple strokes, leading to increased disability.
Researchers argue that improving current cars and environmental rules is more cost-effective than developing hydrogen fuel cells, which require significant investment in infrastructure. Increasing fuel efficiency or raising prices can achieve similar reductions in air pollution and greenhouse gas emissions without the need for new infr...
The team reconstructed a mass map of the galaxy cluster using NASA/ESA Hubble Space Telescope data, tracing dark matter's distribution with respect to galaxies. The study reveals that dark matter clumps together in certain regions, supporting the idea that clusters assemble through the merger of smaller groups.
Research found that salicylic acid in aspirin disrupts the stress system of S. aureus bacteria, reducing its ability to cause infection and adhere to host tissue. This finding offers hope for treating sepsis, a blood poisoning disease responsible for 750,000 US deaths annually.
A team of scientists has discovered that convection may also be occurring in the Irminger Sea east of Greenland, potentially forming deep waters. This finding places additional complexity on the climate system and suggests far-reaching implications for Labrador Sea Water formation.
A landmark study on lemur nutrition by Dr. Jennifer Campbell reveals that lemurs have different dietary requirements, with some eating leaves, fruits, insects, seeds, and nuts. Her research has led to the development of a proper diet for the animals, improving their health and reproductive success.
A study found that 90% of trachoma infections occur in children under 10 years old in Tanzania and The Gambia. The SAFE strategy, which includes surgery, antibiotics, facial cleanliness, and environmental improvements, is key to eliminating trachoma by 2020.
A study found that food diaries were more accurate than questionnaires in measuring fat intake, which could explain why no association was found between increased fat intake and breast cancer risk. However, the results highlight the importance of using reliable dietary assessment methods in nutrition research.
The HOME scientists used various instruments and equipment to track ocean energy and turbulence, finding that the Hawaiian Ridge is a site with vastly increased ocean mixing. They documented undersea internal wave energy enhanced 10 times at the ridge compared to normal open ocean areas.
Dr. Collier's pioneering research has led to significant advances in vaccine design and therapeutic development, with applications in anthrax treatment and cancer therapy.