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Science News for February 1, 2004


Microbial biofilm yields community genomes, metabolic clues

A team of researchers found nearly complete genomes of two organisms in a microbial community from a hot, acidic solution, revealing clues about metabolic activity and speciation. The study sheds light on how bacteria function collectively in acid-adapted environments.

SourceU.S. National Science Foundation·JournalNature·DateFeb 1, 2004

Optic nerve disease may cause sleep disorders

Children with optic nerve disease are up to 20 times more likely to experience excessive daytime sleepiness due to disruptions in their body's internal clock. Researchers found that the loss of a specific type of cell in the retina, which helps regulate light exposure, is directly linked to sleep disturbances.

SourceWashU Medicine·JournalOphthalmology·DateFeb 1, 2004

Pacifying bacteria prevents lethal post-op infections

Researchers have developed a protective coating that prevents deadly post-operative infections from Pseudomonas aeruginosa, a virulent pathogen that kills 100% of untreated mice. The coating, which works by pleasing the bacteria and preventing them from invading the host's bloodstream, has shown promising results in animal studies.

SourceUniversity of Chicago Medical Center·JournalGASTROENTEROLOGY·DateFeb 1, 2004
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New risk factors for retinal disorder identified

A case-control study found associations between CSCR and various systemic conditions, including alcohol, tobacco, and antibiotic use. Eye doctors are advised to discuss these risk factors with patients and take steps to eradicate them.

SourceAmerican Academy of Ophthalmology·JournalOphthalmology·DateFeb 1, 2004

Scientists report first sequencing of environmental genome

Researchers at UC Berkeley have sequenced the genomes of the most abundant members of a community of organisms in an abandoned mine, revealing four previously unknown genomes. This breakthrough in environmental genomics opens up new avenues for understanding microbial interactions and has significant implications for addressing acid mi...

SourceUniversity of California - Berkeley·JournalNature·DateFeb 1, 2004

Activation of receptor ups development of precancerous intestinal polyps

Activation of the PPAR-delta receptor increases development of precancerous intestinal polyps in mice, with larger polyps being more likely to progress to colorectal cancer. Treatment with a specific compound linked to the receptor may accelerate polyp growth through antiapoptotic pathways.

SourceVanderbilt University Medical Center·JournalNature Medicine·DateFeb 1, 2004
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Eye disease may cause sleep disorders

Research suggests eye disease is a risk factor for sleep disorders, particularly in patients with optic nerve disease. The study found that visually impaired subjects with optic nerve disease were nine times more likely to experience pathologic sleepiness than those with normal sight.

SourceAmerican Academy of Ophthalmology·JournalOphthalmology·DateFeb 1, 2004