Researchers developed an algorithm, Q5, using PCA and LDA to differentiate between healthy and diseased blood samples. The algorithm achieved virtually 100% accuracy for ovarian cancer and approximately 95% accuracy for prostate cancer.
A new study suggests that angioplasty can significantly reduce the risk of stroke in patients with clogged brain arteries. The procedure, which uses a tiny balloon to open blocked vessels, has been shown to be more effective than medication alone in improving outcomes.
Researchers at the University of Rhode Island are using virtual reality technology to educate students about the impact of volcanic eruptions on human populations and the environment. The virtual field trip will feature interactive simulations, including footage from a historic eruption and excavated cities like Pompeii.
Researchers at UCI are studying how acupuncture triggers physiological changes in the brain that can reverse illnesses impacting millions of Americans. The study aims to bridge the gap between Western and Eastern medicine, providing a clear medical basis for acupuncture's effects on cardiovascular ailments.
Researchers develop high-throughput method to systematically interrogate gene function using RNA interference, identifying genes involved in cell growth, survival and metabolic processes
Researchers found that agricultural workers who thin orchards have detectable levels of pesticides in their house and vehicle dust, posing a risk to children. Children of thinners were more likely to have detectable pesticide metabolites in their urine, supporting the theory that workers track home pesticides on their clothing and shoes.
HHMI's international programs aim to train and retain young scientists, build centers of excellence, and foster public-private partnerships. The Institute has invested over $100 million to support scientific research and education in 32 countries on six continents.
Researchers found that elevated sFlt-1 levels and low PlGF levels can predict the development of preeclampsia. Women with preeclampsia also have lower VEGF levels, which may contribute to the condition's health problems.
A new study found that nitroglycerin can cause long-term blood vessel damage in rats, leading to increased risk of heart disease and mortality. The drug's ability to dilate blood vessels was found to be short-lived, with mitochondria producing free radicals that can damage heart cells and blood vessel walls.
Experimentally activating individual worker immune responses in Bombus terrestris colonies results in reduced social unity and collective earlier reproduction. This suggests that key elements of immune defense are retained through evolutionary sociality.
Researchers conclude that sexual transmission remains the primary mode of HIV-1 spread in Africa. The authors also acknowledge the need for improved data to identify risks associated with unsafe injections in healthcare settings.
Community invasibility is influenced by resident species composition and community cover. The relationship between richness and invasion dynamics reveals a more complex process than previously thought.
Researchers tested a cooling helmet on patients with severe ischemic stroke, finding that it preferentially cools the brain rapidly and profoundly. The study showed excellent functional recovery in younger patients but only 20% in elderly patients.
Pelagic shark assemblage declines drastically, with oceanic whitetip shark declining by over 99%, yet no conservation attention is given to these species.
Researchers found that the lifetime of water's OH-stretch vibration increases with temperature, weakening hydrogen bonds and allowing molecules to vibrate longer. The study used ultrafast infrared lasers to measure the number of vibrating molecules, revealing a unique property of water.
A new study reveals that genetic traits within plant species play a crucial role in shaping ecosystem responses to global climate change. The research suggests that these variations should be considered when developing habitat conservation plans.
A new study presents promising results for acute stroke treatment using desmoteplase, a genetically engineered blood clot-dissolving protein. MRI techniques also play a crucial role in identifying patients who can benefit from this therapy.
The study found that subtle alterations in the influenza virus's infectivity led to its deadly spread. The researchers determined that a key contributor was the hemagglutinin protein, which allowed the virus to bind to human receptors in an antigenically favorable way.
Rockefeller University scientists have discovered that natural killer cells, a crucial part of the immune system, need to be 'nurtured' before they can effectively destroy tumor and infected cells. This new understanding paves the way for potential changes in bone marrow and stem cell transplant procedures.
The Netherlands has established two new research centers, NIVAREC and PRIOR, to develop and produce flu vaccines and tackle poverty-related infectious diseases. The centers aim to strengthen cooperation between researchers from different institutes and foster knowledge infrastructure in developing countries.
A new method for improving trench profiles in the Bosch process has been developed, allowing for maximum depth-width ratios of over 30. This is achieved through two techniques: adding a third plasma pulse to remove polymer layer and optimizing passivation pulses to prevent polymer deposition.
A new corkscrew-shaped retrieval system has been shown to restore blood flow and reverse paralysis in 61 of 114 patients with ischemic strokes. The device, MERCI Retrieval System, was able to dissolve clots and open blood vessels in patients who were not eligible for standard tPA therapy within three hours.
Researchers have identified elevated levels of soluble fms-like tyrosine kinase 1 (sFlt1) in pregnant women at risk of developing preeclampsia. This finding suggests that sFlt1 may serve as a biomarker for early detection and potentially inform treatment strategies through the administration of drug therapies that neutralize its effects.
Scientists linking rainforest canopy and floor layers examine effects of falling materials on soil processes, decomposition rates, and nutrient availability. The study aims to understand the connection between these factors and global climate change.
Researchers mapped yeast genetic interaction networks, finding that genes interact in 'neighbourhoods' and predicting traits. The study provides new insights into how genes contribute to human disease.
A study of nearly 200 patients found that company doctor adherence to guideline standards reduced absenteeism but decreased patient satisfaction. Factors such as employee pessimism and anxiety disorders also predicted unfavourable outcomes.
Imperial College London researchers have discovered the detailed mechanism of the photosynthetic water-splitting reaction, enabling the potential for industrial-scale hydrogen production. This breakthrough could provide a promising alternative to fossil fuels and address global energy demands.
Research by Martin Muurling found that mice on low-fat diets were more sensitive to insulin, suggesting a low-fat diet may be a more effective remedy for diabetes. The study also showed that consuming fish oil had no positive effects on reduced insulin sensitivity.
The Indiana University-Kenya AIDS program has received an expanded grant, allowing for the treatment of up to 15,000 HIV-infected individuals in rural communities. The new funding will also establish two additional rural programs and support educational initiatives for medical students and providers.
A Stanford study found that Listeria bacteria can survive for long periods outside of its hosts and thrive in the gall bladder, posing a risk of food poisoning. The research suggests that the organ's unique environment makes it an ideal place for the bacteria to grow, highlighting the need for improved hygiene practices.
A study by Northwestern Memorial researchers found that taking baby aspirin or enteric-coated aspirin with Plavix provides a good blood-thinning effect, similar to full adult-dose aspirin. The results suggest that combining these medications can enhance the effectiveness of Plavix in reducing vascular events.
The European organization aims to create a virtual office to facilitate international collaboration and development of new research programs. Researchers will be able to work from various locations throughout Europe.
The researchers solved the structure of the hemagglutinin protein, a crucial component in understanding the 1918 flu outbreak. The study reveals that the virus likely originated from birds and its unique surface proteins made it particularly deadly to young adults.
Researchers found that exposure to thimerosal, a vaccine preservative, can interrupt growth factor signaling and cause adverse effects on methylation reactions. This can lead to disorders such as autism and ADHD in infants and children.
A UK-based study found that individuals who received blood components from donors later diagnosed with vCJD were at increased risk. Researchers also discovered that the BSE agent can be transmitted through intravenous routes, highlighting concerns for possible transfusion cases.
The study reveals a direct activational signal from the synapse to the protein synthesis machinery, enabling neurons to boost protein production rapidly during long-term memory formation and synaptic strengthening. This discovery has significant implications for understanding psychiatric and neurologic diseases, potentially leading to ...
A four-year study published by Ohio State University researchers found that attempting a vaginal birth after C-section (VBAC) is associated with increased risk of maternal morbidity and serious obstetric complications. Despite this, many women continue to opt for VBAC due to the relatively low level of risk involved.
A new study by McGill University researchers has identified phospholipase A2 (cPLA2) as a key enzyme that triggers multiple sclerosis-like disease in an animal model. Treatment with a chemical inhibitor of this enzyme results in a marked reduction in the onset and severity of the disease.
Researchers discovered a possible reason for biodiversity in the Andes by comparing North and South American warming over millennia. The region's gradual warming may explain less extinction and increased susceptibility to global warming.
Researchers have identified the optimal dosage of a bat-derived clot-buster for acute ischemic stroke treatment, finding a dose of 125 micrograms per kilogram to improve neurological function scores. Carotid artery screenings in seniors may also help prevent strokes and save billions of dollars in healthcare costs.
Researchers developed a device called NeuroFlo that increases blood flow to the brain by diverting it from lower extremities. The study tested its safety and effectiveness on 17 patients with ischemic strokes, resulting in improved treatment outcomes for 10 out of 15 conscious patients.
Researchers investigated the effects of caffeine (SRC) and melatonin (Mlt) on jet lag symptoms. The study found that Mlt decreased subjective sleepiness but not objective sleep quality, while SRC reduced sleepiness for a few days with negative effects on recovery sleep. Additional studies are needed to evaluate their full effects.
The Severn Estuary Partnership has received £150,000 funding to improve and develop sustainable access to and around the estuary. The project aims to boost local economies by promoting local produce and enhance nature conservation values.
Researchers develop gene therapy to enhance islet cell function and survival after transplantation. The technique uses a growth factor DNA to induce cell division, improving insulin production and glucose control in rat models. However, standard immunosuppression drug therapy may be harmful, inducing insulin resistance and diabetes.
A team of international researchers, including University of Colorado at Boulder professor Robert Hohlfelder, are searching for the lost fleet of Persian warships in the seas off Greece's northern coast. The team used sonar, a manned submersible submarine and a remotely operated vehicle to locate the site, which was chosen after local ...
Researchers have discovered a link between cystic fibrosis and fatty acid defects, with abnormally high levels of arachidonic acid and low levels of docosahexaenoic acid found in patients. The study suggests that correcting this imbalance may lead to new treatment options for the disease.
Rensselaer Polytechnic Institute researcher is developing a compound to neutralize anthrax toxin, which could be injected into healthy humans as a preventive measure or given to infected individuals as an antidote. The goal is to develop a safe and effective treatment for bioterrorist anthrax attacks.
Researchers at Purdue University developed a miniature device sensitive enough to detect a single virus particle, with applications in environmental health monitoring and homeland security. The device uses a tiny cantilever that vibrates at a specific frequency when a virus particle lands on it, allowing for real-time detection.
Researchers used post-mortem spinal cord tissue to identify a unique gene expression profile in ALS patients, revealing distinct changes underlying the terminal stages of the disease. The study distinguishes between familial and sporadic ALS forms, providing insights into the molecular pathophysiology of neurodegeneration.
A membrane protein called NCX1 plays a crucial role in regulating the frequency and strength of heartbeats by transporting calcium into and out of heart cells. The protein generates electrical currents that contribute to excitation and contraction, making it an important key to understanding cardiac function.
The study found that school sports participation was associated with lower odds of currently smoking cigarettes. However, both chewing tobacco and snuff use were higher among athletic adolescents, indicating that sports do not help keep students away from less incendiary forms of tobacco.
Researchers found that 68% of patients experienced a reduction in pain intensity of greater than 33%, indicating promising relief. The biotoxin blocks slow sodium channel nocicipetive pain fibers in a highly selective way, making it a potential treatment option for cancer pain.
Researchers at Massachusetts General Hospital developed a strain of mice with the c. elegans gene fat-1, which converts omega-6 acids to omega-3s. The transgenic mice produce high levels of omega-3 fatty acids, opening up possibilities for farm animals that naturally produce omega-3 rich food products.
A new procedure, carotid artery angioplasty with stenting (CAS) with distal embolic protection (DEP), has shown zero neurological complications in a study involving 21 patients. The minimally invasive technique adapts techniques used to open heart vessels for brain arteries, significantly reducing risk of stroke and death compared to t...
Researchers found that Dahl R rats exhibit efficient spatial navigation, while Dahl S rats display poor spatial navigation. Analysis of F1 male progeny implicated the X chromosome in the impairment observed in Dahl S rats.
A study found that menthol cigarettes, like Newport, are more attractive to teens, while brand-name cigarette use is concentrated among adolescents. The researchers also discovered that tobacco advertising and promotion budgets increased significantly during the 1990s, contributing to the popularity of certain brands.
The study found that 82% of patients had polycystic ovary syndrome (PCOS), while 6.75% had specific identifiable underlying disorders. Combination hormonal therapy improved most symptoms, including hirsutism, acne, and menstrual dysfunction in 86%, 81%, and 80% of cases respectively.
A study analyzing HMO medical groups found that with efficient care, primary and specialist physicians can serve a large patient population with significantly fewer doctors. The HMOs had about 1 physician for every 650 patients, compared to the current US supply of 1 per 400.
The Acoustical Society of America sponsors two annual awards for outstanding popular works on acoustics. Entries must be published or broadcast between January 1, 2003 and December 31, 2003, and meet criteria for accessibility, relevance, accuracy, and quality. The winners will receive a $1000 prize and an award certificate.
Babytalk plays a crucial role in infants' development of temporal arts, such as literature and music. Depriving babies of poetic elements like alliteration and assonance may hinder their ability to appreciate these arts later on. Researchers argue that babytalk is more significant than previously thought.