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Science News for July 29, 2004


Firefly compound lights up 'protein dance' in living animals

Scientists have developed a technique to detect protein interactions using firefly luciferase. The method was tested on human proteins interacting with the antibiotic rapamycin and showed accuracy and selectivity. The technique also demonstrated its potential in studying other protein pairs linked to cell life cycle regulation.

SourceWashU Medicine·JournalProceedings of the National Academy of Sciences·DateJul 29, 2004

The beak of the squid

A new study reveals that Argonaute2 is the key enzyme responsible for RNAi-mediated messenger RNA cleavage in mammals. The findings suggest that Argonaute2 provides the 'Slicer' activity necessary for siRNA-targeted mRNA cleavage.

SourceCold Spring Harbor Laboratory·JournalScience·DateJul 29, 2004

New hope for the estimated 300,000 Americans co-infected with hepatitis C and HIV

A groundbreaking study by Mount Sinai School of Medicine found that the combination of Pegasysα and Copegus significantly improved treatment response rates for patients co-infected with HCV and HIV. The study showed a sustained virological response rate of 40% among all patients, with even higher efficacy rates for those with genotypes...

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalNew England Journal of Medicine·DateJul 29, 2004

AGU journal highlights - 29 July 2004

Scientists have discovered a unique bi-modal distribution of particles in noctilucent clouds, which may be caused by atmospheric gravity and tidal waves. The San Andreas Fault Observatory project aims to drill into the fault zone to better understand earthquake generation and faulting processes.

SourceAmerican Geophysical Union·JournalGeophysical Research Letters·DateJul 29, 2004

Combining radiation modalities increases

A new study by Mount Sinai School of Medicine researchers found that combining three therapeutic modalities increases the percentage of high-risk patients who are free from recurrence after five years. A three-pronged approach that included brachytherapy, external beam radiation therapy and hormonal therapy produced an 86 percent rate ...

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalInternational Journal of Radiation Oncology*Biology*Physics·DateJul 29, 2004