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Science News for June 13, 2004


Genetic modification in mice lowers cholesterol and homocysteine by half

Researchers genetically modified mice to lack the CT or PEMT pathways, resulting in significant reductions of lipoproteins and homocysteine levels. This suggests pharmacological inhibition of PC manufacture in the liver as a potential approach to lower LDL cholesterol and homocysteine levels.

SourceFederation of American Societies for Experimental Biology·DateJun 13, 2004
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MIT technology jump-starts human embryonic stem cell work

Researchers developed a new technique to test hundreds of different biomaterials at once, improving the growth and differentiation of human embryonic stem cells. This breakthrough allows for more efficient screening of materials and could lead to breakthroughs in tissue engineering and synthetic skin production.

SourceMassachusetts Institute of Technology·JournalNature Biotechnology·DateJun 13, 2004