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Science News for August 11, 2005


Effective Alzheimer treatment: The nose knows

Researchers have developed a new nasal vaccine that decreases Alzheimer's disease (AD) burden in mice by activating microglia to clear beta-amyloid from the brain. The vaccine combines an FDA-approved multiple sclerosis treatment, glatiramer acetate, with a safe and effective nasal adjuvant that has been tested in humans.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateAug 11, 2005

New approach has potential to treat latent HIV infection

A new approach using valproic acid has shown promise in reducing latent HIV infection by 75% in three out of four patients. The researchers suggest that a staged treatment process, starting with standard antiretroviral regimens and then targeting latent viral infection with HDAC inhibitors, could lead to the cure of HIV.

SourceThe Lancet_DELETED·JournalThe Lancet·DateAug 11, 2005

Erotic images, gore cause temporary 'blindness'

Research by Vanderbilt University psychologist David Zald found that emotional images can lead to a phenomenon known as 'emotion-induced blindness,' where individuals fail to detect subsequent visual images. This effect is linked to personality traits, with those scoring high on harm avoidance being more affected.

SourceVanderbilt University·JournalPsychonomic Bulletin & Review·DateAug 11, 2005

Disparate mole-rats

Researchers studied the genetic markers of African mole-rats to understand their complex social behavior. They found that these microsatellites can reveal how traits pass from mother to offspring, potentially explaining why family members support a single mother naked mole-rat.

Long-sought flower-inducing molecule found

A research group has identified a messenger molecule, produced by the FT gene, that induces flower formation in plants. This breakthrough resolves the long-standing mystery of Florigen, a substance thought to control plant flowering, and opens up new possibilities for plant breeding and forestry.

SourceSwedish Research Council·JournalScience·DateAug 11, 2005

UCSD discovery suggests 'protosun' was shining during formation of first matter in solar system

The discovery provides the first conclusive evidence that a 'protosun' played a major role in chemically shaping the solar system by emitting ultraviolet energy. The team used a technique to reveal details about the Earth's early atmosphere from variations in oxygen and sulfur isotopes, indicating the presence of photochemical reactions.

JCI table of contents September 1, 2005

Researchers have solved a 72-year-old mystery surrounding cholesterol production, revealing that Insig proteins play a crucial role in regulating this process. The study found that mice lacking these proteins accumulate excessive cholesterol and fat in the liver, highlighting the importance of Insig in maintaining normal lipid metabolism.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateAug 11, 2005

Key research findings show family therapy is an effective treatment tool for children

A recent study suggests family therapy is an effective treatment tool for children, involving parents in the process can improve outcomes. Family-based treatments like parent management training and behavioral family therapy have shown promise in reducing conduct disorders and substance abuse.

SourceAmerican Medical Association·JournalJournal of the American Academy of Child & Adolescent Psychiatry·DateAug 11, 2005