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Science News for August 14, 2005


Spliceosomal fidelity

The study found that deleting yeast gene ISY1 increases splicing reaction efficiency and improves 3'-splice site accuracy. The researchers believe Isy1 regulates spliceosomal conformation to ensure accurate pre-mRNA splicing.

SourceCold Spring Harbor Laboratory·JournalGenes & Development·DateAug 14, 2005