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Science News for January 4, 2005


Study examines relationship of vitamin A pathway to breast tumor progression

Researchers found that reduced CRBP-I function compromises RAR activity, leading to loss of cell differentiation and tumor progression. The study suggests that somatic CRBP-I loss may contribute to breast cancer development and highlights the need for further research into vitamin A's role in cancer prevention.

SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateJan 4, 2005

Stem cell therapy for ailing hearts

In an animal study, stem cells from human umbilical cord blood significantly reduced the size of heart damage and restored pumping function to near normal after a heart attack. The researchers suggest that these stem cells could be a new treatment for limiting or repairing heart muscle damaged by a heart attack.

SourceUniversity of South Florida (USF Health)·JournalCell Transplantation·DateJan 4, 2005

Environmental tobacco smoke linked to reading, math, logic and reasoning declines in children

A study found that environmental tobacco smoke exposure is linked to significant declines in reading and math scores, as well as logic and reasoning skills in children. The research suggests that even low levels of exposure can have adverse effects on cognitive abilities, with an estimated 33 million US children at risk.

SourceCincinnati Children's Hospital Medical Center·JournalEnvironmental Health Perspectives·DateJan 4, 2005

Homes need more protection against falls

Falls are a leading cause of death from unintentional injury in the US, with 7% of households reporting a fall requiring medical attention. Homeowners can take steps to prevent falls by installing protective devices such as grab bars, handrails, and safety gates.

SourceCenter for Advancing Health·JournalAmerican Journal of Preventive Medicine·DateJan 4, 2005

Ancient DNA helps solve the legend of giant eagles

Researchers at McMaster University have used ancient DNA to study the evolution of the Haast's eagle, a giant bird that once ruled New Zealand. The study found that the species is related to one of the world's smallest eagles, with an estimated common ancestor living less than a million years ago.

SourceMcMaster University·JournalPLOS Biology·DateJan 4, 2005

USC researchers find evidence that progesterone signaling influences ovarian cancer risk

Researchers from USC found evidence that progesterone signaling influences ovarian cancer risk, particularly two haplotypes (4-D and 4-E) that increase risk by almost 3.5-fold in women who carry them. The study's findings suggest that subtle changes in the progesterone receptor gene may decrease its efficiency, leading to ovarian cancer.

SourceUniversity of Southern California·JournalJNCI Journal of the National Cancer Institute·DateJan 4, 2005