Researchers found that women have more global AD pathology due to neurofibrillary tangles and experience clinical symptoms of AD nearly 20 times more often than men. This suggests that Alzheimer's disease is stronger in women, potentially linked to estrogen deficiency or other protective factors.
Researchers have identified three small molecules that can inhibit the enzyme CDK5, which contributes to the development of Alzheimer's disease. The discovery is promising news for the development of new treatments for the disease.
Student researcher Christopher Kovalchick used a low-cost technique to test tiny samples of four metal alloys and found that combining platinum with chromium resulted in the greatest strength. The findings are important because pure platinum is too soft for use in durable jewelry, but adding chromium improves its mechanical properties.
The North Atlantic right whale is facing extinction due to the failure of government protections, with at least 50% of deaths attributed to ship collisions and fishing gear entanglements. The species has seen a significant increase in mortality rates over the past 16 months, including six adult females with near-term fetuses.
Research reveals that high TRAIL-R2 expression in breast cancer patients is associated with poorer survival outcomes. The AQUA TM system was used to analyze tissue microarray specimens and identify correlations between receptor expression levels and clinical variables.
The University of Alaska Fairbanks graduate program's Regional Resilience and Adaptation Program offers potential solutions to modern land-use practices. Students are trained to address issues of regional and global sustainability, recognizing both short- and long-term needs.
Researchers have identified gene mutations that cause life-threatening aortic aneurysms and dissections, providing a new molecular pathway for therapy development and early warning signs. The study found four families with variations in the TGFBR2 gene, which alters protein structure and sends incorrect signals.
Scientists at Galileo Pharmaceuticals confirm a significant link between inflammation and glucose regulation in metabolic disease. The study demonstrates that administration of a proprietary dual 5- and 15-lipoxygenase inhibitor reduces resting glucose levels by approximately 20% without affecting insulin levels.
A four-year study by University of Cincinnati researchers found that living near 'stop and go' traffic increases infant wheezing rates, with African American infants at highest risk. The study suggests that exposure to diesel exhaust particles from 'stop and go' traffic may play a role in developing allergic conditions.