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Science News for March 14, 2005


Reducing hostility in young coronary artery disease patients is important piece of rehabilitation

A study found that young coronary artery disease patients have a high prevalence of hostility symptoms, with improvements in risk factors and quality of life seen after cardiac rehabilitation. The researchers suggest that reducing hostility should be emphasized in rehabilitation following a heart attack to improve long-term prognosis.

SourceMayo Clinic·JournalMayo Clinic Proceedings·DateMar 14, 2005

Inflammatory condition doubles heart attack, stroke risk

A new study published in Heart found that individuals with giant cell arteritis (GCA) have a significantly higher risk of cardiovascular disease compared to healthy adults. The prevalence of GCA is estimated at one per every 500 seniors, and patients with this condition are more than twice as likely to experience heart attacks or strokes.

SourceUniversity of Toronto·JournalHeart·DateMar 14, 2005

Nature helps create religious adults

A study on twin pairs found that environmental influences play a role in shaping religiousness during childhood, but a stronger genetic influence emerges in adulthood. Like other personality traits, adult religiousness is heritable, indicating that an individual's faith can be influenced by their genetic makeup.

SourceBlackwell Publishing Ltd.·JournalJournal of Personality·DateMar 14, 2005

New drug shows promise as powerful anticancer agent

Researchers discover ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, arrests cell division in human cancer cells and inhibits a variety of tumors. Clinical studies are currently underway to determine the best way to utilize this potent anticancer agent.

SourceCell Press·JournalCancer Cell·DateMar 14, 2005

Gray wolves maintain the food chain in winter

A new study from PLOS Biology shows that reintroduced gray wolves in Yellowstone Park provide a crucial safety net for scavengers during climate change. Wolf kills temper the devastating effects of climate-related carrion shortages on scavengers.

SourcePLOS·JournalPLOS Biology·DateMar 14, 2005

Heart repair gets new muscle

Researchers have discovered that skeletal precursors of cardiomyocytes (Spoc cells) can transform into beating cardiac muscle cells, offering hope for developing cell-based treatments for heart disease. These cells were isolated from adult mice and showed spontaneous rhythmic beating and expressed cardiac markers.

SourcePLOS·JournalPLOS Biology·DateMar 14, 2005

Orchestra pit no danger to hearing

A study by University of Toronto researchers found that orchestra musicians are not at risk of hearing loss in the pit, despite playing for long hours. However, individual practice and measures such as earplugs can still help protect their hearing.

SourceUniversity of Toronto·JournalApplied Acoustics·DateMar 14, 2005

Using molecular technique, researcher identify hospital pool bacterial pathogen

A recent study by Washington University researchers used a molecular survey to detect Mycobacterium avium in the lungs of nine lifeguards who developed hypersensitivity pneumonitis after exposure to pool water. The bacterium, known for its resistance to disinfection, was found at high levels in air samples taken near the pool.

SourceWashington University in St. Louis·JournalProceedings of the National Academy of Sciences·DateMar 14, 2005

Mountain life spells longer life

A 15-year study in rural Greece found that living in a mountainous area was associated with lower death rates and healthier heart profiles compared to lowland areas. Higher blood lipids and blood pressure were linked to increased risk, but other protective factors may be at play.

SourceBMJ Specialty Journals·JournalJournal of Epidemiology and Community Health·DateMar 14, 2005

Neurobehavioral function during coma, stroke rehabilitation effective for elderly

A two-part study examines the effectiveness of neurobehavioral function assessments during coma and stroke rehabilitation for elderly individuals. The Disorders of Consciousness Scale reliably predicts recovery of consciousness, while tracking individual neurobehavioral recovery patterns improves medical and rehabilitation management.

SourceVeterans Affairs Research Communications·JournalThe Journal of Rehabilitation Research and Development·DateMar 14, 2005

HIV-1 spread through six transmission lines in the UK

A collaborative study by UCL scientists found that HIV-1 subtype B spread through at least six separate transmission chains in the UK, contradicting the prevailing belief of a single initial entry. The study suggests changes in sexual behavior and lack of impact from antiretroviral therapy may have slowed the epidemic growth.

SourceUniversity College London·JournalProceedings of the National Academy of Sciences·DateMar 14, 2005

Genetics important in age-related macular degeneration

A twin study found that genetic factors contribute substantially to the development of AMD, accounting for 46-71% of disease severity variation. Environmental factors also play a role, with unique environment contributing 19-37% and shared environment 28-64% to AMD grade and specific macular measures.

SourceJAMA Network·JournalArchives of Ophthalmology·DateMar 14, 2005

Researchers rein in regulatory RNAs

The study reveals that antisense transcripts (SATs) are widely expressed in various mouse tissues and cell cultures, exhibiting tissue-specific expression patterns. SATs tend to be poly(A)-negative and enriched in the nucleus, suggesting a functional role in gene regulation.

SourceCold Spring Harbor Laboratory·JournalGenome Research·DateMar 14, 2005

Short-term effects of spit tobacco suggest long-term health risks

A Mayo Clinic study found that spit tobacco use can cause dramatic increases in heart rate and blood pressure, blunting the body's natural protective mechanisms. This raises concerns for both short-term users and individuals with established heart disease, suggesting a link to long-term cardiovascular risks.

SourceMayo Clinic·JournalJournal of the American College of Cardiology·DateMar 14, 2005