A global team of RNA scientists will develop a common vocabulary and scientific concepts to facilitate communication and knowledge-sharing. The project aims to integrate RNA sequence and 3D structure databases to advance understanding of cellular growth and development, key to curing hereditary diseases.
Researchers at Northwestern University have developed a new solid oxide fuel cell that converts liquid transportation fuels into hydrogen, offering a more efficient and cost-effective alternative to current technologies. The cells could lead to widespread adoption of hydrogen power in applications such as cars, trucks, and homes.
A study published in Science found that charcoal use in Africa contributes to premature deaths and greenhouse gas emissions. The authors suggest transitioning from biomass fuels to cleaner alternatives could prevent millions of premature deaths.
A study by Harvard researchers suggests promoting cleaner charcoal production can prevent up to 2.8 million deaths and reduce greenhouse gas emissions by 45-66%. Transitioning from biomass fuels to petroleum-based fossil fuels offers the biggest health benefits, but is unlikely due to economic and infrastructure constraints.
A study of 12,110 men and women aged 16-44 in Great Britain found significant variations in sexual behavior and sexually transmitted infection (STI) rates among white, black Caribbean, black African, Indian, and Pakistani groups. Indian and Pakistani individuals reported fewer STIs and more consensual relationships.
Researchers at UCSD School of Medicine have discovered a natural tumor suppressor called PHLPP, which can be turned on in certain cancer cells to prevent tumor formation. By deleting a phosphate molecule from the Akt protein, PHLPP terminates cell-growth signaling and promotes programmed cell death.
Researchers discovered that blue light can rapidly kill certain oral bacteria associated with periodontitis, and may restore a healthy bacterial balance in the mouth. A handheld device using this technology is being developed to combat periodontal disease.
Scientists have found magnetic fluctuations responsible for superconductivity in a compound called plutonium-cobalt-pentagallium (PuCoGa5). This 'unconventional superconductivity' could lead to a new class of superconducting materials and the synthesis of room-temperature superconductors.
Researchers at Boston University have developed a new technique to identify plant species used in ancient textile dyes. This method has led to the discovery of a previously unknown dye component in 1,000-year-old mummies in Peru.
A study suggests that community acquired MRSA has evolved from a 1950s pandemic-causing strain, developing resistance to treatment by powerful antibiotics. The new strain shares the same highly-virulent toxin and poses a serious public health challenge.
A new study published in The Lancet identified a biomarker NGAL that can detect kidney failure hours after cardiac surgery, offering hope for earlier diagnosis and treatment. The research found high concentrations of NGAL in urine and blood samples within two hours of surgery, indicating the presence of kidney failure.
A new study using hyperscanning technology measures the brain's response to trust decisions, revealing a shift in timing as interactions progress. The technique may provide valuable insights into conditions such as autism and schizophrenia.
A study shows that lidocaine patch 5% and celecoxib achieved significant reductions in pain intensity, with 62% of patients in the celecoxib group experiencing a 30% or greater improvement. The findings offer hope for OA patients seeking alternative pain relief options.
A new global risk analysis reveals that approximately 20% of the Earth's land surface is exposed to at least one natural hazard, affecting over half the world's population. The study categorizes regions by their level of exposure to multiple hazards, highlighting countries with high mortality risks from two or more hazards.
Scientists have developed a new technique to track molecular energy transfer in photosynthesis, revealing distinct energy pathways and quantum mechanical effects. This breakthrough may lead to more efficient artificial photosynthesis systems and sustainable energy sources.
Researchers discover that MT1-MMP controls blood vessel response to PDGF-ß signaling, essential for normal vessel formation. MT1-MMP-null mice exhibit severely compromised vascular architecture, suggesting potential therapeutic targets for controlling tumor growth and metastasis.
Researchers at Queen's University discovered that a combination of gabapentin and morphine provides better pain relief for patients with diabetic neuropathy and postherpetic neuralgia, while also minimizing side effects. The study used a clinical trial to compare the treatment to individual medications and a placebo.
Researchers from U of T mapped the role of Epstein-Barr virus in cancer, finding that EBNA1 protein disrupts natural cell growth regulation by binding to USP7, increasing cancer risk. This study provides a structural explanation for how EBNA1 impacts cell growth, paving the way for developing better methods to combat viruses like EBV.
A new study by UMaine researchers found that consistency in sleeping arrangements is crucial for infants' nighttime sleep. The study suggests that changing sleeping arrangements can be disruptive to sleep and contribute to night-time anxiety in infants.
Researchers have discovered a promising new treatment for chronic Chagas disease, with one compound showing significantly greater effectiveness than current standard care. TAK-187 prevents the parasite from producing essential ergosterol, reducing cardiac and skeletal damage without toxic side effects.
Phytome is a comprehensive database of genetic data on 39 plant species, including rice, wheat, and potatoes. The platform enables researchers to analyze complex questions about gene function and comparison across different species.
Researchers have identified a novel protein, MKRN1, that regulates telomerase activity and maintains cellular telomere lengths. Increasing MKRN1 levels in cells promotes the degradation of telomerase enzyme hTERT, leading to decreased telomerase activity and shorter telomeres.
A new University of Southern California study finds that a tsunami in the region could cause significant economic losses, with Long Beach suffering an estimated $3.6 billion in damage. The study estimates potential damage ranging from $7 billion to $42 billion, with effects felt across Southern California.
Scientists find that a region near the head of the ataxin-3 protein counterbalances toxicity caused by excessive polyglutamine repeats, potentially offering a therapeutic solution for Machado-Joseph disease and related disorders. The study suggests that removing or altering this region can accelerate disease progression.
A head-to-head study comparing Lidoderm patches and Celebrex found that Lidoderm alleviated knee pain in 54% of patients, while Celebrex showed similar results in 62%. The study's findings are promising for further research into Lidoderm's potential as an osteoarthritis treatment.
Critics argue that outsourcing of hospital cleaning staff may contribute to increased deaths from MRSA, but hand hygiene and glove use are key to controlling transmission. The Lancet suggests that UK policies focus on the wrong issue, prioritizing housekeeping programmes over essential infection control practices.
A new protocol provides incentives for federal agencies to trust each other and share accurate, complete information in a timely manner. This increases the efficiency of information sharing and builds trust between organizations.
A five-year study in Mexico found that the Directly Observed Therapy (DOTS) strategy significantly reduced drug-resistant TB transmission. The results showed a decline from 22% to 7.8% of new patients carrying drug-resistant strains, with no cases of multiple-drug resistance.
Researchers found two cases of severe anxiety and impaired psychomotor functions in male subjects who received oral cannabis, despite low blood concentrations. The study suggests that ingesting THC may produce potent metabolites that induce psychotic effects, contradicting previous expectations of safety with low doses.
Researchers have found a novel biomarker, neutrophil gelatinase-associated lipocalin (NGAL), that can detect kidney failure in children after cardiac surgery in as little as two hours. This early diagnosis enables timely administration of effective therapeutic measures to prevent further complications.
A new study reveals that adult non-biting midges serve as vectors for the spread of cholera. The researchers found that these insects can carry and transmit the bacteria across continents through wind currents, air travel, and human migration.
A study in Southern Mexico found that implementing DOTS (short-course chemotherapy) significantly reduced the incidence of drug-resistant tuberculosis, from 9.4 to 1.5 cases per 100,000 people between 1996 and 2000. The strategy also improved treatment outcomes for patients with drug-resistant TB.
Drezek has been recognized by the Beckman Foundation for her research on novel optical molecular imaging technologies for early cancer detection. Her award includes a three-year $264,000 grant to develop and refine this technology.
ParksWatch's investigation reveals widespread, unregulated mahogany logging within the remote Alto Purús National Park in the Peruvian Amazon. The report exposes the illicit trade of this valuable timber species, which threatens its survival and ecosystem health.
A recent UCSF study has identified a genetic mutation in the casein kinase1 delta (CK1 delta) gene that is associated with familial advanced sleep phase syndrome (FASPS), a rare sleep disorder. The research, published in Nature, also suggests that circadian rhythm variants may contribute to psychiatric disorders such as depression.
Researchers at Cincinnati Children's Hospital Medical Center discovered that blocking cyclophilin D protects the heart from injury due to loss of blood flow. A class of drugs already exists that blocks cyclophilin D and has been shown to protect against stroke in animal models.
The children and grandchildren of early immigrants played a significant role in shaping American society through their support for New Deal programs and Great Society reforms. The present share of Americans with recent family roots in other cultures is closer to 20-25%, reflecting the nation's increasing diversity.
A study by Ohio State University researchers found that viewing past events from a third-person perspective emphasizes the meaning of an event and accentuates changes. This technique can help individuals see positive progress and improve behavior, leading to greater satisfaction with their efforts.
A genetic mutation in a previously unknown circadian rhythm gene causes Familial Advanced Sleep Phase Syndrome (FASPS), shifting people's sleep times and daily schedules. Affected individuals live normal lives, but some struggle with being out of sync with the world.
Research analyzed emergency medical treatment for assaults during international rugby and football matches in Cardiff. The results showed a significant increase in assault cases on match days, with the highest rates observed when Wales won its matches.
A leading ethicist argues that taking part in medical research is a moral duty for the public good. He suggests changing the Declaration of Helsinki to justify compulsion in certain circumstances, citing examples like vaccination and jury service.
The first UK cases of Lymphogranuloma venereum (LGV) have been reported in gay men, mostly from London. The disease is caused by a particularly invasive strain of Chlamydia trachomatis and can lead to chronic infection with fistulas and problems with the lymphatic system.
Researchers found that clear display conditions improve human vision learning, allowing for optimal training of individuals with lazy eye or related disorders. The study suggests that each eye should be trained separately in clear displays for maximum benefit.
A study found that violent crime surges in low-crime areas hurt business growth and employment in retail and service businesses, while having little effect on businesses in high-crime neighborhoods. The fear of crime affects customer choices and employee willingness to work in neighborhoods with increased homicide rates.
A University of Minnesota researcher reports 14 cases of NAION linked to Viagra use. Patients had arteriosclerotic risk factors and low cup to disk ratios, increasing risk of permanent vision loss.
The European Cancer Research Funding Survey reveals Europe spends seven times less on cancer research per person than the USA, leading to inadequate prevention and clinical research funding. The survey calls for increased funding to translate cancer research into patient benefit and prevent brain drain in clinicians and scientists.
A new study found that aspirin is as effective as warfarin in treating blocked brain arteries but has a significantly lower risk of major hemorrhage and death. The study, which involved over 500 patients, suggests that aspirin could be a safer alternative to warfarin for those with intracranial stenosis.
Researchers found changes in prefrontal brain function during a placebo lead-in predicted adverse effects in subjects who received an antidepressant. This study's unique design uses quantitative electroencephalography (QEEG) imaging technique cordance to identify individuals at risk of side effects.
Scientists have identified a potential new treatment for structural heart disease by blocking the activity of a protein called CaM kinase. The findings suggest that inhibiting this protein may prevent or reduce symptoms associated with structural heart disease, including electrical instability and mechanical dysfunction.
Researchers at the University of Washington have identified separate genes that influence decoding speed and accuracy in individuals with dyslexia. The study, published in Molecular Psychiatry, found that genetic influences on speed and accuracy are distinct, with chromosome 2 playing a significant role.
Researchers found that treating sleep disturbances in epileptic children improves their epilepsy, daytime behavior, concentration, and learning capacity. The study suggests that addressing underlying sleep disorders can have a significant impact on children's cognitive abilities.
Jim Hutchison's new patent may lead to the development of ultrasmall transistors that operate efficiently at room temperature, revolutionizing electronics and optics. The nanoscale transistors are composed of nanoparticle building blocks and function based on a mix of classical and quantum mechanical properties.
Purpura fulminans is a newly emerging deadly disease characterized by skin lesions and tissue damage. Researchers at the University of Minnesota have identified three recommended treatments for purpura fulminans, including antibiotic therapy against Neisseria meningitidis and methicillin-resistant S. aureus.
A study of 127 young women found that those who developed physically later were more likely to contract HPV, chlamydia, and bacterial vaginosis. Younger, more sexually mature teens had lower infection rates due to higher estrogen levels.
A recent study by Emory University Health Sciences Center found that patients newly diagnosed with HIV are more likely to enter outpatient care with case management. The study showed that 78% of patients with case management visited an HIV clinician at least once within 6 months, compared to 60% in the standard-of-care group.
Researchers found that urine's limited niacin triggers Candida glabrata's adhesion-promoting genes, allowing it to stick to host cells. The study provides insights into the mechanism of C. glabrata's adherence to mucosal tissues and blood vessels.
Researchers have identified a missing enzyme in M. tuberculosis that plays a crucial role in the bacterium's ability to acquire iron through mycobactin synthesis. This discovery highlights the importance of understanding the iron scavenging pathway in TB and provides new avenues for developing effective anti-TB drugs.
A new study found that Geodon significantly reduces time in restraints for patients experiencing severe agitation, regardless of the cause. The medication was also shown to be effective in treating agitation caused by alcohol and drug overdoses.
Researchers aim to develop drugs that block anthrax spore germination by understanding the role of Coenzyme A in regulating the process. By studying three-dimensional protein structures, they hope to identify vulnerabilities for new therapeutic agents.
The study recommends routine voluntary testing to diagnose undiagnosed HIV cases, especially among high-risk groups. This approach aims to provide counseling on prevention and treatment options.