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Science News Archive May 2005


Page 1 of 16

Navigating an integrated yeast network

Lan Zhang et al. integrated five biological relationships to discover recurring patterns and themes, highlighting previously unknown relationships between functional modules. Their approach can predict interactions and gene functions, offering a basis for detailed network reconstruction and understanding biological networks.

SourceBMC (BioMed Central)·JournalJournal of Biology·DateMay 31, 2005

Shorter course of radiotherapy effective for palliation of painful bone metastases

A randomized trial of 900 patients with breast or prostate cancer found that a shorter course of radiation therapy was as effective as the standard treatment in providing pain relief. The study also showed less acute toxicity and re-treatment rates in patients who received a single dose of 8 Gy radiation.

SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateMay 31, 2005

miRNA profiling

The miRNA profiling technique is widely used in cancer research to identify and quantify microRNAs in tumor tissues. Researchers have found that specific miRNA patterns are associated with different types of cancers, leading to potential biomarkers for diagnosis and treatment.

SourceCold Spring Harbor Laboratory·JournalGenes & Development·DateMay 31, 2005

Cancer patients have increased risk of cognitive dysfunction, study finds

A study by Beth E. Meyerowitz and colleagues found that cancer survivors are twice as likely to experience cognitive deficits, including dementia, compared to their cancer-free twins. The authors suggest that cancer treatments may lower survivors' cognitive reserve, leading to increased risk of long-term cognitive dysfunction.

SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateMay 31, 2005

Non-dieters more successful at boosting health than dieters, study finds

A new study by UC Davis researchers suggests that learning to recognize and follow internal hunger cues can significantly improve overall health regardless of weight loss. Non-dieters who adopted the Health at Every Size approach showed significant improvements in metabolic and psychological health, including lower cholesterol levels a...

SourceUniversity of California - Davis·JournalJournal of the American Dietetic Association·DateMay 31, 2005

Mayo Clinic Proceedings studies risk factors for blood clots

Research from Mayo Clinic Proceedings reveals that patients traveling long distances prior to surgery are at increased risk of postoperative blood clots, which can be life-threatening. The study also found a threshold for anesthesia duration that increases the risk of blood clots in veins after surgery.

SourceMayo Clinic·JournalMayo Clinic Proceedings·DateMay 31, 2005

Other highlights in the June 1 JNCI

Research on the ATM gene suggests that women carrying one mutated copy are twice as likely to develop breast cancer, with a lifetime risk of one in six compared to one in 11 in the general population. Meanwhile, a new study on ursodeoxycholic acid treatment found a 39% reduction in colorectal adenoma recurrence among patients who recei...

SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateMay 31, 2005

Richer nations at more risk of schizophrenia

A comprehensive survey of schizophrenia rates around the globe debunks a popular textbook definition that the disorder affects 10 in every 1000 people. The study reveals the incidence and prevalence of schizophrenia varies greatly between regions, with poorer countries having more women affected than men.

SourceResearch Australia·JournalPLOS Medicine·DateMay 31, 2005

Tort reform associated with increase in physician supply

A study found that adopting direct malpractice reforms led to a significant increase in the overall supply of physicians. The researchers discovered that these reforms had a larger effect on nongroup vs. group physicians, specialties with high malpractice insurance premiums, and states with high levels of managed care.

SourceJAMA Network·JournalJAMA·DateMay 31, 2005

Messenger peeks at Earth

MESSENGER successfully tested its main camera by snapping distant approach shots of Earth and the Moon. The images show bands of clouds between North and South America on Earth's sunlit side, providing valuable data for planetary exploration.

New complicated grief treatment holds promise for millions, Pitt researchers report

A new treatment approach for complicated grief, developed by University of Pittsburgh researchers, has shown significant promise in improving symptoms and reducing emotional pain. The treatment, which combines elements of interpersonal psychotherapy with a unique two-pronged approach, was found to be more effective than a comparison th...

Sickle cell and protection against malaria

Researchers have found that carrying the sickle cell gene provides partial protection against malaria, increasing to 60% in childhood before declining. The study suggests an immune component to this protection and may offer insights into developing an effective vaccine.

SourcePLOS·JournalPLOS Medicine·DateMay 30, 2005

Longevity controlled by calorie quality, not quantity

Researchers found that reducing yeast in flies' diet increased life span by over 60%, suggesting protein or fat plays a greater role in longevity than sugar. The study's findings challenge the conventional wisdom that eating less promotes longevity and provide insight into the effects of different nutrients on life span.

SourcePLOS·JournalPLOS Medicine·DateMay 30, 2005

In those genetically predisposed, 'developmental reprogramming' could explain cancer risk

A study published in PNAS found that prenatal exposure to diethylstilbestrol (DES) can permanently alter tissue in rats, making them more susceptible to hormone-dependent tumors. The researchers believe this phenomenon could explain why some people with inherited tumor suppressor gene defects develop cancer while others do not.

SourceUniversity of Texas M. D. Anderson Cancer Center·JournalProceedings of the National Academy of Sciences·DateMay 30, 2005

Medical whistleblowers speak out

Five high-profile medical whistleblowers share their accounts of practices in medicine and research that risk public health and safety. They reveal the 'pharma-FDA complex' may compromise drug development, prescribing, and safety monitoring, leading to potential disasters like Vioxx.

SourcePLOS·JournalPLOS Medicine·DateMay 27, 2005