The Research on Adverse Drug Events and Reports (RADAR) Project has identified serious adverse drug reactions with 14 commonly prescribed drugs and cardiac stents, affecting almost 1,700 patients. RADAR reviews have been published in leading medical journals and have helped save hundreds to thousands of patient lives.
A new technique using a femtosecond-pulsed laser can create highly precise incisions, leading to faster healing and stronger transplants. Clinical trials are expected to begin this summer, offering hope for patients with corneal disorders.
A study published in JAMA found that black women had a significantly lower risk of fractures than white women at every level of bone mineral density. Despite this, researchers emphasize the importance of considering individual factors such as body weight and other risk factors when assessing fracture risk.
A study published in JAMA Network found that men with low-grade prostate cancer have a small risk of progression even after 20 years of observation or androgen withdrawal therapy. The results suggest that localized, low-grade prostate cancer patients may not require aggressive treatment.
Researchers studied isotope anomalies in rocks, ice cores, and atmospheric samples to understand the rise of oxygen in the atmosphere. They found that ultraviolet light from the Sun drove atmospheric evolution, leading to the formation of ozone that shields life on Earth.
Boostrix is approved by the FDA for use in US adolescents against pertussis, with reported cases rising nearly 20-fold since 1976. Experts estimate the true incidence of the disease may be greater than one million cases per year, particularly among teens.
Researchers found that advanced NSCLC patients with high EGFR gene copy number, protein expression, or mutations respond better to gefitinib. High EGFR gene copy number is associated with prolonged survival and disease control.
Researchers found that low-dose MDCT can provide similar diagnostic image quality to standard-dose CT scans while reducing radiation doses by up to 10 times. The study suggests low-dose MDCT is a better option for evaluating sinus disease in children due to its improved accuracy and reduced need for sedation.
A new study found that increasing Pap screening adherence and improving its accuracy could reduce the incidence of invasive cervical cancer among women with access to screening. The study also identified factors associated with screening failure, including lack of Pap testing and unrelated outpatient visits.
Researchers at Rutgers are studying the effects of plant extracts on metabolic syndrome, a condition characterized by obesity, hypertension, and high insulin levels. The center aims to identify chemical compounds with therapeutic potential and develop new treatments for this growing public health concern.
Researchers found that leptin replacement treatment altered brain structure and reduced cravings for people with an obesity gene. The study suggests new potential treatments for weight-related issues.
MicroRNAs play a crucial role in regulating plant development by controlling gene expression related to the auxin response pathway. Studies show that microRNA-mediated regulation of genes like ARF17 and NAC1 is essential for normal plant growth, affecting root and shoot development.
NJIT digital poetry expert Dr. Funkhouser will teach a course on hypermedia writing and lead a creative multimedia workshop in Malaysia. He aims to integrate disparate forms of expression into useful hypermedia documents by leveraging database programming.
Infants of mothers with posttraumatic stress syndrome disorder (PTSD) symptoms after 9/11 have significantly lower cortisol levels compared to those born to mothers without the condition. This effect is observed both in utero and after birth, suggesting a potential biological risk factor for PTSD.
Ron Davidson, a professor at Princeton University, has received the 2005 Particle Accelerator Science and Technology Award for his contributions to the theory of charged particle beams. His work has applications in particle physics, nuclear physics, ion-beam-driven fusion, high energy density physics, and cancer therapy.
Researchers found that sirolimus-eluting stents significantly reduced the need for target-vessel revascularization (TVR) and cumulative incidence of death, reinfarction, stroke, or TVR compared to bare-metal stents. The STRATEGY trial showed a reduction in heart attack risk with tirofiban plus sirolimus-eluting stenting.
An observational study found that drug-releasing stents have a higher incidence of stent thrombosis beyond 30 days compared to clinical trials. The study identified premature antiplatelet therapy discontinuation, kidney failure, and diabetes as independent predictors of stent thrombosis.
Proconsul, a 18 million-year-old creature, holds the key to human and ape origins. The book provides an insider's view on fossil discovery and interpretation, exploring Proconsul's anatomy, diet, and habits.
Researchers from Thomas Jefferson University have successfully created plant factories that produce antibodies against tumor cells, offering a potential alternative to expensive and traditional methods. The plant-made antibodies show similar effectiveness in inhibiting tumor growth as mammalian-made monoclonal antibodies.
A study published in the American Journal of Roentgenology found that MDCT is highly accurate in diagnosing coronary artery disease in patients with little to moderate calcium buildup. However, its accuracy drops significantly in cases with severe calcification, emphasizing the need for conventional angiography in such cases.
The Sapling Foundation grant will support OneWorld Health's efforts to develop new medicines for infectious diseases affecting the developing world. The Institute develops affordable treatments for diseases like visceral leishmaniasis, malaria, and diarrhea, with a focus on pre-clinical studies and clinical trials.
A new study found that spacing out insulin given by an insulin pump in two doses, one over eight hours, can keep glucose levels more favorable than a single dose or double dose taken over shorter periods. This method showed improved blood glucose control after a pizza meal without causing hypoglycemic events.
The Field Museum is preserving the audio descriptions of its prized Pacific collection, recorded on sonobands in the 1950s and 60s. The project involves converting the recordings to a digital format, which has proven challenging due to the deterioration of the sonoband medium over time.
A telephone survey found that celebrity endorsements increased awareness and likelihood of certain cancer screenings, including mammography, PSA testing, and sigmoidoscopy. The study highlights the complex decision-making process around cancer screening, suggesting a need for celebrities to inform rather than persuade the public.
Researchers have developed a new tool that allows them to visualize cells in real-time, revealing details about their movement and behavior. The technique, called two-photon laser-scanning microscopy, has provided insights into the goal-oriented migration of activated T cells and the random wanderings of immature T cells.
CONRAD will conduct two Phase III clinical trials in India and four African countries to test a vaginal microbicide candidate, Ushercell, developed by CONRAD in collaboration with Polydex Pharmaceuticals. The goal is to determine its effectiveness in preventing HIV transmission.
A randomized controlled trial of 302 patients with migraines found that acupuncture and sham acupuncture resulted in similar reductions in headache frequency. While acupuncture was associated with a reduction in migraine headaches compared to no treatment, the effects were comparable to those observed with sham acupuncture.