Researchers have engineered mice to respond to a therapy that lowers beta amyloid production, which forms senile plaques in the brain. Early treatment may be crucial in preventing plaque growth and improving outcomes for patients with Alzheimer's disease.
Researchers reject competitive accretion model, which predicts stars form through gas accretion, in favor of gravitational collapse and fragmentation theory. The new model shows turbulence hinders accretion, resulting in stable core mass, contradicting observations of brown dwarfs with planetary disks.
A team of scientists has successfully created a new material that induces magnetic vibrations at visible light frequencies, allowing for the creation of ultra-small optical lenses and miniature lasers. This breakthrough could lead to significant advancements in optics, optoelectronics, and biosensing.
Professor Larry Milstein has been recognized with an endowed chair for his contributions to wireless communication, particularly CDMA and interference suppressing receivers. His research focuses on ultra wideband communications, MIMO systems, and orthogonal frequency division modulation.
A study published in The New England Journal of Medicine found that combining lifestyle modification with the weight loss medication sibutramine resulted in significantly greater weight loss among obese adults compared to using medication alone. Participants who kept daily food and physical activity records showed the most significant ...
Dr. Warner, a renowned expert in aging research, is honored with the prestigious award for his contributions to promoting basic research and bridging the gap between science and practice. He will present a keynote lecture at the GSA's Annual Scientific Meeting.
Researchers found a twofold increase in adolescent depression visits between 1995 and 2002, with medication use rising from 47% to 52% and psychotherapy dropping from 83% to 68%. SSRIs accounted for 76% of prescribed antidepressants during this period.
Research reveals a likely connection between early-life stress and teenage mental health problems, including behavioral and emotional disorders. Monkeys studied showed similar responses to early-life stresses as human children, providing a clearer developmental picture.
Brown Wilson, president of the Jessie F. Richardson Foundation, will receive the award for her work in developing assisted living projects serving diverse populations. Her innovative programs demonstrate excellence in translating research into practical application and policy.
A one-year study found that combining weight loss medication with a comprehensive program of lifestyle modification yields twice the weight loss compared to using either approach alone. The study showed participants who received combined therapy lost significantly more weight than those in other groups.
Climate models project significant changes in global water availability by 2050, with varying trends across regions. The study highlights the complex relationship between climate and water resources, noting that warmer temperatures can lead to both increased and decreased water supply in different parts of the world.
A study by Swedish researchers found that nearly all women wanted children, but only 3% preferred to delay their last birth until between 35 and 39. Many women also delayed their first child until their 40s. The study highlights the need for increased awareness of age-related decline in female fertility.
Harrington's research has had a national impact on long-term care policies, informing the U.S. General Accounting Office and Senate Special Committee on Aging investigations. Her work led to budget legislation increasing minimum staffing standards and salaries for California nursing home staff in 1999.
A study found that lifetime illegal drug use accounts for nearly a third of patients visiting an inner city hospital emergency department. Recently used drugs significantly increase the risk of requiring emergency care, with possible 1 million ED attendances and 40,000 acute admissions annually in England.
UC Davis researchers have discovered a genetic switch, Ku86, involved in cells' response to radiation therapy. The switch, when turned off, enhances the effectiveness of radiation therapy with less toxicity than current radiosensitizing drugs.
A USC-led study found that higher ozone levels during pregnancy are associated with lower birth weight and increased risk of intra uterine growth retardation. The researchers monitored ozone and carbon monoxide levels in Southern California communities and analyzed birth records from over 3,900 children.
Two studies on obesity pharmacotherapy were published in the New England Journal of Medicine, exploring the efficacy of lifestyle modification and pharmacological interventions. Dr. Susan Yanovski, director of the NIDDK's Obesity and Eating Disorders Program, is available to comment on these findings.
Advanced imaging techniques allow researchers to visualize and analyze the protein-conducting channel with unprecedented detail. The study reveals new insights into the structure and function of this complex biological system.
Dr Cleaveland's project seeks to eliminate rabies by targeting its primary source: dogs. The research also sheds light on the role of wildlife in transmitting diseases between species.
A study found that decaffeinated coffee consumption increased levels of fatty acids and Apolipoprotein B (ApoB) in the blood after three months, potentially promoting heart disease risk. In contrast, caffeinated coffee had no significant effects on these markers.
Masternak will receive the award for best paper published in Journal of Gerontology: Biological Sciences for 2005. The presentation will take place on November 20th at 12:15 p.m. at the Orlando World Center Marriott Resort.
Researchers have obtained the crystal structure of phytochrome, a protein that regulates plant growth and development in response to light. The discovery may lead to precise control over flowering events and improved crop yields.
Despite updated guidelines and advances in treatment, a quarter of COPD patients hospitalized with an exacerbation will die within a year. Experts recommend prioritizing prevention of exacerbations and slowing down disease progression over symptomatic relief as the primary goal in COPD management.
CERN has been awarded a high-performance computing prize at the Supercomputing 2005 conference. The recognition is due to CERN's pioneering work on the LHC Computing Grid and its collaborative efforts with industrial partners in developing grid technology.
Dr. Cavanagh's donation honors the contributions of Paul M. Bass and W. Plack Carr Jr., who made his past achievements possible. Dr. Cavanagh's research involves developing new contact lenses with improved oxygen flow, impacting millions worldwide.
Researchers at Princeton University developed an algorithm to optimally assign funding proposals to reviewers, resolving a long-standing issue for the National Science Foundation. The solution has broad applications in scheduling interns, deploying combat units, and assigning teachers to classes.
Researchers have found that valproic acid reduces skin disease and kidney disease in mice with lupus, a condition affecting over 1 million Americans. The drug has been shown to slow the progression of kidney problems, inflammation, and other symptoms.
Aronow, a leading geriatric cardiologist, receives the 2005 Freeman Award for his work in gerontology and long-term care. The award recognizes his contributions to the field of aging and gerontological research.
Dr. Hobbs and Dr. Grundy, two UT Southwestern researchers, have been recognized by the American Heart Association as Distinguished Scientists for their contributions to cardiovascular research and treatment. The recognition acknowledges their lifelong dedication to advancing our understanding of heart disease and stroke.
A synthesis report reveals climate change's growing health impacts vary by region, with coastlines and sub-Saharan Africa particularly at risk. The report highlights the need for global leadership in reducing greenhouse gas emissions and sustainable energy policies.
A new 12-point plan provides guidance on conducting email-based health research, emphasizing the need for informed consent, identity protection, and confidentiality safeguards. The plan aims to maximize technical knowledge and secure the research process.
A study by Barkin and colleagues found that when pediatricians discuss seven key health topics, parents are more likely to remember the advice. Discussing too many topics leads to decreased parental recall. The research aims to improve family education and patient outcomes in pediatric care.
A study of 553 patients found that those with a history of heart problems were more likely to receive cholesterol-lowering drugs, while those without a history received less treatment. The lack of aggressive treatment for peripheral artery disease (PAD) has significant implications for patient outcomes.
A new study from Johns Hopkins Medicine finds that alagebrium reduces stiffening in arteries by 37% and improves endothelial function by 102%. The drug works by breaking down advanced glycation endproducts, which contribute to arterial aging. The results suggest a potential new therapy for reducing cardiovascular disease in the elderly.
A Mayo Clinic study has identified a significant increase in mortality from stroke among patients with heart failure. The research found that older individuals with previous strokes or diabetes were more likely to experience a stroke, leading to a higher risk of death.
A new analysis by Duke University Medical Center cardiologists found that low-dose aspirin (81 mg a day) significantly reduces death rates for postmenopausal women with heart disease, similar to higher dose aspirin (325 mg). Fewer than half of the 8,928 women in the study were taking any aspirin.
Researchers found a significant negative correlation between urine albumin levels and adiponectin hormone in obese mice. In humans, low adiponectin levels were associated with albuminuria, an indicator of kidney disease.
The TEMPO study demonstrated that over three-quarters of patients treated with Enbrel plus methotrexate experienced no progression of joint damage. Additionally, patients treated with this combination therapy showed a significant improvement in physical function compared to those receiving either treatment alone.
A new study found that increased physical activity is associated with a decreased risk of breast cancer in both black women and white women, regardless of disease stage or family history. Additionally, research on plant compound deguelin suggests it may interfere with tobacco-induced lung cancer development, while high plasma levels of...
A new study found that female rats experienced markedly increased levels of the stress hormone corticosterone compared to male rats. Chronic stress has been linked to various diseases in humans, including mental illness and autoimmune disorders, which are more prevalent among women.
The NHLBI research presented at the American Heart Association's scientific sessions highlights important findings on women and heart disease, including a link between high levels of male sex hormones and coronary artery disease in postmenopausal women. The study also explores the impact of socioeconomic status on cardiovascular diseas...
A recent study has discovered substantial room for increasing the efficiency of nanotubes, which are crucial for producing light with novel properties. The research found varying quantum efficiencies among individual nanotubes, with some being up to 1,000% more efficient than others.
A new antibody profiling technique has been developed to identify five protein markers that can detect lung cancer with high accuracy. The technique achieved 90% sensitivity and 95% specificity in identifying cancerous versus non-cancerous patient samples.
New study in Cameroon confirms declining effectiveness of malaria drugs like sulfadoxine-pyrimethamine and amodiaquine, highlighting need for alternative treatments. Researchers highlight importance of monitoring resistance and patient adherence to effective treatment regimens.
The Oxford Vascular Study found that cerebrovascular events occurred at similar ages to coronary vascular events, but stroke was more likely to cause major disability. Stroke has a greater clinical burden than heart disease in the UK due to higher rates of acute events and major disability.
A study published in Political Psychology analyzed sales data from eight Marvel comic books and found that unconventional heroes sold more copies during low-threat times compared to high-threat times. The conventional hero titles, on the other hand, remained flat in sales.
A recent study published at the Society for Neuroscience Annual Meeting found that brain activity related to face processing is similar in individuals with and without autism. The researchers used functional magnetic resonance imaging (fMRI) to examine brain function in people with autism as they processed social cues, including faces.
A new study from Johns Hopkins Medicine found that replacing carbohydrates with protein-rich foods or monounsaturated fats reduces the risk of heart disease. The study, which lasted three years, involved 164 healthy adults who followed one of three diets: high in carbohydrate, high in protein, or high in monounsaturated fat.
The University of Arizona and BIO5 Institute have received a $29 million federal grant to sequence the maize genome, enabling faster improvement of agronomically important traits in cereal crops. The goal is to unravel the complete DNA sequence of the maize plant and determine its genetic makeup.
Researchers argue that reducing carbohydrate intake is key to treating metabolic syndrome, as it can restore insulin responses and improve overall health. Studies have shown that carbohydrate reduction is more effective than fat reduction in addressing the various components of metabolic syndrome.
African-American patients with heart failure are less likely to receive implantable cardioverter-defibrillators (ICDs), despite similar prescription rates for evidence-based medicines. The disparity is attributed to lack of access to care, limited availability of cardiologists and specialized electrophysiology training.
Researchers at Forsyth Institute discover that gap junctions play a crucial role in planarian regeneration by facilitating long-range signaling. By closing down gap junctions, the team found that cells can adopt radically different fates, leading to the growth of complex structures.
The RTS,S/AS02A vaccine has been shown to reduce the risk of clinical malaria by 30% and severe malaria by 58% in a trial involving over 2000 Mozambican children. The vaccine's efficacy did not wane after 12 months of follow-up, providing sustained protection against clinical malaria for at least 18 months.
A study found that diets rich in meat, refined starches, and sodium are associated with an increased risk of persistent coughs with phlegm. The 'meat-dim sum pattern' was positively linked to new onset symptoms, while the 'vegetable-fruit-soy pattern' showed a protective effect.
A Swedish study found that women with placentas weighing at least 700 g had a 38% increased risk of developing breast cancer compared to those with lighter placentas. Higher placental weight during pregnancy may reflect elevated hormone exposure, which can increase breast cancer risk.
Researchers found that GRK2 increases in the adrenal gland, leading to high catecholamine release and desensitization of alpha-adrenergic receptors. Reducing GRK2 levels improves receptor function and reduces catecholamine release.
A recent study published in the Proceedings of the National Academy of Sciences found that nesting preferences are a crucial factor in determining whether an invasive ant species will establish itself. According to researchers, ground-nesting and arboreal ants with specific biological characteristics are more likely to succeed. The stu...
Researchers studied individual neurons in cats' neocortex to understand multisensory integration, finding that many neurons can respond to multiple senses. The findings suggest that early sensory experiences play a significant role in shaping brain circuitry, with potential implications for treating disorders such as autism and dyslexia.
The RTS,S/AS02A vaccine reduced clinical malaria episodes by 35% and severe malaria episodes by 49%. The study followed 14,442 children who received a three-dose regimen of the vaccine in 2003 for an 18-month follow-up period.
Researchers found that newly generated olfactory neurons in the adult brain can specialize in detecting previously unencountered odors and respond strongly to those smells. This suggests a unique role for these new cells in learning and memory functions, which may be important for repairing diseased brain tissue.