Peroneal nerve injuries are common in traumatic knee dislocations and require precise knowledge for surgical intervention. Sonography accurately identifies nerve injuries and their extent, enabling optimal therapy planning.
A Yale University study found that methylphenidate is an effective medication for children with autism and increased hyperactivity. However, the response rate was lower than expected compared to ADHD without co-occurring PDD.
Researchers found that individuals with autism and related disorders have difficulties distinguishing facial expressions from emotional states. The study suggests that these problems may be related to the processing of emotion rather than face perception.
The CD4 Initiative aims to create easy-to-use devices for measuring CD4+ T-lymphocytes in HIV+ patients, addressing the high cost and complexity of current technologies. The project will bring together industry know-how and scientific creativity to develop simple, rapid, and affordable tests.
A nationwide survey found that 54% of NSAID users were unaware of potential side effects, and 18% had previously experienced complications. The study emphasizes the need for patient and physician education to prevent unnecessary complications from painkiller misuse.
The study, titled 'Epidemiology of Disability and Recovery in Older Persons,' investigates the onset and resolution of disability in individuals aged 70 and above. Gill's findings suggest that disability can be reversible and often recurrent, highlighting the importance of regular exercise and pain management strategies.
The American Geosciences Institute announced the winners of its Earth Science Week 2005 contests. James Pugh won the Visual Art Contest with his drawing 'Volcanologists: It's a Hot Job,' while Robert Kendle took home the Essay Contest prize for his essay on paleontology and geoscientist aspirations.
A retrospective survey of 2,353 patients with acute cholecystitis found that laparoscopic procedure use varied widely between hospitals and years. Younger female patients in selected hospitals were more likely to receive LC for acute cholecystitis.
Researchers highlight difficulties in using substitute species, citing the need for direct examination of target species. The study concludes that surrogate species are not a viable solution to conserve endangered species.
Researchers found limited changes in brain gene activity in tame silver foxes compared to non-domesticated farm foxes. Tame foxes exhibited dramatic behavioral and physiological changes, but these were associated with only minor genetic alterations.
Hospital noise levels have grown steadily over the past five decades, exceeding World Health Organization guidelines, with human speech frequency range contributing to communication difficulties. Researchers at Johns Hopkins University found modest reductions by introducing hands-free personal communicators in patient areas.
Researchers at Penn visualize psychological stress in human brain for first time using fMRI technique, linking it to negative emotions and cognitive decline. The study provides a neuro-imaging marker of psychological stress, paving the way for improved strategies to prevent or correct long-term health consequences.
A recent study published in European Journal of Neuroscience reveals that prostaglandin E2 (PGE2) can provide protection against brain cell death by stimulating receptors EP2 and EP4. This stimulation results in increased cyclic-AMP (cAMP) levels, which reduces the toxic effects of amyloid-beta 1-42, a hallmark of Alzheimer's disease.
A large cohort study found that octogenarians undergoing open heart surgery have a 72% higher risk of death, longer hospital stays, and increased neurologic complications compared to younger patients. Age is an independent risk factor for morbidity and mortality after controlling for other variables.
Researchers analyzed the history of metabolic genes acquired by E.coli bacteria over 100 million years, finding that approximately 25 genes were added through horizontal gene transfer. This mechanism allows bacteria to evolve new functions and adapt to changing environments, rather than improving existing performance.
Bacteria use magnetosomes to distinguish 'up' from 'down' in the Earth's magnetic field and navigate to optimal growth conditions. A recent study identified a protein called MamJ that plays a crucial role in forming the magnetosome chain, enabling bacteria to sense the magnetic field.
Research suggests that longer periods of childcare can help mitigate the negative effects of a mother's low job satisfaction on her child's stress levels. Cortisol levels, a key indicator of stress, were found to be significantly higher in children whose mothers experienced emotional exhaustion or lower job satisfaction.
A recent study found that nearly one-third of clinicians surveyed do not feel confident in counselling patients who report intimate partner violence. The study also revealed that only 10% of reports documented the clinician's level of documentation, highlighting a need for improved training and protocols.
A study by Research Australia highlights the importance of commitment, funding, and collaboration in sustaining primary health care programs. The research examined five regional programs across Australia, finding that effective partnerships between organisations, leadership, and financial sustainability are crucial for long-term success.
Researchers have developed a biocompatible polymer that briefly changes from liquid to gel at body temperature to block gene-bearing viruses from leaking into the bloodstream and harming other tissues. This method reduces misdirected virus dissemination by a factor of 100-1,000 times, solving the problem of toxic leakage in gene therapy.
The Medical College of Georgia School of Nursing has received a $995,000 grant to support its new doctorate of nursing practice program, the 10th of its kind in the nation. The partnership with Emory University will prepare critical mass of nurse clinicians through increased collaboration.
A new technique successfully tracks the location of injected cells in cancer patients using magnetic resonance imaging (MRI) and iron oxide particles. The study showed that injection accuracy is critical, but not perfect, and that MRI provides an accurate way to track cells' final resting place.
Researchers at Penn State and Rice University discover how to flip molecular switches by engineering their design and surrounding environment. They demonstrated that single-molecule switches can be tailored to respond in predictable ways, depending on the applied electric field direction.
Researchers at Johns Hopkins have discovered a protein called LRRK2 that could be the best new target in the fight against Parkinson's disease. The study found that LRRK2 is involved in controlling other proteins' activities and may play a role in the death of brain cells that produce dopamine.
Nine behavioral and environmental risk factors contribute to a third of global cancer deaths. Lifestyle changes and environment modifications can prevent many types of cancer.
Researchers found that risedronate therapy significantly reduced plaque and improved periodontal status in postmenopausal women with osteoporosis. The study also highlighted the link between osteoporosis and periodontal disease, suggesting similar treatment and management may minimize tooth loss.
A study found that doctors frequently prescribe high-risk drugs despite warning labels, with noncompliance rates ranging from 12.8% to 49.6%. The authors recommend improving warning clarity, patient education, and system support to enhance adherence to recommended practices.
The APL contributed significantly to the success of the Flight Test Mission (FTM) 04-2, a live event that verified the Aegis BMD 3.0 weapon system's performance against a more difficult threat.
A team from Johns Hopkins University Applied Physics Laboratory (APL) developed a multi-purpose sensor payload to collect video and infrared imagery of the target's boost, post-boost phases, reentry vehicle separation event, and SM-3 intercept. This provided scientists with the closest view of the intercept, enabling them to better und...
A study led by Northwestern University researchers suggests that Kawasaki disease is caused by a single respiratory viral agent, entering through the lungs and infecting bronchi. The research provides new insights into the disease's cause and course, and may lead to new treatments.
ICESat measures polar ice sheets, clouds, mountains, and forests with three lasers, enabling scientists to see objects in three dimensions. The Geoscience Laser Altimeter System (GLAS) instrument has fired its one billionth shot, collecting detailed information on the vertical structure of the Earth system.
A new nanoparticle sensor developed at the University of Rochester can detect individual flu viruses and particles, setting a high bar for detection techniques. Meanwhile, researchers from the University of Twente have found that thin grooves with sharp edges can speed up drying even in humid conditions.
A recent study found that 76% of treatment-experienced patients would consider using a self-injectable HIV therapy if recommended by their physician. Despite this, only one quarter of eligible patients have discussed the option with their doctors, highlighting a significant barrier to adoption.
Researchers found that stathmin is critical for both innate and learned fear in mice. Mice lacking stathmin show reduced fear responses to stimuli, boldly exploring environments where normal mice would hesitate. This discovery advances our understanding of the neural circuitry involved in fear and offers potential therapeutic targets.
Researchers found that nine modifiable risk factors contribute significantly to cancer mortality worldwide. These include low fruit and vegetable intake, physical inactivity, and exposure to urban air pollution. Implementing lifestyle and environmental interventions can prevent a substantial proportion of cancer-related deaths.
Scientists create a new class of materials called covalent organic frameworks (COFs), which can store hydrogen more efficiently. By slowing down the synthesis process, researchers can predict the internal structure and properties of COFs, allowing for tailored applications.
Researchers at USC discovered that deleting the SIR2 gene can extend life span up to six times longer than normal when combined with caloric restriction. Human cells with reduced SIR2 activity also confirm its pro-aging effect, pointing to a new direction for human anti-aging research.
Researchers at NIST have developed a method to improve the efficiency of water chillers in large commercial buildings. By adding small amounts of oil additives to refrigerants, they claim to increase cooling capacity similar to a heat pump.
A study published in The Lancet found that pregnant women with maternal placental syndromes have a double the relative risk of premature cardiovascular disease. Women with restricted fetal growth or pre-existing risk factors for cardiovascular disease are at higher risk.
The collaboration aims to uncover the genetic basis underlying important agricultural traits in rice. By identifying sequence variation between major rice varieties, researchers can associate DNA variations with traits like drought resistance or vitamin content, ultimately helping to breed more resilient and nutritious rice strains.
A recent study found that all 50 states support dual-credit or dual-enrollment programs, allowing high school students to take college-level courses for credit. However, the research also reveals little evidence on which students are being served and how well they're preparing for college.
Researchers at National Institute of Standards and Technology (NIST) have developed a new design for X-ray sensors that can measure energies with an uncertainty of only 2.4 electron volts (eV), nearly doubling the resolution of experimental X-ray sensors. The improved design is expected to enable precise identification of the X-ray 'fi...
A recent clinical trial in Ghana found that IPTi reduced malaria by 25 percent and anemia by 20 percent in children up to 15 months old. Researchers are discussing the results at a symposium on IPTi, which has shown clear potential as a new prevention strategy for fighting malaria in Africa. Similar large-scale implementation studies a...
The Columbia Center for Homelessness Prevention Studies aims to develop effective approaches to prevent chronic homelessness by focusing on high-risk individuals and population-level prevention. The center will conduct pre-intervention research, clinical trials, and effectiveness studies to advance the knowledge base on homelessness.
Researchers have identified potential natural compounds in foods like tea, cinnamon, and buckwheat that could help lower blood sugar levels and prevent complications associated with diabetes. Cherries contain anthocyanins, which increase insulin production when tested in laboratory studies.
The National Science Foundation has awarded support for a DNA analysis laboratory at Williams College, enhancing research capabilities and integrating technology into the curriculum. The lab will facilitate studies on human DNA variants, zebrafish neural development, and Hox gene regulators, revolutionizing life sciences.
Public anxiety about a human influenza pandemic can be stemmed by governments acting transparently and issuing guidance on disease protection. This approach enables people to trust their leaders and adhere to health advice during an outbreak.
The United Nations University is building an online academy to promote sustainable development in Africa through information and communications technologies. The academy will provide online training in water, environment, renewable energy, and biotechnology, aiming to improve African competitiveness and lift productivity.
This study analyzes Thomas Jefferson's purchase of the Louisiana Territory without congressional consent, highlighting the ethical complexities of statesmanship and administrative ethics. The researcher concludes that while Jefferson's decision was morally complex, it ultimately served the nation's interests.
A Senate committee hearing explored the cause of levee failures in New Orleans following Hurricane Katrina. The investigation found that a soft, spongy layer of swamp peat underneath some levee sections may have contributed to breaches, and further analysis is needed to determine its extent.
A new study published in Science Express suggests that early Earth likely had continents and was habitable, with substantial continental crust forming by 4.4-4.5 billion years ago. The researchers used hafnium as a tracer element to infer the existence of early continental formation on Earth.
Researchers at NYU Langone Health and University of California, Berkeley, have observed the exchange of information between immune cells that sparks a body-wide response to infection. The study reveals how T cells analyze and react to signals of infection at the immunological synapse.
The VENUS observatory will support two cable arrays in British Columbia waters, enabling scientists to study the oceans continuously and access data online. The project marks a new era of ocean exploration, driven by cutting-edge technology developed in BC.
The SPICE project successfully simulated DNA strands passing through a cell membrane, a crucial process in understanding genetic information transfer. The project utilized a combination of high-performance computing and optical networks to overcome computational challenges.
Researchers at Northwestern University discovered that human embryonic stem cells can reprogram metastatic melanoma cells to a more normal state by mimicking their natural microenvironment. The findings suggest a new approach for investigating the effects of identifying key factors in reversing tumor cell properties.
Researchers identify thrombospondin (TSP-1) as a potential target for preventing acute kidney failure. Studies in mice show that the protein causes irreversible kidney damage when blood flow is disrupted, but genetically engineered mice lacking TSP-1 are protected from damage.
An international multi-center study confirmed the usefulness of a blood test in diagnosing and predicting the short-term risk of death in patients with heart failure. The study, which analyzed data from over 1,200 patients, found that the test was strongly predictive of mortality within two months of symptom onset.
Researchers developed a technique to manipulate immunological synapses with molecular precision, revealing that spatial arrangement determines signal strength. This breakthrough may help develop treatments for autoimmune diseases and better understand cellular communication.
Three New York high school students, Jedtsada Laucharoen, Alina Fradlis, and Michael Vishnevetsky, have won the prestigious Nobel Essay Contest. They will attend lectures by this year's Nobel Laureates, participate in the Prize Award Ceremony, and enjoy a traditional Swedish meal during their all-expense-paid trip to Sweden.
Patients under the care of an allergist reported significantly fewer asthma control problems, less severe symptoms, and higher satisfaction with their care. This study suggests that specialist care can lead to better outcomes for patients with chronic asthma.