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Science News for October 30, 2005


New brain tumor model developed

Researchers at Cold Spring Harbor Laboratory have identified a heretofore unknown role for the cyclin-dependent kinase inhibitor INK4C in medulloblastoma development. The study found that Ink4c inactivation cooperates with mutations in Patched to stimulate medulloblastoma formation, even when p53 is intact.

SourceCold Spring Harbor Laboratory·JournalGenes & Development·DateOct 30, 2005