Researchers find that tropical Atlantic sea surface temperature is driving increase in hurricane numbers, with human-caused cooling from pollutants tempering the effect. The study suggests global warming as a primary cause of increased hurricane activity.
The article discusses potential legislative reforms to the US medical liability system, finding that economic damage caps can lead to lower premiums. It also examines the decline of vaginal births after cesarean deliveries in California, contradicting initial expectations, and highlights the importance of preserving women's options for...
A team of Canadian and American researchers has identified the role of SHP-1 in regulating blood glucose levels and insulin sensitivity. The study used genetically modified mice to demonstrate that SHP-1 inhibition can improve glucose metabolism at the liver and muscle levels, potentially leading to new treatments for type 2 diabetes.
Researchers found no link between a fatty diet and an increased risk of skin cancer. In fact, patients who had previously been diagnosed with a skin cancer other than melanoma even had a lower risk of getting a further non-melanoma skin cancer if they reported consuming more fat.
Experts estimate that cost-effective retrofits could reduce energy use in China, India, and Brazil by at least 25%, while advanced technologies could reduce projected CO2 emission growth by 16%. Unlocking today's potential savings requires simple, highly cost-effective renovation projects to identify and eliminate energy waste.
Health researchers across Canada will investigate social determinants of health, ethnic influences on aging, and disparities among Aboriginal peoples, children, rural youth, seniors, and sexual minorities. The research aims to improve the lives of vulnerable Canadians and build stronger communities.
Researchers found correlations between DNA variants in the D4 receptor gene and self-reported sexual desire, arousal, and function. Variants affecting dopamine levels were shown to influence sexual behavior.
A new study by Princeton University researchers found that stocks with easily pronounced names tend to perform better in the short term. The effect was strongest shortly after initial public offerings (IPOs), with fluently named stocks earning up to $333 more than disfluent ones over a year.
Young Bamileke immigrants from Cameroon are using unorthodox methods to become rich, going against the general ethics of their community. The government's reluctance to address 'feymania' is undermining efforts to control corruption and criminality, strengthening the country's negative image abroad.
Researchers have identified over 1400 proteins in liver cells of mice, mapping their locations in ten different compartments. The study's findings show that around 40% of these proteins also appear in other cell organs, suggesting a high degree of conservation across species.
A team of researchers from Munich discovered a cellular mechanism that protects against tumours by controlling the Bcl-3 oncogene. The study identified Cyld as a potential tumour suppressor, which can accumulate around the nucleus and prevent Bcl-3 from entering it.
Youth with bipolar disorder show increased brain activity when rating hostile faces, indicating difficulty processing emotional cues. This finding may help refine diagnosis and understanding of the underlying brain mechanisms.
A Queen's University study discovered a new heterodimer formed by COX-1 and COX-2 enzymes in genetically modified mice. This finding may impact the development of alternative anti-inflammatory drugs, potentially reducing cardiovascular risks associated with existing pain medications.
Researchers have discovered a promising drug target, LipB, essential for M. tuberculosis survival and replication. The protein's structure has revealed its activity in activating cellular machines driving the bacterium's metabolism.
Scientists find VIAAT enables joint storage of GABA and glycine in vesicles, refuting dogma that GABA release is crucial for nerve cell growth. VIAAT mutant mice develop normally despite GABA and glycine release elimination.
Researchers found that a bacterial parasite, Pasteuria ramosa, produces intermediate levels of virulence to maximize spore production and host fitness. This tradeoff between host and parasite fitness has important implications for public health strategies to contain emerging parasitic diseases.
A recent study by Penn State researchers found that 89% of patients with diagnosed Crohn's disease showed improvement with therapy using naltrexone, while 67% achieved remission of symptoms. The treatment has been shown to be simple, safe, and cost-effective compared to traditional steroid treatments.
A Dartmouth study found that arsenic in drinking water can inhibit DNA repair, leading to increased cancer risks. The researchers measured arsenic levels in urine and toenails of participants in New Hampshire and Mexico, and found a correlation between high arsenic levels and impaired DNA repair.
Researchers found that flagella in algae allow for active nutrient gathering, concentrating nutrients just ahead of the moving colony. This discovery explains how single-celled life forms can evolve into larger multicellular organisms like Volvox, a colony of up to 50,000 cells.
Researchers have developed a new technique to detect and identify wound bacteria, significantly reducing the time it takes for lab personnel to figure out what type of bacteria is present. This allows for more accurate treatment to begin sooner, which can help prevent antibiotic resistance.
A study of 295 children with JRA found that Medicaid recipients had higher disease activity, more pain, and lower physical function compared to those with private insurance. The reasons for these disparities are not yet clear, but may be linked to non-treatment-related factors such as poverty and adherence to treatment.
A new clinical trial at Penn aims to compare two embolic agents for treating uterine fibroids, with the goal of reducing symptoms and improving outcomes. The study will enroll 60 patients and last approximately nine months.
Researchers found that mice lacking MHC Class I molecules can still mount an effective CD8 T cell response against chronic herpes virus infections. This suggests the presence of a backup immune system component that can recognize and fight viral proteins without relying on MHC Class I.
Pre-diabetes and undiagnosed type 2 diabetes affect millions, increasing heart disease risk. Research shows nearly 22% of people aged 65+ have diabetes, with significant disparities among ethnic groups.
A European-funded project aims to create a predictive diagnostic test for early detection of kidney loss and target effective therapies. Researchers will utilize nanobead technology and multiplexing platform to identify biomarkers in diabetic urine, enabling early identification of patients at risk.
A study published in Evaluation Review highlights the dangers of firearms in intimate partner violence cases, with women twice as likely to die from gunshot wounds inflicted by male intimates. The research explores potential solutions such as restraining orders, gun removal, and denial of gun purchases to intimate partner abusers.
Researchers found that malaria and potato famine pathogens use similar protein sequences to infect cells, but deliver different toxic proteins. This discovery could lead to the development of a dual-purpose drug targeting both Plasmodium falciparum and Phytophthora infestans.
Researchers found SIVcpz infection in up to 35% of chimpanzees in West Africa, allowing for genetic comparisons between HIV-1 and its simian counterpart. The study provides insights into the origins of HIV-1 and how it made the jump from animals to humans.
Researchers at FSU have produced high-resolution images of the HIV virus, revealing its complex molecular surface architecture and enabling the development of more effective vaccines. The study, published in Nature, provides valuable insights into the virus's structure and behavior, which could lead to breakthroughs in vaccine design.
A recent study published in the journal Stroke found that clipping and coiling treatments for aneurysms produce similar long-term outcomes. The study followed 1,010 patients treated between 1996 and 1998 and revealed that rerupture of the aneurysm occurred at a lower rate in clipped patients compared to those who received coiling treat...
A study of 2,512 community-dwelling elders found that those with limited literacy were more likely to report poor overall health and diabetes, as well as depression. This is partly due to difficulties in reading health information, managing medications, and navigating the healthcare system.
Two surgical interventions, primary peritoneal drainage and laparotomy, were compared in a clinical trial involving 117 preterm infants with perforated NEC. The study found that the type of operation performed did not influence survival or other clinically important outcomes.
The study found that ethnicity, quality of the doctor-patient relationship, disease activity, and trust in the US healthcare system are all associated with patients' trust in their doctors. Patient-centered communication was significantly linked to increased information sharing by patients.
Researchers found that atorvastatin increased circulating endothelial precursor production by 1.7 to 8-fold in SSc patients, improving Raynaud's phenomenon activity but symptoms generally returned to baseline after discontinuation.
A recent study found 14 cases of direct adverse events associated with pediatric spinal manipulation, including serious events like hemorrhage and paraplegia. The research team is now working on developing a more effective reporting system to collect data on outcomes, including harms.
Researchers have identified new biomarkers that correlate with patient response to anti-TNFá therapy, improving the treatment of spondylarthritis. The study found changes in synovial tissue features, such as macrophage and PMN cell changes, associated with disease activity and treatment effectiveness.
A recent study found that bacteria can utilize DNA as a critical food source, enabling them to outcompete other microbes and survive longer. The study identified eight genes necessary for this process, known as nutritional competence, which could have applications in medical research and the development of genetic antibiotics.
UT Southwestern researchers found that a Yersinia outer protein called YopJ cripples host enzymes, preventing the immune response and allowing the bacteria to survive. The study presents a new paradigm for how cells regulate signaling and could lead to a better understanding of host-pathogen interactions.
Researchers predict that braneworld black holes, created in the early universe, have survived and can be detected by observing gamma-ray bursts passing near them. The signature of these black holes could provide evidence for a fourth dimension of space.
Researchers observed eruptive activity at Northwest Rota-1 for three separate visits over two years, suggesting chronic eruptions. They used an underwater robot to observe explosive activity from 10 feet away, gaining clearer insights than possible on land.
Dental caries is a widespread and increasing problem globally, with 5 billion people affected. Forsyth researchers aim to develop a vaccine targeting bacterial accumulation on teeth, with initial focus on mucosal vaccines for young children.
The ITTO report reveals that sustainably managed tropical forests have expanded from 2.4 million acres in 1988 to at least 87 million acres in 2005. However, the majority of forest land being managed sustainably comprises less than 5% of total surveyed areas.
Carbon nanotubes have withstood pressures up to 40 gigapascals, making them ideal for nanoscale hydraulics and cylinders. The researchers discovered that nanotubes can perform similar functions at the scale of atoms and molecules, including extrusion processes.
Researchers used tree-ring records and gauged streamflows to reconstruct historic Colorado River streamflows, dating back to 1490. The reconstructions suggest that droughts more severe than the recent 100-year period occurred in the past, with at least eight droughts similar in severity to the 2000-2004 drought.
Researchers found that parasites can modulate immune responses and reduce inflammation in inflammatory bowel disease. The study suggests that improved hygiene may be responsible for the rise of IBD in developed societies.
Researchers at Duke University have reported a theoretical blueprint for an invisibility cloak made of metamaterials. The cloak can hide objects so well that observers are unaware of their presence, similar to how water flows around a smooth rock in a river. This technology has potential applications in wireless communications and acou...
Researchers have developed a new approach to target different diseases using short interfering RNA (siRNA) with tailored cellular properties. Human trials for siRNA-based anti-cancer and anti-viral treatments are currently underway in the USA and Europe, offering promising results.
A study by Saint Louis University found significant changes in brain activity after vagal nerve stimulation treatment began, continuing to evolve over 21 months. The treatment appears to induce long-lasting brain changes, with benefits lasting up to two years.
Researchers identified mutations in the AIP gene as the underlying cause of pituitary adenoma predisposition. The discovery provides molecular tools for efficient identification of predisposed individuals, potentially leading to earlier diagnosis and treatment of conditions like acromegaly and gigantism.
Researchers Harry Roberts and Bob Carney are studying the animals that live near oil and gas seeps in the Gulf, including bacteria that feed on hydrogen sulfide gas. They will use the Alvin submersible to take them down to the bottom of the Gulf, where they hope to discover new species and learn more about these unique communities.
NIST researchers create a microfluidics technique to isolate and pattern neuronal cells on surfaces, allowing for the study of cell development and behavior. This breakthrough enables a variety of cell-geometry experiments, such as measuring the maximum gap between lines that can be bridged by neural axons and dendrites.
Two surgical procedures, laparotomy and bowel resection, and peritoneal drainage, were compared in a multi-center randomized controlled trial. The study found that patient survival rates and major outcomes were virtually identical between the two procedures.
A study conducted by Yale University researchers found that Iraqi nurses require improved working conditions, equipment, and financial support to ensure the success of the healthcare system. The nurses also emphasized the importance of respect from physicians, administrators, and society at large.
Ignoring Indigenous communities' health experiences under current MDG policies puts them at risk of disappearing forever. The Lancet series highlights the importance of including Indigenous wisdom and rights in international health and medicine.
Researchers found that magnesiowüstite, a common mineral in the lower mantle, absorbs infrared light when compressed to extreme pressures. This suggests that radiation may not play a significant role in heat flow near Earth's core.
Phase 3 clinical trials demonstrate desvenlafaxine succinate's effectiveness in reducing depressive symptoms and improving quality of life for adult patients. The medication also showed promise in managing depression-related pain, highlighting its potential as a valuable treatment option.
Researchers found that defendants rated as 'stereotypically black' were sentenced to death at a rate of 57.5%, compared to 24.4% for those less stereotypically black, in cases involving white victims. However, this effect disappeared in 'black-on-black' capital cases.
A multicenter randomized controlled trial involving 117 premature infants found that laparotomy and bowel resection and peritoneal drainage surgical approaches have essentially the same major outcomes in terms of patient survival. The study ends three decades of speculation and debate over which approach is more effective.
The Lancet series highlights disparities in indigenous people's health worldwide, with lower life expectancy, higher rates of infectious diseases, and poor access to healthcare. Researchers are calling for greater respect and action to address these issues and preserve unique knowledge about ecosystems and medicines.
Research reveals that non-pathogenic bacteria from cow manure share antibiotic-resistance genes with multi-drug resistant Salmonella strains on the same farm. Ecology appears to play a major role in the spread of drug resistance, rather than therapeutic antibiotic use.