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Science News for December 5, 2007


Diesel exhaust fumes affect people with asthma, finds study on London's Oxford Street

A new study by Imperial College London found that diesel exhaust fumes increase asthmatic symptoms, reduce lung capacity, and cause inflammation in people with mild and moderate asthma. The research measured air quality and lung function in volunteers walking along Oxford Street, where only diesel-powered vehicles are allowed.

SourceImperial College London·JournalNew England Journal of Medicine·DateDec 5, 2007

Biomarkers for inflammatory disease

Researchers characterized gene expression patterns in Kawasaki disease patients, identifying innate immune mechanisms and proinflammatory responses. The study supports the use of gene-expression profiles to generate biomarkers for other systemic inflammatory illnesses, improving diagnosis and treatment options.

SourceBMC (BioMed Central)·JournalGenome Biology·DateDec 5, 2007

Study questions impact of hemoglobin variations on mortality in dialysis patients

A recent study published in the Clinical Journal of the American Society of Nephrology suggests that persistently low hemoglobin levels in dialysis patients increase their risk of death, while fluctuating levels do not. The research used data from nearly 160,000 patients to analyze the effects of hemoglobin variability on mortality rates.

SourceAmerican Society of Nephrology·JournalClinical Journal of the American Society of Nephrology·DateDec 5, 2007

How stress alleviates pain

Researchers found that stress hormone noradrenaline suppresses pain inputs from the brainstem, reducing neurotransmitter launch and triggering nerve impulses. The study provides important mechanistic clues to understanding stress-induced analgesia.

Odd little star has magnetic personality

A team of astronomers, led by Dr. Edo Berger, have observed a surprisingly active magnetic field on the ultracool low-mass star TVLM513-46546, challenging the theory that cooler stars are simple and quiet. The star's complex magnetic field environment may indicate unusual activity beneath its surface or possibly even an unseen companion.

Reviewers agree on osteoarthritis of the knee

A review of six knee osteoarthritis treatment guidelines found significant differences in recommended treatments, with a focus on acetaminophen, NSAIDs, and exercise. The study highlights the need for more detailed educational interventions to improve guideline applicability.

SourceBMC (BioMed Central)·JournalArthritis Research & Therapy·DateDec 5, 2007

Scientists strike blow in superbugs struggle

Researchers at the University of Manchester have pioneered new methods to modify antibiotics' molecular structure, enabling the development of new types of antibiotics capable of combating increasingly resistant bacteria. This innovation provides access to thousands of lipopeptide variants that cannot be produced easily in any other way.

SourceUniversity of Manchester·JournalJournal of the American Chemical Society·DateDec 5, 2007

Humans appear hardwired to learn by 'over imitation'

A Yale University study found that children follow adults' actions faithfully, even when they are unnecessary, leading to confusion and difficulties in learning. The research suggests that children's ability to imitate can actually hinder their learning process if they observe an adult performing inefficient behavior.

SourceYale University·JournalProceedings of the National Academy of Sciences·DateDec 5, 2007

Beating hospital yeast infection

A systematic review of over 5,500 patients found that both single-drug antifungal prophylaxis (SAP) and selective digestive tract decontamination (SDD) reduce yeast-related morbidity and mortality. SDD was more effective in reducing yeast colonization and infection, while SAP responded best to candidemia.

SourceBMC (BioMed Central)·JournalCritical Care·DateDec 5, 2007