Researchers are developing novel antibacterial compounds targeting MRSA, a life-threatening drug-resistant infection. The new medicines block the ability of MRSA bacteria to divide and multiply, reducing resistance levels.
Researchers discovered a new genetic variant SORL1 associated with late-onset Alzheimer's disease. The gene is linked to an increased risk of toxic amyloid beta peptides in the brain, leading to Alzheimer's disease.
Researchers have identified a new genetic clue that may contribute to the development of late-onset Alzheimer's disease. Variations in the SORL1 gene were found to be associated with an increased risk of the disease, and altering the levels of this protein changed the way amyloid beta fragments were produced in cells.
A new study has identified a gene that regulates adult stem cell growth, which could lead to increased doses of chemotherapy and faster recovery times for cancer patients. The discovery also opens up possibilities for treating other diseases such as liver disease and diabetes.
Researchers identified a new genetic risk factor associated with late-onset Alzheimer's, implicating the SORL1 gene. Variants of this gene are linked to an increased risk of Alzheimer's, particularly in Caucasians, and may play a role in the production of toxic amyloid-beta fragments.
A survey of 127 specialist registrars reveals that nearly a third view working with patients directly in community settings as a bad development. The respondents felt poorly prepared to meet the challenge and wanted additional training, but only half believed this would improve their job prospects.
Researchers found that a drug blocking nitric oxide synthesis significantly reduced tumor blood volume in patients, providing early clinical evidence of its anti-vascular activity. The study's results suggest potential for the use of this agent as a novel vascular targeting agent in cancer treatment.
Researchers found that 71% of lost dogs were reunited with their owners, compared to 53% of lost cats. Identification tags or microchips played a crucial role in recovery. Posting signs and advertising in local newspapers also helped recover pets.
Scientists at ProXara Biotechnology Limited have identified a way to prevent tumour cells from growing by switching off key enzyme PKB. The research, funded by the Wellcome Trust Seeding Drug Discovery initiative, aims to develop a drug that can be used in clinical trials for lung cancer treatment.
Researchers have identified pancreatic polypeptide as a potential solution to appetite suppression, which may lead to a new obesity treatment. The hormone is naturally released in the gut and acts as a neurotransmitter to indicate fullness to the brain.
Researchers at the University of Toronto have identified a new gene, SORL1, associated with an increased risk of Alzheimer's disease in different ethnic groups. The discovery highlights the complexity of the disease's genetics and underscores the need for further replication studies.