A new study found that green tea's EGCG ingredient can rescue mice from lethal sepsis, paving the way for clinical trials. The substance works by preventing HMGB1 from being released and activating immune cells.
Researchers at NIST and George Mason University have created a tiny microwave oven that can heat a pinhead-sized drop of liquid with precision. The micro microwave is designed for lab-on-a-chip devices, which perform rapid chemical analyses on tiny samples.
Ozone intrusions are associated with sudden changes in tropopause altitude, damaging forests and crops. The study uses windprofilers to monitor ozone movements, highlighting the need for a better understanding of the role of human activities in atmospheric pollution.
A recent genetic study found that higher vitamin D levels are linked to improved genetic measures of lifelong aging and chronic stress. Vitamin D may also play a role in reducing the risk of heart disease and certain cancers.
A physicist has developed a novel technique to speed up scanning tunneling microscopy, enabling it to image individual atoms on a surface at least 100 times faster. The new method uses radio frequency waves to detect changes in distance between the probe and sample surface, reducing measurement times by several orders of magnitude.
Researchers have found that peanut husks can extract up to 95% of copper ions from waste water, while pine sawdust achieves only 44% extraction. The process works best at slightly acidic conditions, making it a promising solution for reducing toxic copper levels in natural resources
A single amino acid variation in equid herpesvirus type 1 (EHV-1) creates a different type of EHV-1 that causes neurological disorders in horses. The researchers found that altering this amino acid reduces virus levels and makes the virus more susceptible to antiviral drugs.
A study by scientists has found that the most energetic particles in the universe – ultrahigh-energy cosmic rays – are correlated with the centers of active galaxies hosting violent black holes. The sources are thought to be within 326 million light years, our local neighborhood in cosmic terms.
A recent study by Dr. Dorit Hanein at the Burnham Institute for Medical Research provides new insights into Familial Hypertrophic Cardiomyopathy (FHC), a deadly genetic disorder affecting young people and athletes. The research reveals that a specific point mutation in myosin heavy chain causes myocardial disarray, leading to changes i...
The TOWARD study confirms Actemra plus DMARDs significantly improves RA symptoms and clinical remission rates compared to traditional DMARDs alone. Additionally, Actemra shows rapid normalisation of inflammation markers and improved quality of life in patients with rheumatoid arthritis.
A Chinese-Australian research team studied the whitefly Bemisia tabaci's invasive behavior, discovering that it breeds more when interacting with native populations and suppresses their reproduction rates. This asymmetrical mating interaction drives the widespread invasion and displacement of native species.
Researchers identified atrogin-1 as a key factor in statin-induced muscle damage, which can be prevented by inhibiting its function. This breakthrough may lead to new treatments for high cholesterol patients experiencing unwanted side effects.
Researchers at UBC discover a process called chromatin remodeling that allows certain cancer cells to hide from the immune system by altering the structure of chromosomes. This 'instruction manual' enables cancer cells to evade detection and grow unchecked, but the discovery may lead to new therapies within five to 10 years.
A study of over 3,200 northern Manhattan adolescents found that Hispanic youths had better dental health habits than their black peers. The study also revealed higher rates of cavities and moderate-to-abundant plaque among black youth.
A new study found that dieters who eat in response to emotions, rather than social situations, tend to lose less weight and experience more weight regain. Emotional eating was associated with lower weight loss and higher likelihood of regaining weight in successful losers.
Scientists from 17 countries identify Active Galactic Nuclei (AGNs) as the most likely source of the highest-energy cosmic rays using data-gathering equipment designed at Michigan Tech. The findings, reported in Science journal, bring researchers closer to understanding the origin of ultra-high energy particles.
Scientists have discovered a method to track neural progenitor cells in the adult human brain, opening new avenues for diagnosis and treatment of neurological disorders. The breakthrough uses magnetic resonance spectroscopy (MRS) to detect proteins produced by these cells.
A new UCLA study reveals that people seeking antiretroviral medications after high-risk sexual encounters are likely to complete the full treatment regimen. The research also shows a strong demand for publicly available post-exposure prophylaxis among high-risk populations in Los Angeles County.
Researchers developed a top-down analytical approach to understand schizophrenia's symptom inconsistencies, linking them to instability in attractor neural networks. The study suggests that decreased excitatory NMDA-mediated synaptically activated receptor conductances contribute to attention difficulties and reduced emotions.
The Pierre Auger Observatory has found that active galactic nuclei, powered by super-massive black holes, are the most likely source of the highest-energy cosmic rays. The sources of these particles are not distributed uniformly across the sky, but rather linked to nearby galaxies with active nuclei.
A city-wide sanitation intervention in Salvador, Brazil, significantly reduced diarrhoea prevalence among children, with a 22% decrease. The study found that diarrhoea was 43% lower in areas with the highest baseline prevalence of diarrhoea.
Researchers have developed a genetic identity card for Plasmodium falciparum populations, revealing high genetic diversity and inbreeding rates. The study's findings can help predict changes in genes involved in drug resistance, enabling targeted therapies to minimize resistance development.
A meta-analysis of decades of scientific study reveals a small but statistically reliable tendency for men to be more talkative than women overall, especially in conversations with strangers. Women tend to dominate conversations with children and close friends, while using speech to build connections with listeners.
The Pierre Auger Observatory has found that the sources of the highest-energy cosmic rays are linked to nearby galaxies with active nuclei in their centers. This discovery provides new insights into the origin and acceleration of these particles.
A study of 240 patients with acute low back pain found that adding diclofenac or spinal manipulative therapy to recommended first-line care did not significantly reduce recovery time. Both treatments showed no clinically useful benefits, highlighting the importance of baseline care for managing acute low back pain.
A new study reveals that wild house mice rely on specialized protein signals in their urine to recognize and avoid close relatives. The researchers found that these proteins serve as a genetic barcode, allowing animals to identify and reject potential mates based on their unique scent profiles.
Researchers compared 12 closely related fruit fly species to better understand genetic adaptation, immune systems and gene regulation. The study, led by Cornell University, found evidence of evolutionary pressures on genes and regulatory elements that control diseases, development and behavior.
Researchers have found a significant correlation between high-energy cosmic rays and the cores of nearby galaxies, which emit prodigious quantities of energy. The Auger collaboration has traced the source of these cosmic rays to Active Galactic Nuclei (AGN), likely powered by supermassive black holes.
Research from RAND Corporation reveals California's preschool system is not maximizing child development and school readiness benefits. High-quality preschool programs serving disadvantaged groups can improve academic performance, but the state's current system has low standards and little incentive for providers.
Scientists have developed a non-invasive method to track neural stem and progenitor cells in the live human brain using MRI technology. This breakthrough could lead to better diagnosis and monitoring of brain tumors and serious neurological disorders.
Virginia Commonwealth University researchers have discovered a new mechanism to inhibit key enzymes involved in clotting disorders. The newly designed molecules, known as sulfated DHPs, show promise in preventing thrombin and factor Xa's critical action.
Locally advanced breast cancer (LABC) may account for 50% of breast cancers in developing countries and 30% among socially disadvantaged women. A new study identifies a molecular switch essential for LABC development, which could be targeted for new therapies.
Scientists at the University of Utah report that Yellowstone's caldera floor has risen by almost 3 inches per year for three years, with a total uplift of 7 inches during the past 30 months. This rate is more than three times faster than previous observations and may be due to an injection of a Los Angeles-sized blob of molten rock.
A study by Johns Hopkins Medicine reveals a subset of adult brain cells that can exhibit dynamic behavior, including elongation and morphing, unlike traditional adult axons. This discovery opens up new avenues for understanding neural recovery following stroke or other brain trauma.
Researchers performed the world's smallest double slit experiment using a hydrogen molecule, demonstrating classical behavior at the quantum level. The results show that quantum particles start behaving in a classical way on a scale as small as a single hydrogen molecule.
Researchers at Cornell University have identified a hormone in human urine that can safely reduce sodium levels and treat hypertension. The discovery was made possible by a new technique developed by Frank Schroeder, which allows for the analysis of complex mixtures of small molecules.
A national study found that long-term pegylated interferon does not prevent the progression of liver disease in patients who haven’t responded to previous treatments. Despite significant viral level decrease and inflammation reduction, 34.1% of treated patients experienced worsening outcomes.
A RAND Corporation study finds that advanced diesel technology outperforms hybrid technology, which in turn beats gasoline-powered cars. Diesel vehicles provide larger savings for consumers and society, while hybrids offer moderate-to-small benefits.
Research reveals that statins cause skeletal muscle damage through the activity of the gene atrogin-1. Inhibiting this gene's function could help protect against the side effect. Separate studies also link low levels of protein SHGB to metabolic syndrome and show how excess sugar contributes to its development.
A recent study by Arizona State University professor James Elser found that ecosystems are not as different as they seem when it comes to nutrient limitation. The study analyzed over 300 publications and found that nitrogen and phosphorus are equally important in freshwater systems, contradicting conventional wisdom.
A novel molecular switch controls protein synthesis to promote tumor growth and survival in locally advanced breast cancer. The switch is regulated by two factors, 4E-BP1 and eIF4G, which are strongly over-expressed in human large advanced breast tumors.
Geologists at the University of Illinois report a direct relationship between magma production and tectonic plate convergence rates in a Caribbean submarine volcano. Analyzing rock samples from Kick'em Jenny, they found a higher protactinium-to-uranium ratio indicative of slower melting rates due to slow subduction rates.
Researchers have discovered that the FTO gene influences weight gain by modifying DNA, suggesting a role in controlling hunger and satiety. The study found that the FTO variant is common and associated with increased risk of obesity and diabetes, paving the way for potential therapeutic manipulation.
A study reveals that excess sugar consumption decreases SHGB production in the liver, a protein regulating sex steroid entry into tissues. This reduction is associated with increased fat palmitate levels and inhibited by inhibiting palmitate generation.
A team of scientists, led by Marek Pfutzner, has successfully peered closely at the radioactive decay of a rare iron isotope, shedding light on an exotic form of radioactivity. The technique used a novel combination of advanced physics equipment and digital camera technology to capture ghostly images of trajectories of emitted protons.
Researchers propose a broader approach to uncovering the causes and consequences of obesity, highlighting similarities in cell responses to excess nutrients. This understanding might reveal why overeating leads to various diseases and explain animal longevity on calorie-restricted diets.
Cornell researchers identified a natural amino acid called meta-tyrosine in fescue lawn grass that inhibits weed growth and suppresses plant development. The discovery may lead to the development of new varieties of fescue grasses with improved weed-suppressing properties.
Current oral contraceptive users have a higher risk of developing cervical cancer, but this risk returns to normal after 10 years of not using the contraceptives. The study also found that women who test positive for high-risk human papillomavirus are more likely to develop in-situ or invasive cervical cancer.
Researchers have identified a potential new way of fighting against HIV infection by targeting human endogenous retroviruses (HERV). A vaccine containing HERV antigens could stimulate T-cells that target cells expressing HERV, potentially protecting people from becoming infected or limiting damage caused by HIV.
A study involving grade 12 students found that most teens associate Remembrance Day with World War I and II, but don't consider its relevance to contemporary events. However, the majority believe the day plays a significant role in shaping national identity.
A new study published in The Lancet has shown that urban sanitation is a highly effective health measure in reducing cholera and diarrhoeal diseases in developing countries. The research found that city-wide sanitation programs can reduce the prevalence of diarrhoea by up to 43% in high-risk areas.
Researchers at Harvard and Johns Hopkins Universities developed a new paradigm in calculating tumor development, finding that it's driven by mutations in hundreds of genes. The study suggests that individual tumors can be driven by up to 20 mutated genes, leading to better understanding and potential new treatments for cancer.
Researchers found that a multifaceted approach including psychoeducational groups and treatment adherence support led to significant clinical improvements in low-income mothers with postnatal depression. The study suggests that this intervention could be effectively implemented in developing countries, reducing the adverse effects of p...
Researchers at Ohio State University Medical Center found that the mitochondria send a death signal to cardiac cells when blood flow is restored, leading to cell damage and weakening heart function. The study identifies a specific enzyme, mitochondrial nitric oxide synthase, as a potential therapeutic target to stop this process.