A recent study by Harvard researchers found that coronary CTA is more cost-effective than current tests for diagnosing low-risk women with acute chest pain. The study suggests that CT angiography can reduce total healthcare costs by $380 and emergency department costs by $410 compared to standard care.
Researchers at the Institute for Animal Health are developing complex models to understand how bluetongue virus spreads among livestock. By analyzing midge numbers, biting behavior, and weather patterns, they aim to provide farmers with critical information on when to move animals and implement best practices for controlling the spread...
Researchers have created disease-specific stem cell lines for ten genetic disorders, including muscular dystrophy and Parkinson's disease. These lines will enable scientists to model human diseases in a laboratory setting, making it possible to study the development of various tissues relevant to these conditions.
Researchers at the Salk Institute have discovered that a protein called IKK2 plays a crucial role in regulating de-granulation, a process involved in allergic reactions. By targeting IKK2, scientists hope to develop acute inhibitors for treating allergies and potentially other diseases.
A new study reveals that when people try to make a positive impression, they may behave in ways that contradict gender stereotypes. Men and women in high-status roles acted in ways that contradicted traditional gender norms during negotiation simulations.
A new study published in Journal of the Science of Food and Agriculture found no evidence to support the view that organically grown crops contain more major and trace elements. The study compared retention of minerals and trace elements in animals fed a diet consisting of conventionally grown crops, organic crops, and a combination of...
A new study has pinpointed genetic variations in European Americans, which may help isolate the genetic basis for disease and population variation. By analyzing DNA data from 1,521 individuals, researchers identified 200 positions within the DNA helix that capture much of the genetic diversity in this complex population.
A new study has discovered a specific brain association in people with borderline personality disorder, linked to difficulties in understanding others' actions. The findings suggest a potential diagnostic tool and treatment approach using functional MRI technology.
The study reveals that the formation of planetary systems was full of violence and drama, but our solar system required conditions to be just right. The researchers ran over 100 simulations, showing that an average planetary system's origin was dramatic, with planets being flung into space or crowded together.
The review discusses how mouse genetics research has contributed to a better understanding of human health and disease. Researchers predict that creating 'humanized' mice will provide new experimental systems for testing novel therapeutics.
A recent study suggests that a specific biochemical process in the placenta may contribute to postpartum blues and depression. The researchers propose that an imbalance in serotonin levels, triggered by the withdrawal of interleukin-1 beta after birth, may lead to symptoms of depression.
Researchers at the University of Southern California have observed a clean three-way split in a molecule for the first time. The study uses a sym-triazine molecule and energizes its electrons to create identical and equally energetic parts.
Researchers at NYU Cancer Institute have identified mebendazole as a potential treatment for metastatic melanoma, exploiting its ability to target cancer-causing proteins. By inactivating the protein Bcl-2, mebendazole induces programmed cell death in malignant melanoma cells.
A new study reveals that p53 regulates cells by inhibiting the mTOR pathway, which regulates cell growth. The discovery of Sestrin1 and Sestrin2 as key players in this process may lead to novel cancer preventives and therapeutics.
Clinician-scientists in the UK are struggling with a lack of career support, limited research training opportunities, and significant medical school debts. However, new funding and mentorship programs may help alleviate these challenges and preserve this vital profession.
Asterion Ltd.'s patented ProFuse technology enables the creation of longer-acting drugs to tackle major diseases. The company's platform can also be used to develop pairings between therapeutic hormones and protective receptor domains to address conditions like some cancers, anaemia, infertility, and diabetes.
A study found that only 23% of stroke patients arrived at the hospital within two hours of symptom onset, making them suitable for time-dependent therapies like tPA. Patients who arrived by ambulance or received care at Primary Stroke Centers were more likely to receive a timely CT scan.
Researchers are investigating SEP transport in 3D heliospheric magnetic fields to understand why some events occur without magnetic connection to the Sun. The goal is to assess cross-field diffusion's role in charged particle transport.
Researchers at Boston Children's Hospital have developed 20 disease-specific stem cell lines for conditions such as Parkinson's Disease, Down Syndrome, and Muscular Dystrophy. These lines were created using the iPS technique and will be made available to researchers worldwide.
A new survey reveals that 33% of individuals with diabetes who take insulin injections experience dread related to them, while 52% do not proactively discuss their concerns with healthcare providers. However, many healthcare professionals are aware of the impact of insulin injections on patients' quality of life and have initiated dial...
Researchers discovered a gene linked to melon sex switching, which suggests evolutionary selection favoring the mutation. This finding provides insights into the molecular basis of sex determination and different sexual systems in plants.
A novel mutation in the nephronophthisis 4 (NPHP4) gene has been identified as a potential cause of cone-rod dystrophy in standard wire-haired dachshunds. This discovery raises hopes for developing treatments for humans with similar eye disorders.
Thakur's work has advanced excellence in healthcare through the development of radiopharmaceuticals and imaging techniques, including a new monoclonal antibody for detecting infection. The 2008 Benedict Cassen Prize recognizes his major advance in basic or clinical nuclear medicine science.
According to a new survey, 82% of Americans believe the US healthcare system should be fundamentally changed or rebuilt. The survey found that one in three patients experience unnecessary or inefficient care, while nine out of ten adults support efforts to improve the health system's performance with respect to access, quality, and cost.
The University of Texas at San Antonio's MBRS/RISE program will provide funding and professional development opportunities to up to 55 undergraduate and doctoral students from underrepresented minority groups. The program aims to develop the next generation of biomedical researchers through hands-on research experience and training.
Scientists at Boston Children's Hospital have identified the Otx2 protein as a key factor in triggering brain plasticity, allowing the brain to rewire and adapt. This discovery has implications for understanding developmental disorders like autism and potential treatments for improving learning and cognitive function.
A new study confirms a link between warmer climates and more powerful rainstorms, increasing the risk of flooding and societal impacts. Researchers found that tropical rainfall extremes increase during warm periods, with heavy downpours boosted by atmospheric moisture.
A new technology developed at Purdue University detects trace amounts of explosives, drugs, or other materials left behind in fingerprints. It can also distinguish between overlapping fingerprints, a difficult task for current optical forensic methods.
Scientists at Tufts University have demonstrated a new class of sensors combining nanoscale optics with biological readout functions, enabling biocompatible and biodegradable sensing technology. The developed silk-based optical elements can be used to detect harmful levels of bacteria in food and monitor glucose in the blood.
The Lancet recommends allowing newborn infants to participate in multiple clinical studies with their parents' consent, provided it does not compromise care or safety. This would strengthen the evidence base for medical care of newborn infants and balance ethical concerns.
The Citipix Collection, valued at over $14.3 million, is a historic snapshot of urban history in the US at the turn of the century. The collection consists of 500,000 color-stereo images taken between 1999-2002, providing clear detail up to six inches off the ground.
A large cohort of Danish children with up to 28 years of follow-up showed that death after febrile seizures is extremely rare. Children who had simple febrile seizures had mortality similar to the general population, but those with complex febrile seizures had a two-fold higher risk of death within two years.
The University of Houston's Texas Obesity Research Center (TORC) is recruiting 500 participants for a study promoting healthy dietary habits and physical activity in the virtual world of Second Life. Participants will earn rewards and compete to win the International Health Challenge.
Researchers explore new treatments for psoriasis, revealing a potential therapeutic option in AEB071, while cautioning further clinical trials are needed. Additionally, studies uncover the reasons behind gene therapy complications in SCID patients, shedding light on insertional oncogenesis and acquired somatic mutations.
Clinical Research Management has secured a seven-year contract to conduct Phase I Clinical Trials for Therapeutics against Infectious Diseases at three national testing sites. The sites are Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, and Johns Hopkins University. Each site will recei...
Researchers discuss the difficulties in diagnosing and treating Barrett's oesophagus, a pre-cancerous condition often associated with chronic acid reflux. The authors suggest improving detection and treatment by developing standardized indicators, less costly screening methods, and laboratory animal models.
The project utilizes physiological information to develop more sophisticated assistive aids for individuals with neuromuscular diseases and musculoskeletal injuries. Researchers aim to create robotic orthoses that can aid patients with muscular dystrophy regain significant use of their limbs.
Researchers at UGA are working to improve the efficiency of converting lignocellulose into ethanol using switchgrass and sunflower, with potential benefits for reducing carbon dioxide emissions and food costs.
Researchers have adapted a human test to screen for elevated iron levels in marmosets and tamarins, enabling early identification and treatment of hemosiderosis. This diagnostic tool also helps veterinarians provide tailored care to individual animals.
B cells can activate themselves in autoimmune diseases without T cell assistance, leading to a 'vicious cycle' of chronic disease. This finding may explain why treatments targeting T cells have been less effective and newer B cell-targeted therapies show promise.
Researchers found no correlation between traditional and standardized assays, highlighting the need for a physiologically relevant platform. Clade C antibodies showed broad cross-reactivity, neutralizing multiple viruses in both formats.
Researchers at Harvard Medical School have successfully used RNA interference (RNAi) to prevent the spread of HIV in mice. The study found that knocking down three specific genes in T cells protected them from the virus, preventing it from jumping between cells.
A study found that no-nose bicycle saddles reduce saddle contact pressure, improve penile tactile sensation, and enhance erectile function in bicycling police officers. The use of no-nose saddles also led to a significant decrease in genital numbness while cycling.
University of Florida researchers have discovered a marine compound called largazole that inhibits cancer cell growth in laboratory tests. The compound is derived from cyanobacteria and targets histone deacetylase enzymes, which are associated with several cancers.
Researchers have shown that our visual working memory can be shared out across the whole image, with more memory allocated for objects of interest and less for background detail. This means that we don't just remember every detail, but focus on the broad gist and specific details.
Researchers at Penn State have discovered a new way to cool using ferroelectric polymers that exhibit temperature changes under an electrical field. The technology could lead to the development of flat panel refrigerators without coils or compressors, providing a more energy-efficient and environmentally friendly cooling solution.
Climate models predict a nearly ice-free Arctic Ocean by 2050, which will restore conditions that allowed Pacific shellfish to invade the Atlantic three million years ago. Several north Pacific species have relatives in the North Atlantic and are expected to resume their invasion when cold conditions return.
Researchers at Arizona State University have made a breakthrough in understanding the effect of brown carbon on climate change by developing a novel technique to measure its optical properties. This discovery could lead to more accurate forecasting of global warming activity, as current models often overlook this key component.
Researchers discovered how microRNAs fit into the map of embryonic stem cell circuitry, providing clues for targeting specific microRNAs to direct an embryonic stem cell into another type of cell. The study also provides a better platform for analyzing microRNA gene expression in cancer and other diseases.
Patrick Crowley, a computer architect, is designing a new network for the US Department of Defense to facilitate real-time information sharing. The goal is to enable commanders to understand the location and status of all platforms, equipment, and personnel in real-time.
A new study has identified younger, recently diagnosed men and those who binge drink and use substances like methamphetamine as high-risk groups for HIV transmission. These findings suggest the need for more targeted prevention programs to address the rising rates of HIV diagnoses among these men.
A UC Irvine study found that only 17% of adults with cardiovascular diseases have optimal levels for all lipids, compared to 85% of those without heart disease. The researchers emphasize the importance of proper diet, exercise, and medication to target all lipids.
A new study explores how imagination, insight, and creative ideas develop and spread within teams. Team creative cognition refers to a shared repertoire of cognitive processes among team members that enables the team's ability to approach problems creatively.
Robert Siliciano, an HIV expert, says that current antiretroviral drug combinations can suppress the ability of HIV to replicate, with some combos reducing copies to less than one in a billion. However, progress is still needed to identify and eliminate viral reservoirs that persist in the body.
A research team at Georgia Tech is developing foundational research in massive data analysis and visual analytics. The project aims to improve the visual analytics of massive data sets through machine learning, numerical algorithms, and optimization.
Researchers investigated estrogen's action in the brain, finding that it protects neurons and enables learning and memory throughout life. Estrogen receptors are present in both men and women, and a protein called PELP-1 enables rapid hormone action.
Dr. Eric Lazartigues' research aims to understand the role of ACE2 in regulating blood pressure and developing new treatments for hypertension. With a $1.2M grant, his work has the potential to improve the treatment of cardiovascular diseases, which claim more lives than cancer combined.
A new University of Washington study reveals that abstinence-only programs do not effectively prevent teenage sexual activity because they fail to speak the same language as adolescents. The research found that attitudes and intentions about sex were more powerful than those about abstinence, leading to increased instances of teen sex.
Researchers at University of Illinois and Northwestern University develop high-performance hemispherical camera using stretchable optoelectronics. The camera's design is based on the human eye, with a simple lens and hemispherical detector, enabling broader field of view and improved illumination uniformity.
A new study suggests that monitoring fibroblast growth factor 23 (FGF-23) levels can provide crucial information for the treatment of kidney failure patients. Elevated FGF-23 levels have been linked to a significantly increased risk of death among dialysis patients, even when phosphate levels are normal.