A new quantitative analysis method uses computerized measurements to evaluate liver biopsy samples, providing accurate assessments of fibrosis and inflammation. The Metriser technology offers a faster and more objective alternative to traditional scoring systems.
Researchers have identified trapped water as the cause of regular tremors under Vancouver Island, explaining episodic tremors every 14 months. The study provides a detailed glimpse into the geological mechanics beneath the island, bringing scientists closer to understanding earthquake cycles.
Research on Scutellaria barbata extract reveals growth inhibitory effects on human cancers, including lung, breast, and digestive system cancer. The extract induces apoptosis in hepatoma cells through the mitochondrial pathway, suggesting a potential therapeutic approach.
Astrophysicists used new computer visualization technology to understand that gravity plays a more significant role than previously thought in deep space's star-forming molecular clouds. The research, led by Alyssa Goodman, reveals hierarchical structure and density variations within these clouds.
A research team at UC San Diego has identified a protein called versican that enhances metastasis by stimulating inflammatory cells. Versican is found in low amounts in normal lung epithelial cells but is upregulated in aggressive lung tumors, supporting the growth and spread of cancer.
Research team investigates Campylobacter jejuni pathogenesis, finding two distinct patterns of interaction with epithelial cells. Strains that invade epithelial cells destroy them, while those that don't affect barrier properties or increase mediator production.
Researchers have made significant progress in defining the genetic signature of Alzheimer's disease, a complex neurodegenerative disorder. The study identified a new SNP on chromosome 12q13 and confirmed the known apolipoprotein E association, revealing that 50% of the genetic risk effect remains unexplained.
A new study from Tel Aviv University found that occupational stress has no effect on epilepsy attacks, with a large sample size allowing for high predictive power. The research benefits those who have been seizure-free for a long period of time, showing they are likely to stay seizure-free.
A team of Johns Hopkins neuroscientists has discovered a new type of light sensor in the eye that detects light and communicates with the brain. These melanopsin-containing cells are insensitive to light, but their signal is large enough to influence the brain when activated by multiple photons.
A new Brandeis University study reports that academic medicine faces a toxic culture leading to faculty burnout and disconnection, affecting patient care and professional relationships. The study identifies serious problems with relational culture, competitive individualism, and deprecation among medical faculty members.
A study by researchers from the University of Kentucky found that grape-seed extract induces apoptosis in leukemia cells by activating the JNK pathway, leading to cell cycle regulation and death. The extract has shown promise as a potential agent for preventing or treating hematological malignancies.
Researchers found that administering antibiotics as a preventive measure to patients in intensive care units increases their chances of survival, with a reduction of 3.5% in ICU deaths. The study involved nearly 6,000 patients and showed that using antibiotics resulted in fewer deaths compared to standard ICU care.
Researchers found that silencing of a crucial gene in lung cancer leads to impairment in genome-wide changes, contributing to cancer development and progression. Tobacco use is strongly linked to modification of the MTHFR gene, which triggers global hypomethylation and deregulation of DNA synthesis.
A new study reveals that smokers with a family history of brain aneurysm are significantly more likely to suffer a stroke. The research found that current smokers were six times more likely to experience a stroke, and quitting smoking could reduce this risk by over half.
Researchers have discovered a key difference in hormone receptors on prostate cancer cells in patients who no longer respond to hormone deprivation therapy. The finding, published in Cancer Research, could lead to new targets for treating prostate cancer and monitoring disease progression.
Researchers at Albert Einstein College of Medicine developed a technique to make foreign pancreatic cells invisible to the immune system, dramatically protecting them from rejection. The new method could pave the way for routine use of cell transplants as a therapy for type 1 diabetes in humans.
The Hubble Space Telescope is set to undergo its fifth and final service mission, which will provide the telescope with a future as bright as its past despite being nearly 18 years into troubled beginnings. The repairs will upgrade instruments, replace gyroscopes and heat shields, and add new capabilities for deeper observations.
Research found a high prevalence of gluten-sensitive enteropathy (GSE) in patients with iron deficiency anemia of unknown origin. A gluten-free diet improved anemia in GSE patients with mild duodenal lesions, suggesting GSE as a potential cause of iron-deficient anemia.
A systematic review and meta-analysis found that bismuth compounds were associated with a low risk of adverse events, with the exception of dark stools, which has little clinical significance. The study suggests that bismuth-containing regimens may be a safe alternative to PPI-based triple therapies for H. pylori eradication.
University of Missouri researchers are creating a comprehensive database of soybean proteins and metabolites to study changes under drought and stressed conditions. The database will help breeders engineer better-performing soybean plants using computerized models that predict physiological and biological changes.
Researchers found that laminin-111 restored regenerative capacity in a mouse model for alpha 7 integrin congenital myopathy. The protein promotes muscle cell health and survival by interacting with the extracellular matrix.
A study by University of Miami professor Michael McCullough found that religious people have more self-control than their less religious counterparts. This increased self-control can lead to better school achievement, lower rates of substance abuse, and longer lives.
Researchers found that irradiation damages fat tissue in mice, reducing its weight and size, and altering its ability to support reconstruction. Additionally, a study on multiple sclerosis found that CXCL1 decreases disease severity by promoting remyelination. A new molecule, FPR-2, has been identified as a potential anti-inflammatory ...
A comprehensive review of 241 gene variants and cancer risk identified only two statistically significant associations, including an XRCC1 allele and ERCC2 allele linked to lung cancer. The findings suggest that genetic risks are typically modest, and large-scale evidence is needed to establish specific associations.
A study by Columbia University Medical Center researchers found that rising blood glucose levels may contribute to normal cognitive decline in aging. Exercise has been suggested as a potential strategy to improve cognitive health by lowering glucose levels and improving brain function.
A new clinical trial suggests that long-term use of candesartan may significantly reduce symptoms of genetic heart disease, including left ventricular hypertrophy. The study found no adverse effects of candesartan use and highlights the need for customized treatment protocols based on individual patient gene mutations.
A study by Ohio State University researchers found that the molecule miR-29 is essential for muscle repair and maturation, but its absence is linked to rhabdomyosarcoma cancer. Raising miR-29 levels in cancer cells slowed tumor growth and induced maturity.
Researchers at Johns Hopkins University School of Medicine have discovered a potential new approach to cancer therapy by manipulating the tail of a tumor suppressor protein. By removing its tail, the protein becomes active and can effectively suppress cancer growth.
A randomized controlled trial found that women taking vitamin C, E, or beta carotene had a similar risk of cancer as those not taking the supplements. Antioxidant supplements were previously thought to lower cancer risk due to high fruit and vegetable intake, but this study contradicts those findings.
A recent study published in the Journal of Clinical Oncology found that medication errors involving chemotherapy are common in outpatient cancer treatment settings. The study revealed that adults and children alike were at risk of receiving incorrect doses or experiencing other medication-related mistakes.
Researchers found that individuals with a higher novelty-seeking personality trait have decreased dopamine autoreceptor availability, making them more responsive to novel and rewarding experiences. This may contribute to the development of drug abuse and other unsafe behaviors.
Michigan State University scientists have successfully validated a pathogen-killing technology using X-rays, which can effectively eliminate E. coli and salmonella from leafy greens without altering product quality.
Researchers discovered a weakness in the MD5 algorithm that allows for the creation of rogue certification authorities, which can be trusted by all major web browsers. This opens the door for virtually undetectable phishing attacks, compromising user passwords and private data.
A new INFORMS study suggests automakers must balance short-term price savings with long-term product life cycle implications when considering outsourcing production. The study finds that in-house development allows for higher performance improvement over the entire product life cycle.
Researchers at Tel Aviv University discovered that transfusions of 'young' blood –– blood stored for less than 9 days –– increased the odds of survival in animals with leukemia and breast cancer. Fresh blood may be a game-changer in cancer treatment, potentially improving survival rates.
Research suggests cisplatin ototoxicity is due to higher platinum concentration in inner ear, while high insulin levels are an independent risk factor for breast cancer. Studies found significant correlations between fasting insulin and increased breast cancer risk.
A University of Missouri study found that strong self-efficacy can help women succeed in engineering, but feeling included is a significant barrier. The research suggests changes to education practices can improve the pipeline for women engineers.
Researchers at MIT have designed gold nanoparticles that can deliver multiple cancer drugs in a controlled fashion using infrared light. The system allows for precise timing of release, enabling treatment of diseases commonly treated with multiple drugs.
Adult cystic fibrosis patients can accurately predict their mortality based on their own reported quality of life. Patient-reported pain was found to be a critical factor in determining survival rates, highlighting the importance of using patient-reported measures in clinical trials.
Researchers at Thomas Jefferson University's Center for Translational Medicine successfully reversed heart damage in rats with heart failure using gene therapy. The treatment, which involves administering a peptide called βARKct, inhibited the activation of a kinase that contributes to heart failure deterioration.
Researchers found that grazing animals like deer and rabbits increase the prevalence of a viral plant disease by promoting the growth of aphid-preferred annual grasses. This study challenges previous theories suggesting that herbivores help contain or reduce disease, highlighting the complexity of natural ecosystems.
A new study published in Pediatrics reveals that only 10% of overweight children receive a proper diagnosis, while 76% of severely obese children and 54% of obese children are accurately identified. The study emphasizes the need for early intervention and innovative solutions to improve pediatric weight detection.
A recent study published in the World Journal of Gastroenterology investigated the gastrointestinal side effects of high-dose acetaminophen and NSAIDs. The research found that gastric lesions were similar between groups, indicating that acetaminophen is not entirely free of gastrointestinal side effects at high doses.
A recent study by UT Southwestern Medical Center found that managed-care plans did not improve the quality or outcome of care for patients undergoing carotid endarterectomy. The study examined data from over 11,400 cases and found no difference in rates of inappropriate surgery between managed-care and fee-for-service plans.
Researchers found that the DE3 tide can propagate above 100km and exhibits a 2-year cycle oscillation. The tidal signal was analyzed using TIMED mission data, revealing two dominant Hough modes with annual unimodal distribution.
A new study by San Francisco State University Psychology Professor David Matsumoto found that facial expressions of emotion are innate and not learned. The research shows that sighted and blind individuals use the same facial expressions in response to emotional stimuli.
Researchers discovered that pills used to treat fungal infections improve symptoms of asthma in those with an allergic reaction to fungi. Nearly 60% of patients taking the drug showed significant improvement.
A high-fat diet can affect circadian rhythms, leading to hormone imbalance, obesity, psychological disorders, and cancer. Fasting and a low-fat diet regulate adiponectin signaling pathways, while a high-fat diet disrupts these pathways, contributing to metabolic disorders.
A study by Seong-Hyun Park and Richard H. Mattson found that hospital patients with plants in their rooms had fewer intakes of pain medication and more positive physiological responses. Patients interacted with the plants, such as watering and pruning, indicating a therapeutic benefit.
A study by American Society for Horticultural Science evaluated direct-seeding short-day onions in southeastern Georgia. Direct seeding was found to be a cost-effective alternative to traditional hand-transplanting methods, which rely on a migrant labor force.
A study by The University of Manchester found that patients with severe asthma and allergic sensitivity to certain fungi experience significant improvements in quality of life and lung function after taking an antifungal drug. However, symptoms often return after treatment is stopped.
A survey of employers highlights the importance of technical knowledge, practical application, and problem-solving skills for landscaping and horticulture students. Web-based case studies utilizing technology provide students with practical experience in solving complex scenarios.
Researchers found that applying municipal leaves to soil surface increased clean pumpkin fruit percentage by up to 25% compared to bare soil. This study provides a win-win solution for farmers and taxpayers, reducing leaf disposal costs while improving soil health.
A study by University of Maryland researchers has identified a common gene variant associated with an increased risk of developing high blood pressure. The STK39 gene produces a protein that helps regulate salt processing in the kidneys, which plays a key role in determining blood pressure.
Chronic gastrointestinal symptoms such as GERD, uninvestigated dyspepsia, and IBS are common in the Korean population. These conditions significantly impair quality of life, particularly in females, the elderly, and those with lower economic classes.
A recent study found that adding human hair waste cubes to commercial growth medium can increase plant yields relative to untreated controls. However, results showed lower yields compared to inorganic fertilizers, suggesting hair waste should not be used as a single source for fast-growing crops like lettuce.
A recent study by Kansas State University researchers found that gardening provides moderate-intensity physical activity, influencing whole-body bone mineral density and improving mental health. Gardening tasks change throughout the season, making it a great way for older adults to meet recommended physical activity levels.
Researchers at UC Davis Cancer Center have discovered a molecule called LXY1 that targets glioblastoma, a deadly form of brain cancer. The molecule binds to alpha-3 integrin on cancer cells, allowing for direct delivery of treatments and sparing normal tissues.
A study found Transcendental Meditation (TM) significantly reduced ADHD symptoms, stress, and anxiety among middle school students. TM improved attention, working memory, organization, and behavior regulation, enabling teachers to teach more effectively.
A recent study suggests that Neanderthals went extinct due to competition with Cro-Magnon populations. The researchers used a predictive method to analyze the distribution of archaeological sites and reconstructed climatic conditions during this period.