Scientists at Virginia Tech have found a novel mechanism for demineralization of noncrystalline silicas, which can dissolve up to 100 times faster than expected. This breakthrough has significant implications for the development of biomedical implants and synthetic materials with bone-like properties.
Researchers from Harvard Medical School and Brandeis University used a full-genome RNAi screen to identify genes essential for brain development in neurons. The study revealed unexpected roles for genes involved in signaling, protein trafficking, and cytoskeletal proteins.
Researchers at St. Jude Children's Research Hospital found that the loss of NEU1 triggers a catastrophic fall in biochemical dominos leading to disrupted hematopoietic stem cell formation and enlarged spleens. The study sheds new light on the cause of sialidosis and its link to bone marrow transplantation failure.
A study by Johns Hopkins Children's Center found that 40% of pediatricians wouldn't reduce medication doses even if a child is well-controlled. The researchers suggest that pediatricians might benefit from a step-by-step tool to apply treatment guidelines and use different disease dimensions in their practice.
Scientists identified a new antitumor drug, argyrin A, derived from the myxobacterium Archangium gephyra, which stabilizes the tumor suppressor protein p27kip1. The peptide induces apoptosis in cancer cells and prevents new tumor blood vessels from forming.
The Alfred Wegener Institute has inherited the World Radiation Monitoring Center, providing climate research with accurate meteorological data. The archive contains baseline energy conversion of solar radiation and thermal radiation data from around the world.
A study published in Pediatrics found that a single dose of vitamin A given to newborns shortly after birth can reduce their risk of death by 15%. This low-cost intervention has the potential to save millions of lives, particularly in developing countries where childhood mortality is highest.
A study published in PLOS Medicine found that a public-health approach to HIV treatment in South Africa is equally effective as an individualized approach used in Switzerland. Treatment initiated early greatly reduces HIV levels and viral rebound, but higher mortality rates were observed in South Africa.
Researchers found that female mosquitoes are attracted to water containers with specific fatty acids and methyl esters from bacteria, which stimulate them to lay eggs. The study aims to use this knowledge to devise lures and traps to control yellow fever mosquito populations, preventing global diseases like dengue fever.
Two leading authors stress the importance of teaching children to enjoy reading, rather than just reading, to improve literacy. They also highlight the role of teachers and parents in nurturing young readers and provide practical guidance on how to promote reading for pleasure.
Researchers at Stanford University School of Medicine have identified a molecule that selectively kills kidney cancer cells without harming healthy ones. This breakthrough finding could lead to the development of a life-saving treatment that preserves patients' kidneys.
Researchers identified resveratrol as a substance with anti-breast cancer properties by blocking estrogen DNA adducts. The study suggests that resveratrol may play a crucial role in preventing breast cancer.
Scientists at Thomas Jefferson University have discovered a key mechanism of breast cancer metastasis, where a gene dubbed 'Dachshund' (DACH1) regulates the production of IL-8, a common inflammatory protein. Blocking this protein with an antibody completely halted breast cancer spread in mice.
A new ovarian stimulation technique allows women with cancer to collect eggs for freezing during the luteal phase, reducing wait time before treatment. The technique has shown promising results in triggering ovulation and collecting mature eggs within two weeks.
Researchers at UT Southwestern Medical Center have identified a new target for RNAs that regulate genes, finding that these tiny strands bind to non-coding RNA transcripts and recruit proteins to activate or inhibit gene expression.
Researchers used a model to study stress changes on faults after the May 12 China earthquake and found heightened rupture likelihood for some faults. The study suggests that potential for failure exists on some faults, but does not predict when or if an earthquake will occur.
A study by the University of Exeter reveals a disturbing rise in cetacean strandings off Cornwall's coast, with most incidents attributed to bycatch in marine fisheries. The researchers are calling for increased conservation efforts and regulations to safeguard the future of Cornish cetaceans.
Researchers at ESMO Conference Lugano report improved treatment outcomes for aggressive non-Hodgkin's lymphoma patients when chemotherapy is administered every 2 weeks, rather than every 3 weeks.
A recent study by Dr. Stéphanie Belloc found that men over 35 have a negative impact on pregnancy rates and increase miscarriage risks in women undergoing intrauterine inseminations (IUIs). This marks the first time a strong paternal effect has been shown, contradicting previous assumptions about the role of the father in fertility.
A new approach to biofuel production uses plants to make enzymes, reducing costs and increasing efficiency. The technology, developed by Texas A&M University researchers, can produce multiple products from a single crop, making it a more economically viable option.
Scientists have identified marine species that produce compounds interfering with NF-kB, a protein linked to cancer and other diseases. These compounds may allow normal cell death in cancerous cells, while also improving drug delivery to tumors and other targeted areas.
Researchers found that circulating tumor cell counts accurately predict treatment response and survival in castration-resistant prostate cancer. Patients with declining cell counts showed improved prognosis, reflecting potential therapy benefits.
Men with breast cancer often experience poor outcomes due to delayed diagnoses, with 50% of cases reaching advanced stages. Early detection and treatment are crucial, as hormone therapy can be highly effective in treating the disease.
Research among 187 women from the general population found that younger women are more willing to become surrogate mothers. Women who value families and parenthood are also more likely to be willing to help others become parents. The study aims to overcome stigma by linking surrogacy to positive family values.
Researchers have discovered that Tabebuia extract can delay dietary fat absorption in animal models, reducing triglyceride levels. The extract's potential use in treating obesity and associated diseases like type 2 diabetes and coronary heart disease is being explored.
A new study suggests that more aggressive treatment of childhood eczema could help reduce the incidence of asthma in later life. The study, conducted by the University of Melbourne and others, found a strong association between childhood eczema and asthma into middle age.
A recent study published in The Lancet found that extracorporeal life support (ELS) combined with conventional CPR significantly improves survival rates in adult hospital patients who experience cardiac arrest. ELS enhances coronary blood flow and keeps heart tissue alive, leading to better 30-day and 1-year survival outcomes.
A new study led by Dr Alexandra Sänger found that slower exercise methods, such as SuperSlow, increase muscle mass and reduce connective tissue, benefiting menopausal women. The results suggest that these exercises may contribute to a better quality of life in old age.
Researchers at Wageningen University used special horseshoes to measure accelerations of horses undergoing aquatraining and walking normally, revealing lower impact forces during 'aquatic walking'. However, rising trot may not be as advantageous as previously thought, with similar back extension in both sitting and rising trot.
A recent clinical trial found that xylitol syrup administered daily to toddlers from 6-15 months old significantly reduced tooth decay. The study showed nearly 76% of children in the xylitol group were caries-free, compared to 48% in the control group.
A study of 39 surrogacy families, 43 donor insemination families, and 46 egg donation families found that relationships within these families appear to be well-functioning, with similarities in psychological wellbeing and parent-child relationships compared to naturally conceived families. However, teachers reported slightly higher lev...
Researchers find that wing shape and flapping motion are crucial for efficient flight, contradicting the assumption that nature is always efficient. Dr. Jim Usherwood's study suggests that mimicking nature's designs can lead to flawed results, highlighting the importance of understanding aerodynamics in biomimetics.
Researchers have developed a novel hydrogel system using multidomain peptides as a biomimetic scaffold, enabling the directed differentiation and function of dental stem cells for targeted dentin-pulp complex regeneration. The material provides high control over nanofiber architecture and better chemical functionality.
Research reveals that resolvins and protectins, derived from omega-6 and omega-3 fatty acids, counter-regulate pro-inflammatory signals and promote tissue healing in diabetes. These mediators reverse inflammatory responses in polymorphonuclear leukocytes and macrophages, offering potential for new therapeutic options.
A study of 206 pregnant women found that mothers with low vitamin D levels had children more likely to develop early childhood tooth decay, while those with adequate levels had children with fewer enamel defects. Vitamin D consumption and prenatal use also influenced the risk.
Primary care physician dental referrals increased access to dentists for children with tooth decay, but utilization remained low. Factors such as child age, general dentist availability, and rural location influenced referral effectiveness.
Researchers discovered that nanostructures enhance bone formation on titanium implants as early as 4 weeks after placement. Modifying the size and distribution of nanostructures at the implant surface may lead to faster and more predictable results.
New estimates from Great Ape Trust reveal declining orangutan populations, with 75% living outside national parks. Conservation efforts must focus on island-specific action to address ecological threats.
Researchers used a rare double-star system to test Albert Einstein's theory of General Relativity, finding that the famed physicist's 93-year-old theory has passed yet another test. The study confirmed that the strong gravity of the neutron stars causes one to wobble or precess.
Researchers found that toads in suburban areas are less likely to suffer from reproductive system abnormalities than those near farms. The study highlights the difference between the impact of agriculture versus development on amphibians.
University of Manchester researchers have received £1.6 million in funding to study a group of genes identified as playing a key role in leukaemia. The grant will help analyze the common mechanisms of action for patient benefit, potentially leading to the development of targeted therapies.
Ben-Gurion University of the Negev has reached a strategic cooperation agreement with Microsoft's R&D Center, enabling joint research projects and internships for outstanding students. The partnership aims to create a talented group of programmers and develop next-generation technology innovations.
MESSENGER data reveals widespread volcanism on Mercury's surface, with lava plains and iron-deficient rock units mapped. The spacecraft has identified three major rock units and confirmed an apparent planet-wide iron deficiency in Mercury's surface rocks.
The oceans have absorbed 40% of human-caused carbon dioxide, causing a 0.1-unit drop in surface pH; acidification may harm corals and plankton by mid-century if emissions aren't reduced. Carbon dioxide levels could reach 0.35 units by the mid-21st century if cuts aren't made immediately.
Researchers from Brown University have discovered evidence of past volcanic activity on Mercury, suggesting that the planet underwent intense changes to its landscape around 3-4 billion years ago. The findings were made possible by detailed images from NASA's MESSENGER spacecraft and provide new insights into Mercury's geologic history.
Researchers analyzed fecal samples from 25 chimpanzee communities and found a range of SFV infection rates from 44% to 100%. The study highlights the importance of understanding cross-species infections in primates and their potential impact on human health.
A new nurse-delivered complex care package has been shown to reduce levels of depression in cancer patients and improve their quality of life. The intervention, known as Depression Care for People with Cancer, was found to be cost-effective, with a median cost per quality-adjusted life-year gained of £10,000.
Researchers have identified a new target for TB treatment, solving a long-standing puzzle about bacterial cell wall production. The discovery reveals molecules that could be developed into drugs to treat tuberculosis, particularly for multi-drug resistant strains.
Resveratrol slows age-related deterioration and functional decline in mice, improving cardiovascular function, bone health, and motor coordination. However, it does not increase longevity when started at middle age.
Researchers found that diversity among ancient marine creatures like clams and lobsters showed only a modest rise beginning 144 million years ago. The study contradicts previous work suggesting dramatic increases in diversity, providing insight into future diversity and the impact of global warming.
A new study from Baycrest Centre for Geriatric Care overturns the notion that brain noise decreases with maturity. Brain maturation leads to more stable and accurate behavior in memory tasks, but also correlates with increased brain signal variability.
Researchers confirmed Einstein's theory of general relativity using observations of a unique pulsar system. The discovery shows that one pulsar is 'wobbling' in space, a effect precisely as predicted by Einstein.
A new vitespen vaccine was tested on post-operative kidney cancer patients, but showed no significant improvement in recurrence-free survival. In early stage disease, patients receiving the vaccine had a lower risk of recurrence, but this finding requires further validation.
New research from Vanderbilt University has found that mental imagery--what we see with the "mind's eye"--directly impacts our visual perception. The study, published in Current Biology, discovered that a short-term memory trace formed by imagery can bias future perception.
A new study finds that nature reserves in Africa and Latin America attract human settlement, with population growth near protected areas being nearly twice that of neighboring rural areas. The researchers attribute this to economic incentives provided through international aid and donor investment, which stimulate local economies.
A long-term study shows that resveratrol improves bone health, reduces cataracts and cardiovascular dysfunction, and enhances balance and motor coordination in middle-aged mice. The study also found that resveratrol induces gene expression patterns similar to those induced by dietary restriction.
Researchers at UCLA have solved the structure of sodium glucose co-transporters (SGLTs), which pump glucose into cells. This breakthrough may lead to improved treatments for diabetes and obesity.
Research found that communities with a large number of Catholic and Mainline Protestant churches tend to have lower mortality rates due to their emphasis on community outreach and public charity. In contrast, Conservative Protestant churches often focus on individual relationships with God and may lead to higher mortality rates.
A University of Michigan instrument on the MESSENGER spacecraft has detected silicon, sodium, sulfur, and water ions around Mercury, suggesting that they were blasted from the surface or exosphere by solar wind. The findings provide a new understanding of Mercury's composition and its interaction with the sun's magnetic field.
Researchers at McGill University confirmed Einstein's prediction that a binary-pulsar system's spin axis should precess due to general relativity. The team observed the unique PSR J0737-3039A/B twin-pulsar system and found that one pulsar's spin axis is indeed precessing as predicted.