The debut issue of Foot & Ankle Specialist features a 3-step treatment plan for patients with diabetic foot infections, recommending tissue removal followed by comprehensive assessment and restructuring. This approach can help prevent limb loss, enabling practitioners to provide the best current diagnosis and therapy.
Research found that DDT's main metabolite, p,p'-DDE, disrupts hormone-sensitive breast cancer cells by opposing the androgen signalling pathway. This suggests a new mechanism for breast cancer progression, potentially favouring tumour growth in women.
A study published in BMC Medicine found that UK medical graduates from different schools perform significantly differently on national exams. The researchers argue that a national licensing exam is needed to standardize the training of doctors. The results showed that some medical schools teach skills not assessed by current exams.
Climate scientist James Hansen receives AAAS Award for Scientific Freedom and Responsibility for his outspoken advocacy on human influence on global climate. The award recognizes his efforts to protect the public's health and safety by communicating openly with the public about critical research findings.
A new study by the National Institutes of Health found that a stent designed to open clogged brain arteries was successfully deployed in nearly all cases and reduced arterial blockage, but long-term benefits compared to medical treatment alone were inconclusive. A large-scale randomized trial is expected to provide definitive results.
A University of Alberta study analyzing over 275,000 individuals found that different factors influence participation in physical activity. Walking was the most common form of exercise, with older adults more likely to participate.
Burton Richter, a Nobel laureate in physics, has been awarded the 2007 AAAS Philip Hauge Abelson Prize for his outstanding contributions to research and public policy. The prize recognizes his work on energy and sustainable development, as well as his tireless advocacy for sound science in American government.
Researchers have identified a remarkably well-preserved fossil of the most primitive bat species known to date, Onychonycteris finneyi. The discovery reveals that bats evolved the ability to fly before developing echolocation, providing conclusive evidence for this evolutionary order.
Researchers at McGill University have discovered a genetic process that boosts an organism's natural anti-virus defences by knocking out genes repressing interferon production in mice. This breakthrough could lead to the development of new anti-viral therapies in humans, providing a potential solution to combat viral pandemics.
Carlos Castillo Chavez has been honored by the American Association for the Advancement of Science (AAAS) for his efforts to help underrepresented students earn doctoral degrees in the sciences. Through his summer research program, he has mentored numerous Hispanic Americans and Native Americans to graduate programs.
A new computer model, developed by University of Illinois ecologist Adam Davis, aims to predict the most effective biological control agent for reducing garlic mustard populations in temperate forests. The model uses simulation dynamics and testing protocols to identify a tiny weevil as a promising candidate.
A recent study reveals that dissolved organic carbon in Alaskan arctic rivers is remarkably labile during the spring flood period, challenging the prevailing paradigm. This finding suggests that riverine inputs of DOC may have a larger influence on coastal ocean biogeochemistry than previously realized.
A new study by Markus Giesler explores the seven-year conflict between music downloaders and corporate executives, revealing a four-act drama of market evolution. The research identifies a fundamental cultural tension between utilitarian and possessive ideals, influencing consumer behavior and producer statements.
Researchers found that when new products are released, consumers focus on the company's brand and perceptions. In contrast, when products have already been launched, evaluations are based solely on the brand's strength. This study reveals the importance of considering temporal frames in consumer research.
Scientists unveil Velafrons coahuilensis, a massive duck-billed dinosaur from Mexico's Cerro del Pueblo Formation. The discovery provides valuable insights into the region's ecosystem and mass death events, challenging previous understanding of West America's Late Cretaceous history.
A study found that prior knowledge can make it difficult for consumers to learn and recognize other positive qualities indicated by the same cues. The researchers used cheese tasting to explore this phenomenon, known as 'protection of prior learning.' The findings have important implications for marketers, policy makers, and consumers.
A new portable detection system developed by PNNL can accurately detect toxic lead and other heavy metals in blood, urine, and saliva samples. The device is field-deployable, battery-operated, and provides quicker results than current state-of-the-art mass spectrometry systems.
New research suggests the Americas were colonized by approximately 1,000-5,000 people, with a 20,000-year layover in Beringia, where population size remained relatively stable. This three-stage colonization model provides a more complex scenario than previous theories, shedding light on the timing and scale of the initial migration.
A study found that only 38% of US medical schools have adopted conflicts of interest policies covering financial interests held by the institution, while most have policies in place for individual officials. The gaps in coverage highlight the need for continued attention to address these challenges.
Scientists develop micro-scale tool to study how nerve cells in the brain work together, providing insights into growth and signaling molecules. The 'lab on a chip' system helps researchers understand complex interactions between neurons and their environment.
Researchers find that watching someone eat a snack will cause you to also eat more of it, while mimicked posture and speech lead to higher ratings and increased consumption. The study suggests that mimicry has the potential to be a valuable tool in interpersonal persuasion.
Researchers found that a tropical rainforest bird uses different song features to signal species identity and individual information, tailored to the environment's acoustic properties. The study suggests efficient local communication networks are established in the habitat.
Researchers at UW are testing a pilot project involving dozens of volunteers wearing electronic tags to track their location and belongings in the six-story building. The study aims to explore the benefits and drawbacks of RFID technology, including data privacy and personal space concerns.
Researchers at Schepens Eye Research Institute found that blocking VEGF can damage the cell lining preventing fluid from leaking into the brain. This may contribute to Avastin's neurological side effects in humans.
A 20-year review of studies found that active fathers reduce behavior problems in boys and psychological issues in young women. Regular positive contact also enhances cognitive skills like intelligence and language development.
Researchers identify the first protein to activate G-protein signaling from within a cell, opening up new pathways for drug development. The discovery of Arr4 could lead to more selective and effective medications with fewer side effects.
Patients with larger social networks report less pain and anxiety before surgery, which can positively impact their recovery. Clinicians should be aware of the link between social networks and patient recovery after major operations.
A team of psychologists found that people's emotional desire for a mate leads them to believe there are fewer desirable partners available, even when the numbers are equal. This 'value heuristic' affects judgmental decisions in everyday life and can sometimes lead to unrealistic assumptions about reality
A study found that breast cancer survivors, especially older women, are at a greater risk of dying from non-cancer causes than from breast cancer. Factors such as pre-existing diseases like heart disease and osteoporosis are associated with this increased risk. The researchers also found that women with cancer cells in the lymph nodes ...
A new study finds that eating a diet low in fat and red meat, but high in vegetables and lean protein, may significantly decrease the risk of symptomatic benign prostatic hyperplasia (BPH). This association is likely due to reduced inflammation and changes in steroid hormones.
A study published in the Journal of the National Cancer Institute found that HPV-positive head and neck cancer patients have higher response rates to chemoradiation therapy and better two-year overall survival rates compared to HPV-negative patients.
A new clinical trial at Thomas Jefferson University aims to test the effectiveness of radioembolization using radiation-emitting beads in treating advanced liver cancer. The treatment, which blocks blood supply and emits targeted radiation, has shown promise in shrinking tumors and improving patient survival.
A tonsillectomy and adenoidectomy has been shown to provide dramatic relief from obstructive sleep apnea (OSA) in children, with 80-90 percent experiencing significant improvement. The surgery can lead to a profound positive effect on children's quality of life.
A study led by Dana-Farber Cancer Institute researchers found that women with ductal carcinoma in situ (DCIS) often misperceive their risk of recurrence or dying from breast cancer, due to elevated anxiety. This can lead to poor treatment choices and negatively impact emotional well-being and health behaviors.
Researchers at Virginia Tech are developing a treatment for prostate cancer using the Newcastle Disease virus. The virus targets specific proteases secreted by cancer cells, generating apoptosis and killing diseased cells. This is a promising new approach to fighting cancer.
A recent study reveals that many US medical schools lack comprehensive policies addressing conflicts of interest related to financial interests of the institution itself or major officials. The study suggests that institutions may need additional support in addressing this issue, and raises questions about the effectiveness of existing...
Recent decades have seen a significant shift in oil palm research, with an increasing focus on the environment and biofuel production. However, biodiversity assessments remain scarce, particularly for insect species that carry out key ecosystem functions.
A team of scientists has successfully derived functional immune system blood cells from embryonic stem cells using HOXB4 protein. The study showed that the transplanted cells were able to respond effectively to viruses and vaccines, demonstrating a promising new approach for patients with severe blood and immune disorders.
A new study contradicts a prevailing belief about otoacoustic emissions, revealing they travel through fluid in the inner ear rather than rippling along the basilar membrane. The findings offer insight into hearing loss and could lead to the development of tools to detect damage.
A study found that women with ductal carcinoma in situ (DCIS) have overly optimistic views of their risk of recurrence and invasive breast cancer. Anxiety levels decreased over time, but depression remained low. Clinicians should be aware of these inaccurate perceptions to minimize distress.
Research at Columbia University's Mailman School of Public Health found that desire to weigh less was more predictive of unhealthy days than BMI, particularly among Whites and women. The study suggests social constructs surrounding ideal body types contribute to the obesity epidemic.
Using breast shields during pediatric chest MDCT reduces radiation dose and minimally increases image noise. The study found that shielding alone reduced the dose by 26%, while combining shielding with automatic tube current modulation (ATCM) reduced it by 52%.
A study by University of Illinois Chicago researchers found that Sept. 11 terrorism-related thoughts and fears are associated with increased psychological distress and alcohol abuse in Americans. The study measured the effect of macro-level sociological stressors on mental health, four years after the attacks.
Researchers at the University of Leeds have made a breakthrough in diagnosing pre-eclampsia, a condition that affects up to 15% of pregnancies. A user-friendly diagnostic kit is being developed to test pregnant women, with potential savings estimated at £500m for the NHS.
Researchers monitored 140 sleeping volunteers near London Heathrow and three major European airports, finding that aircraft noise increased systolic blood pressure by an average of 6.2 mmHg and diastolic blood pressure by 7.4 mmHg. The study's findings highlight the need to reduce night-time aircraft noise levels to protect public health.
Researchers discovered that scattering by impurities occurs in both the pseudogap and superconductive states, challenging existing theories. This finding could help understand why certain materials can superconduct at high temperatures.
A new study by University of Chicago Medical Center researchers found a remarkable overlap between the effects of nicotine and opiates on dopamine signaling in the brain's reward centers. The findings suggest that these two addictive substances share common underlying brain chemistry mechanisms.
A new study found that a 'lung open ventilation' strategy combining low tidal volumes, recruitment maneuvers, and high PEEP levels reduced the rates of severe persistent low oxygen levels and needed rescue therapies. The study also showed improved lung function and reduced organ failure duration.
A study by Thomas Kramer and Lauren Block found that consumers are more disappointed when a supposedly
Researchers at Yale School of Medicine have developed a blood test that detects early stage ovarian cancer with 99% accuracy, building on previous work showing 95% effectiveness. The new platform uses six protein biomarkers instead of four, increasing specificity from 95 to 99.4%.
Researchers at the University of Sheffield have created a revolutionary new technology that could transform medical scanning. The innovation enables instant analysis of medical screening tests and early detection of cancer, with potential to produce images as wide as the human torso.
A survey by Stevens Institute of Technology found that global companies operating in accelerating economies face a talent wall due to insufficiently trained technical personnel. The study revealed frequent conflict between local and headquarters management, with employees departing for cultural needs and training issues.
A field study of registered voters aged 18-23 found that negative 'attack' ads provoke more voter migration than positive ads. The researchers also discovered that young voters are more likely to weaken their support for a candidate after viewing an ad attacking their preferred candidate.
A study analyzing US adult data from 1997-2005 found that expenditures for back and neck problems increased substantially, with a 65% inflation-adjusted rise. Despite this, health outcomes such as functional disability and work limitations did not improve.
Western lowland gorillas have been observed mating in a unique face-to-face position for the first time in the wild. This behavior is rare among primates, with only bonobos frequently employing ventro-ventral copulation.
Researchers at Washington University developed a gene chip technology that can distinguish pneumonia from underlying critical illness in patients on ventilators. The method identified changes in 85 genes associated with immune system activation, allowing for early diagnosis and potentially improved recovery.
After Italy's comprehensive smoking ban in 2005, acute coronary events among adults decreased significantly, particularly in younger age groups, with a 11.2% reduction for those aged 35-64 and a 7.9% decrease for those aged 65-74.
A new study found that vehicle interlocks significantly reduce DWIs among first-time offenders, with a 60% lower risk of repeat offenses. This economic benefit is substantial, saving $3 for every dollar spent on interlocks.
Researchers found that leaky muscle cells cause fatigue in both marathoners and heart failure patients. An experimental drug that plugs the leak may provide relief from exhaustion for those with chronic heart failure.
Researchers at UCSD developed a gene therapy protocol that successfully activated the immune system in six patients with chronic lymphocytic leukemia. The protocol introduced a gene with potential to activate an immune response and resulted in the production of antibodies reacting against leukemia cells.