Researchers have developed ultra-sensitive probes to investigate vancomycin's working mechanisms, paving the way for more effective new drugs. By detecting surface stress on bacteria, scientists can identify the disruption of cell walls and potentially develop more powerful antibiotics.
Researchers found that pectin, a compound in fruits and vegetables, inhibits galectin 3, a protein linked to all stages of cancer progression. This discovery may lead to functional foods with added bioactive pectin and provide evidence for the importance of eating at least 5-a-day.
Researchers at University of Southern California reveal the atomic structure of APOBEC-3G, an enzyme that stops HIV replication. The discovery suggests new directions for developing anti-HIV drugs by targeting a viral protein that blocks the enzyme.
A study published in Nature Genetics has identified a novel hair-loss gene variant associated with male baldness. The research found that this gene, located on chromosome 20, is inherited from both parents and may account for the similarity in cranial hair growth between father and son.
Researchers developed models to estimate meal requirements and school closures to minimize the number of people infected. The simulations showed that school closures reduced the number of people infected with the virus, while voluntary quarantine and food distribution interventions had varying effects on disease spread and resource all...
Research studies and clinical registry data suggest that triple antiplatelet therapy achieves greater platelet inhibition than conventional dual antiplatelet therapy in patients undergoing percutaneous coronary intervention (PCI) with drug-eluting stents. This leads to reduced early mortality and major adverse cardiac events without in...
Two genetic variants on chromosome 20 increase male pattern baldness risk by sevenfold, affecting up to 14% of men. The discovery is a scientific breakthrough but does not guarantee a treatment or cure for the condition.
Researchers have found that optical coherence tomography (OCT) is the best tool available to detect vulnerable plaque, a possible cause of sudden cardiac death. OCT provides superior contrast and resolution in imaging the components of plaque, allowing for better understanding of coronary artery disease progression.
Research found that coronary heart disease symptoms presented in the context of stress were identified as psychogenic in origin when presented by women and organic in origin when presented by men. This study sheds light on why there is often a delay in diagnosing CHD in women, highlighting a gender bias in diagnosis and treatment.
A recent study suggests that olmesartan, a commonly used high blood pressure medication, can help reduce plaque in the coronary arteries of patients with stable angina. The trial involved 247 patients who received either 20-40mg/day of olmesartan or control, and showed significant decreases in plaque volume after 14 months of treatment.
Three new devices are being showcased to reduce blockages in peripheral and coronary arteries, providing cardiac support. The AngioSculpt device optimizes stenting of complex lesions with a low rate of complications.