The University of Bath will use the funding to launch spin-off companies and influence government policy through its research, aiming to enhance business-academia partnerships. The £44 million Knowledge Transfer programme aims to reduce barriers between businesses and academia.
A team of researchers from Massachusetts General Hospital has found evidence of cell-to-cell communication by amino acids, leading to faster recovery of hepatocyte activity. The study reveals that proline, a building block of collagen, plays a key role in this process.
A study found that periodontal disease caused by Porphyromonas gingivalis can reactivate latent HIV-1 in infected individuals. The bacteria induce histone acetylation, leading to HIV-1 reactivation. Maintaining oral hygiene is crucial for preventing AIDS progression.
A study found that parents with low income, limited education, and single status experience higher levels of stress, which increases the likelihood of their children developing tooth decay. Conversely, receiving treatment for a child's dental decay can decrease parental stress levels.
Research by Yale University reveals that bird feathers create bright colors through nanostructures resembling a sponge with air bubbles. The structures self-assemble as the feather grows, replacing water bubbles with air, and have significant implications for the role of color in birds' plumage.
Physicians can reduce radiation exposure by using tube current modulation in 'triple rule-out' coronary CT angiography. This technique reduces effective radiation doses from 9.9-31.3 mSv to 5.4-16.6 mSv, comparable image quality and less than nuclear stress test radiation.
A Norwegian Institute of Public Health study analyzed children's diets combined with psychological and sociodemographic variables in mothers. The results show that mothers with high negative affectivity are more likely to give their children unhealthy food, but not the opposite for healthy food.
Researchers found that allergens can bind to and travel through the epithelium of allergic patients but not healthy subjects. This transport mechanism is crucial for the development of allergic reactions.
Researchers found that dopamine neuron bursting activity is crucial for learning rewarding outcomes. The study suggests that the NMDA receptor plays a key role in regulating burst firing in dopamine neurons.
The project aims to create a Medicago HapMap, mapping the genetic variations in the legume to reveal which genome regions control symbiosis and other legume-specific traits. Legumes are a crucial source of dietary protein and environmentally-friendly fertilizer, providing millions of tons of nitrogen to plants.
Researchers at Penn have identified a fluorescent anesthetic compound, 1-aminoanthracene (1-AMA), that allows for precise imaging of anesthetics in the body. This new tool enables high-throughput screening of novel anesthetic compounds, which could lead to safer and more effective drugs.
Researchers at the University of Pennsylvania have found a new way to combat malaria by trapping parasites inside host cells. They identified an enzyme called calpain-1, which parasites use to break out of infected cells, and developed a method to block it, leaving parasites trapped.
A new study from the Sahlgrenska Academy reveals that big men are more susceptible to atrial fibrillation, a disturbance in the heart's rhythm. The risk of atrial fibrillation increases linearly with both body size and weight gain, putting larger men at higher risk.
A recent study by NYU researchers found that sports drinks can cause tooth erosion and hypersensitivity due to high levels of citric acid. The condition affects one in 15 Americans and can lead to severe tooth damage if left untreated.
New research suggests Titan, Saturn's largest moon, has a subterranean ocean of hydrocarbons and unusual topography, including mountains with lower elevations than surrounding plains. The findings may help explain the presence of large lakes of hydrocarbons at both poles.
The analysis reveals highly polarised gamma rays, providing insight into the central engine's magnetic field structure. The team favours a synchrotron model, suggesting that the jet lifted the magnetic field into space.
Researchers at Duke University have identified a receptor on human glioblastoma cells that may be an appropriate target for therapies. Activation of the neurokinin 1 receptor leads to increased cell growth, but blocking this activity can reduce cell death and potentially stall cancer growth.
Physicists at the University of Leeds and IBM Research have made advances in racetrack memory, a new kind of computer memory that could replace hard disks. The technology is estimated to be 100 times cheaper per bit than flash memory and promises faster speeds.
Scientists have re-examined Hawaii's formation, finding the Pacific oceanic plate moved under a drifting hotspot, creating a 50 million-year-old bend in the seamount chain. Mantel circulation models aid understanding of forces on tectonic plates and stress estimation for major earthquakes.
Researchers from Regenstrief Institute have developed a technology that allows public health officials to send instant alerts to doctors and hospitals using an existing clinical messaging service. This approach minimizes delays in notification, which can be critical in disease outbreak response.
A novel compound called azelaic acid has been identified as a primer for the plant's immune system, leading to increased systemic plant immunity and disease resistance. The discovery was made by researchers at Oak Ridge National Laboratory and the University of Chicago.
Researchers create 'composite doublers' that take stress from joints and allow it to pass through without stressing the structure, extending its lifespan. The technology also serves as a warning system for inspectors and road workers when it begins to wear out.
A study at the University of Erlangen found that reducing tube voltage from 120 kV to 100 kV lowered cardiac CT radiation doses in adult patients weighing 185 pounds or less by 39% without compromising image quality. The lower dose resulted in effective radiation doses ranging from 4.9 to 11.9 mSv, compared to 8.8 to 16.9 mSv at 120 kV.
A computer-based model has been developed to aid radiologists in diagnosing breast cancer by analyzing mammogram images. The model was trained on 48,744 mammograms and found that it could detect 41 more cancers than routine practice, with potential benefits including reduced unnecessary biopsies.
The study reveals the precise orientation of the Fenna-Matthews-Olson (FMO) antenna protein on the membrane, allowing for efficient energy transfer. The 'taco shell' protein plays a crucial role in connecting the peripheral chlorosome antenna complex to the reaction center.
Researchers found that beta-amyloid protein generates nitric oxide, which attacks and damages mitochondria in neurons. This damage leads to synaptic injury and eventual nerve cell death, contributing to Alzheimer's disease progression.
A woman developed a large blood clot in her left leg after eating grapefruit for breakfast every morning on an aggressive weight-loss diet. Treatment with clot-busting medication and a stent resolved the issue, but underlying factors included oral contraceptive use and an inherited mutation.
Researchers at NYU and Harvard created a bipedal, autonomous DNA walker that can move on its own using two fuel strands. The device forms base pairs as it moves along a track of DNA, creating energy for movement.
A new study suggests that astronauts need to modify their workouts to avoid extensive muscle loss during long-duration missions in space. Muscle biopsies taken from astronauts revealed an average of 15% muscle mass loss and 20-30% loss of muscle performance, posing risks to crewmembers' health.
Researchers discovered that naturally fluorescent molecules like NADH can be used to detect cancer cells. The team developed a non-destructive method to measure NADH levels in live cells, which could help differentiate between normal and cancerous cells at early stages of tumor progression.
A phase II study found that moxifloxacin, in combination with other drugs, significantly improved sputum culture conversion rates, potentially shortening tuberculosis treatment time. The results demonstrate moxifloxacin's antimycobacterial activity and suggest a new regimen could cure drug-resistant TB strains.
A study published in Science has provided molecular evidence for the theory of synaptic homeostasis, which suggests that sleep refreshes the brain by downscaling synapses. This process saves energy, space, and material, clearing away unnecessary proteins and 'noise' from the previous day.
Whitehead Institute researchers have identified 24 prion candidates in yeast, shifting the view from biological anomalies to mediators of trait inheritance. Prions in yeast appear to prepare individual organisms for environmental changes, sometimes providing a survival advantage.
Researchers from Baylor College of Medicine discovered a molecular switch involving nuclear hormone receptors and microRNAs that coordinates stage transitions in Caenorhabditis elegans. This finding may provide insights into cancer development, particularly hormone-dependent cancers. The study suggests a link between development and en...
Researchers identified a genetic abnormality, CATSPER1, that may prevent men from conceiving. The gene's mutation affects sperm motility and hyperactivity, leading to potential targets for a pharmacological male contraceptive.
The American Society for Biochemistry and Molecular Biology has awarded several undergraduate students with grants to support their research in biochemistry and molecular biology. The recipients of the awards will present their findings at upcoming meetings and use the funds to purchase research supplies and reagents.
Dental amalgam has been deemed safe and effective for over 200 years, with the majority of health risks associated with large doses. A person would need hundreds of amalgam fillings to experience symptoms of mercury toxicity, according to Dr. Rod Mackert.
Researchers discovered a parasitic effect when powering quantum dot amplifiers and were able to overcome it, leading to the most efficient amplifier ever measured. This breakthrough has enormous potential significance for laser technology, telecommunications, and optical computing applications.
A new study published in the New England Journal of Medicine found that starting antiretroviral treatment earlier can significantly increase survival rates among asymptomatic HIV patients. The research, led by Dr. Mari Kitahata at the University of Washington, analyzed data from over 17,500 patients and showed that delaying treatment u...
A computer program using raw observational data teases out fundamental physical laws, particularly for biological systems that have eluded detection. The breakthrough uses a computational process inspired by biological evolution to analyze data sets and identify invariant patterns.
A University of Nevada, Reno alumna's innovative straw bale house design survived a 200% increase in acceleration than the 1994 Northridge quake. The structure, built using locally sourced materials and labor, demonstrated exceptional seismic performance, surpassing estimates for the 2005 Kashmir earthquake.
Researchers have found that human heart cells develop into adulthood around age 6, with the percentage of new cells decreasing significantly with age. This discovery may lead to new pharmacological strategies to stimulate heart cell regeneration and complement cell transplantation.
The UK Biobank project, which enlists 500,000 people to study disease development, faces criticism for its methodological flaws and lack of respect for participants' rights. The Editorial highlights issues with the consent process, including a lack of privacy and incomplete information disclosure.
A new catheter-based treatment has been successfully trialled to reduce high blood pressure in patients who resist conventional drug treatments. The technique, which disrupts nerves around the kidneys, showed a large and persistent decrease in blood pressure.
Researchers found that 58% of Isle Royale wolves exhibit congenital malformations, including lumbosacral transitional vertebrae. The condition can cause paralysis and back pain, with all dead wolves displaying bone deformities over the past 12 years.
Babies born to mothers who smoke are more likely to have impaired arousal responses and increased risk of Sudden Infant Death Syndrome (SIDS). The study suggests that maternal smoking can impair a baby's ability to respond to external stimuli, which may explain their increased risk of SIDS.
Researchers at Massachusetts General Hospital discovered a strategy to remove abnormal huntingtin protein from brain cells, accelerating its breakdown and removal through normal cellular processes. This finding could lead to new treatments for neurodegenerative disorders like Huntington's, Alzheimer's, and Parkinson's diseases.
Researchers have made significant breakthroughs in salivary diagnostics, discovering new biomarkers for detecting oral cancer, acute coronary syndrome, and systemic diseases. The study highlights the potential of saliva as a non-invasive diagnostic tool, offering clear clinical advantages over traditional methods.
Researchers found that jackdaws, a type of bird, are sensitive to human eye orientation and use it to communicate, particularly when seeking food or interacting with potential threats. The birds' ability to interpret human gestures, such as gaze alternation and pointing, suggests a high level of cognitive awareness.
Researchers found a strong association between reducing liquid calorie intake and weight loss, particularly from sugar-sweetened beverages. The study suggests limiting liquid calorie consumption among adults can aid in weight management or prevent excess weight gain.
Researchers at Johns Hopkins University found that brain cells in a specific region store visual information for up to two seconds, enabling the creation of a stable visual world despite rapid changes. This discovery may have practical implications for understanding and treating disorders such as attention deficit disorder and dyslexia.
Researchers teach computer to find regularities in nature that become established laws without prior knowledge, applicable to biology, cosmology, and complex systems. The algorithm tests equations against known derivatives, repeats until accurate equations are found.
A study led by the University of Bath found that children with Asperger Syndrome do not experience a surge in cortisol levels after waking, which may contribute to their struggles with minor changes. The researchers believe this could help explain why individuals with AS have difficulties adapting to routine or environmental changes.
A recent paper suggests legislation is only part of the solution to Europe's invasive species problem, with a single coordinating body needed to tackle the issue effectively. The European Centre for Invasive Species Management (ECISM) would coordinate activities across Member States and support rapid response and public awareness.
Researchers at MDC Berlin-Buch discovered a mechanism to prevent viral myocarditis by blocking the Coxsackie-adenovirus-receptor. Genetically engineered mice without this receptor were protected from cardiac infection caused by the Coxsackievirus, showing that autoimmune response may not be the primary cause of disease process.
Pulmonary rehabilitation improves aerobic function, reducing breathlessness in COPD patients. Supervised exercise also decreases anxiety and depression by enabling patients to master new skills.
Researchers found that sleep decreases the number of new synapses formed during social enrichment, while deprivation of sleep eliminates this decrease. The study identified three genes essential to links between learning and increased need for sleep, offering a promising avenue for studying plasticity.
Researchers studied autobiographical memory in semantic dementia patients according to disease progression, finding early-stage patients could recall recent and lasting memories. As dementia evolves, mechanisms behind autobiographical memory impairment result from storage deficits and faulty retrieval strategies.
Four young researchers under 45 received the 2009 ARVO-AFER/Merck Innovative Ophthalmology Research Award for their groundbreaking research on glaucoma and back-of-the-eye diseases. The award recognizes outstanding investigative work that could lead to meaningful improvements in patients' lives.
A new study found that boosting miR-29b levels in acute myeloid leukemia cells reverses gene changes, enabling the cells to differentiate and mature. This process could lead to a drop in global DNA methylation and reactivation of tumor suppressor genes, offering a potential treatment for AML.